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Journal of Neuroscience, Vol 12, 2104-2111, Copyright © 1992 by Society for Neuroscience
Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neurons
ML Roy and T Narahashi
Department of Pharmacology, Northwestern University Medical School, Chicago, Illinois 60611.
TTX-sensitive (TTX-S) and TTX-resistant (TTX-R) sodium channel currents
were analyzed in acutely dissociated dorsal root ganglion (DRG) neurons
isolated from 3-12-d-old and adult rats. Currents were recorded using the
whole-cell patch-clamp technique. TTX-R current was more likely to be
present in younger animals (3-7 d), whereas TTX-S current was more common
in older animals (7-10 d), although TTX-R current was recorded from adult
rat DRG neurons. The TTX-R and TTX-S currents differed in their
steady-state inactivation, with 50% inactivation voltage at -40 +/- 5 mV (n
= 10) for TTX-R currents and -70 +/- 4 mV (n = 10) for TTX- S currents.
These current types also differed in their activation kinetics, with 50%
activation values of -15 +/- 5 mV (n = 5) for TTX-R currents and -26 +/- 6
mV (n = 5) for TTX-S currents. The interactions of TTX-R and TTX-S channels
with various pharmacological agents and divalent cations were studied. The
Kd values for TTX-S and TTX-R currents were estimated to be 0.3 nM and 100
microM for TTX, 0.5 nM and 10 microM for saxitoxin, and 50 microM and 200
microM for lidocaine, respectively. TTX-S channels did not exhibit a marked
use-dependent block by lidocaine, whereas lidocaine significantly decreased
TTX-R current in a use-dependent manner at frequencies ranging from 1 to
33.3 Hz. Several external divalent cations exerted different effects on
these current types.(ABSTRACT TRUNCATED AT 250 WORDS)
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[Abstract]
[Full Text]
[PDF]
|
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[Abstract]
[Full Text]
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|
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|
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[Full Text]
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|
|
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|
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|
|
|
|
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276(49):
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[PDF]
|
|
|
|
|
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7909 - 7918.
[Abstract]
[Full Text]
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|
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86(3):
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6077 - 6085.
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[Full Text]
[PDF]
|
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86(2):
629 - 640.
[Abstract]
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[PDF]
|
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85(2):
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[Abstract]
[Full Text]
[PDF]
|
|
|
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|
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[Abstract]
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294(1):
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|
|
|
|
|
|
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83(4):
2431 - 2442.
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[Full Text]
[PDF]
|
|
|
|
|
|
|
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83(3):
1722 - 1732.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
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|
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277(6):
G1180 - G1188.
[Abstract]
[Full Text]
[PDF]
|
|
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|
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277(4):
C717 - C727.
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|
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|
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|
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August 1, 1999;
82(2):
700 - 708.
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[Full Text]
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|
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August 1, 1999;
19(15):
6497 - 6505.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
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96(14):
7635 - 7639.
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|
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|
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