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Journal of Neuroscience, Vol 12, 4309-4326, Copyright © 1992 by Society for Neuroscience
Temporal and harmonic combination-sensitive neurons in the zebra finch's HVc
D Margoliash and ES Fortune
Department of Organismal Biology and Anatomy, University of Chicago, Illinois 60637.
Song learning shapes the response properties of auditory neurons in the
song system to become highly selective for the individual bird's own
("autogenous") song. The auditory representation of autogenous song is
achieved in part by neurons that exhibit facilitated responses to
combinations of components of song. To understand the circuits that
underlie these complex properties, the combination sensitivity of single
units in the hyperstriatum ventrale, pars caudale (HVc) of
urethane-anesthetized zebra finches was studied. Some neurons exhibited
nonlinear temporal summation, spectral summation, or both. The majority of
these neurons exhibited low spontaneous rates and phasic responses. Most
combination-sensitive neurons required highly accurate copies of sounds
derived from the autogenous song and responded weakly to tone bursts,
combinations of simple stimuli, or conspecific songs. Temporal
combination-sensitive (TCS) neurons required either two or more segments of
a single syllable, or two or more syllables of the autogenous song, to
elicit a facilitated, excitatory response. TCS neurons integrated auditory
input over periods ranging from 80 to 350 msec, although this represents a
lower limit. Harmonic combination- sensitive (HCS) neurons required
combinations of two harmonics with particular frequency and temporal
characteristics that were similar to autogenous song syllables. Both TCS
and HCS neurons responded much more weakly when the dynamical spectral
features of the autogenous song or syllables were modified than when the
dynamical amplitude (waveform) features of the songs were modified. These
results suggest that understanding the temporal dynamics of auditory
responses in HVc may provide insight into neuronal circuits modified by
song learning.
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