WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (313)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bradley, D. J.
Right arrow Articles by Young, W. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bradley, D. J.
Right arrow Articles by Young, W. S., 3d

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 12, 2288-2302, Copyright © 1992 by Society for Neuroscience

ARTICLE

Spatial and temporal expression of alpha- and beta-thyroid hormone receptor mRNAs, including the beta 2-subtype, in the developing mammalian nervous system

DJ Bradley, HC Towle and WS Young 3d
Laboratory of Cell Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892.

Thyroid hormone exerts profound effects on the developing mammalian brain, and its deficiency can lead to severe mental retardation and motor abnormalities. To identify specific anatomic targets of thyroid hormone action in the developing mammalian nervous system, we examined thyroid hormone receptor gene expression by hybridization histochemistry on serial adjacent sections from 12 stages of the developing rat nervous system. 35S-labeled cRNA probes were generated from divergent sequences of rat alpha 1-, alpha 2-, beta 1-, and beta 2- thyroid hormone receptor and related cDNAs. We found that alpha- and beta-thyroid hormone receptor genes have distinct patterns of spatiotemporal expression in the embryonic and postnatal rat nervous system. alpha 1- and alpha 2-mRNAs were widely expressed in similar patterns; highest levels were found in the fetal neocortical plate, site of cortical neuronal differentiation. In contrast, beta 1- transcripts were restricted in distribution, with prominent expression in zones of neuroblast proliferation such as the germinal trigone and the cortical ventricular layer. Surprisingly, the "pituitary-specific" beta 2-transcript was detected in the developing hippocampus and striatum. Our results suggest that alpha- and beta-thyroid hormone receptors may play distinct functional roles during development of the mammalian nervous system.


This article has been cited by other articles:


Home page
 Hum Reprod UpdateHome page
S. R. Hansson, B. Bottalico, V. Noskova, and B. Casslen
Monoamine transporters in human endometrium and decidua
Hum. Reprod. Update, March 1, 2009; 15(2): 249 - 260.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
C. N. Walpita, A. D. Crawford, E. D. R. Janssens, S. Van der Geyten, and V. M. Darras
Type 2 Iodothyronine Deiodinase Is Essential for Thyroid Hormone-Dependent Embryonic Development and Pigmentation in Zebrafish
Endocrinology, January 1, 2009; 150(1): 530 - 539.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
R. A. Sinha, A. Pathak, V. Mohan, S. Bandyopadhyay, L. Rastogi, and M. M. Godbole
Maternal Thyroid Hormone: A Strong Repressor of Neuronal Nitric Oxide Synthase in Rat Embryonic Neocortex
Endocrinology, September 1, 2008; 149(9): 4396 - 4401.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
B. R. Noble, R. P. Babiuk, R. D. Clugston, T. M. Underhill, H. Sun, R. Kawaguchi, P. G. Walfish, R. Blomhoff, T. E. Gundersen, and J. J. Greer
Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen
Am J Physiol Lung Cell Mol Physiol, October 1, 2007; 293(4): L1079 - L1087.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
G. Czirjak, Z. E. Toth, and P. Enyedi
Characterization of the Heteromeric Potassium Channel Formed by Kv2.1 and the Retinal Subunit Kv8.2 in Xenopus Oocytes
J Neurophysiol, September 1, 2007; 98(3): 1213 - 1222.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
R. Keijzer, P.-J. E Blommaart, W. T Labruyere, J. L M Vermeulen, B. Z. Doulabi, O. Bakker, D. Tibboel, and W. H Lamers
Expression of thyroid hormone receptors A and B in developing rat tissues; evidence for extensive posttranscriptional regulation
J. Mol. Endocrinol., May 1, 2007; 38(5): 523 - 535.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
I. Jones, L. Ng, H. Liu, and D. Forrest
An Intron Control Region Differentially Regulates Expression of Thyroid Hormone Receptor {beta}2 in the Cochlea, Pituitary, and Cone Photoreceptors
Mol. Endocrinol., May 1, 2007; 21(5): 1108 - 1119.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
K. Kristensen, I. Larsson, and S.R. Hansson
Increased cystatin C expression in the pre-eclamptic placenta
Mol. Hum. Reprod., March 1, 2007; 13(3): 189 - 195*.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H.-J. Lee, M. Palkovits, and W. S. Young III
From the Cover: miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation
PNAS, October 17, 2006; 103(42): 15669 - 15674.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
V. Noskova, B. Bottalico, H. Olsson, A. Ehinger, R. Pilka, B. Casslen, and S. R. Hansson
Histamine uptake by human endometrial cells expressing the organic cation transporter EMT and the vesicular monoamine transporter-2
Mol. Hum. Reprod., August 1, 2006; 12(8): 483 - 489.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
S.R. Hansson, Y. Chen, J. Brodszki, M. Chen, E. Hernandez-Andrade, J.M. Inman, O.A. Kozhich, I. Larsson, K. Marsal, P. Medstrand, et al.
Gene expression profiling of human placentas from preeclamptic and normotensive pregnancies
Mol. Hum. Reprod., March 1, 2006; 12(3): 169 - 179.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
C. Venero, A. Guadano-Ferraz, A. I. Herrero, K. Nordstrom, J. Manzano, G. M. de Escobar, J. Bernal, and B. Vennstrom
Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor {alpha}1 can be ameliorated by T3 treatment
Genes & Dev., September 15, 2005; 19(18): 2152 - 2163.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
R. T. Zoeller, R. Bansal, and C. Parris
Bisphenol-A, an Environmental Contaminant that Acts as a Thyroid Hormone Receptor Antagonist in Vitro, Increases Serum Thyroxine, and Alters RC3/Neurogranin Expression in the Developing Rat Brain
Endocrinology, February 1, 2005; 146(2): 607 - 612.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
L Quignodon, C Legrand, N Allioli, A Guadano-Ferraz, J Bernal, J Samarut, and F Flamant
Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development
J. Mol. Endocrinol., October 1, 2004; 33(2): 467 - 476.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
J. Nordengren, R. Pilka, V. Noskova, A. Ehinger, H. Domanski, C. Andersson, G. Hoyer-Hansen, S.R. Hansson, and B. Casslen
Differential localization and expression of urokinase plasminogen activator (uPA), its receptor (uPAR), and its inhibitor (PAI-1) mRNA and protein in endometrial tissue during the menstrual cycle
Mol. Hum. Reprod., September 1, 2004; 10(9): 655 - 663.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
E. Setiawan, D. Owen, L. McCabe, A. Kostaki, M. H. Andrews, and S. G. Matthews
Glucocorticoids Do Not Alter Developmental Expression of Hippocampal or Pituitary Steroid Receptor Coactivator-1 and -2 in the Late Gestation Fetal Guinea Pig
Endocrinology, August 1, 2004; 145(8): 3796 - 3803.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. M. Dupre, H. Guissouma, F. Flamant, I. Seugnet, T. S. Scanlan, J. D. Baxter, J. Samarut, B. A. Demeneix, and N. Becker
Both Thyroid Hormone Receptor (TR){beta}1 and TR{beta}2 Isoforms Contribute to the Regulation of Hypothalamic Thyrotropin-Releasing Hormone
Endocrinology, May 1, 2004; 145(5): 2337 - 2345.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
J. Manzano, B. Morte, T. S. Scanlan, and J. Bernal
Differential Effects of Triiodothyronine and the Thyroid Hormone Receptor {beta}-Specific Agonist GC-1 on Thyroid Hormone Target Genes in the Brain
Endocrinology, December 1, 2003; 144(12): 5480 - 5487.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
H. Heuer and C. A. Mason
Thyroid Hormone Induces Cerebellar Purkinje Cell Dendritic Development via the Thyroid Hormone Receptor {alpha}1
J. Neurosci., November 19, 2003; 23(33): 10604 - 10612.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
B. Bottalico, R. Pilka, I. Larsson, B. Casslen, K. Marsal, and S. R. Hansson
Plasma membrane and vesicular monoamine transporters in normal endometrium and early pregnancy decidua
Mol. Hum. Reprod., July 1, 2003; 9(7): 389 - 394.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
N. Shibusawa, A. N. Hollenberg, and F. E. Wondisford
Thyroid Hormone Receptor DNA Binding Is Required for Both Positive and Negative Gene Regulation
J. Biol. Chem., January 3, 2003; 278(2): 732 - 738.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
A.-M. O'Carroll
Localization of Messenger Ribonucleic Acids for Somatostatin Receptor Subtypes (sstr1-5) in the Rat Adrenal Gland
J. Histochem. Cytochem., January 1, 2003; 51(1): 55 - 60.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. Martinez and F. C. A. Gomes
Neuritogenesis Induced by Thyroid Hormone-treated Astrocytes Is Mediated by Epidermal Growth Factor/Mitogen-activated Protein Kinase-Phosphatidylinositol 3-Kinase Pathways and Involves Modulation of Extracellular Matrix Proteins
J. Biol. Chem., December 13, 2002; 277(51): 49311 - 49318.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
K. Moriyama, T. Tagami, T. Akamizu, T. Usui, M. Saijo, N. Kanamoto, Y. Hataya, A. Shimatsu, H. Kuzuya, and K. Nakao
Thyroid Hormone Action Is Disrupted by Bisphenol A as an Antagonist
J. Clin. Endocrinol. Metab., November 1, 2002; 87(11): 5185 - 5190.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
G. B. Potter, J. M. Zarach, J. M. Sisk, and C. C. Thompson
The Thyroid Hormone-Regulated Corepressor Hairless Associates with Histone Deacetylases in Neonatal Rat Brain
Mol. Endocrinol., November 1, 2002; 16(11): 2547 - 2560.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. L. Coon, E. del Olmo, W. S. Young III, and D. C. Klein
Melatonin Synthesis Enzymes in Macaca mulatta: Focus on Arylalkylamine N-Acetyltransferase (EC 2.3.1.87)
J. Clin. Endocrinol. Metab., October 1, 2002; 87(10): 4699 - 4706.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
N. Vasudevan, S. Ogawa, and D. Pfaff
Estrogen and Thyroid Hormone Receptor Interactions: Physiological Flexibility by Molecular Specificity
Physiol Rev, October 1, 2002; 82(4): 923 - 944.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
T. Cogliati, D. J. Good, M. Haigney, P. Delgado-Romero, M. A. Eckhaus, W. J. Koch, and I. R. Kirsch
Predisposition to Arrhythmia and Autonomic Dysfunction in Nhlh1-Deficient Mice
Mol. Cell. Biol., July 15, 2002; 22(14): 4977 - 4983.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
H. Guissouma, S. M. Dupre, N. Becker, E. Jeannin, I. Seugnet, B. Desvergne, and B. A. Demeneix
Feedback on Hypothalamic TRH Transcription Is Dependent on Thyroid Hormone Receptor N Terminus
Mol. Endocrinol., July 1, 2002; 16(7): 1652 - 1666.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
B. Morte, J. Manzano, T. Scanlan, B. Vennstrom, and J. Bernal
Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism
PNAS, March 19, 2002; 99(6): 3985 - 3989.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
A. C. Bianco, D. Salvatore, B. Gereben, M. J. Berry, and P. R. Larsen
Biochemistry, Cellular and Molecular Biology, and Physiological Roles of the Iodothyronine Selenodeiodinases
Endocr. Rev., February 1, 2002; 23(1): 38 - 89.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
C. Salto, J. M. Kindblom, C. Johansson, Z. Wang, H. Gullberg, K. Nordstrom, A. Mansen, C. Ohlsson, P. Thoren, D. Forrest, et al.
Ablation of TR{alpha}2 and a Concomitant Overexpression of {alpha}1 Yields a Mixed Hypo- and Hyperthyroid Phenotype in Mice
Mol. Endocrinol., December 1, 2001; 15(12): 2115 - 2128.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Itoh, T. Esaki, M. Kaneshige, H. Suzuki, M. Cook, L. Sokoloff, S.-Y. Cheng, and J. Nunez
Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene
PNAS, July 24, 2001; (2001) 171319498.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
P. M. Yen
Physiological and Molecular Basis of Thyroid Hormone Action
Physiol Rev, July 1, 2001; 81(3): 1097 - 1142.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
J. P. H. Burbach, S. M. Luckman, D. Murphy, and H. Gainer
Gene Regulation in the Magnocellular Hypothalamo-Neurohypophysial System
Physiol Rev, July 1, 2001; 81(3): 1197 - 1267.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. K. Hwang, U. M. D'Souza, A. J. Eisch, S. Yajima, C.-H. Lammers, Y. Yang, S.-H. Lee, Y.-M. Kim, E. J. Nestler, and M. M. Mouradian
Dopamine receptor regulating factor, DRRF: A zinc finger transcription factor
PNAS, May 30, 2001; (2001) 121635798.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
F. R. S. Lima, A. Gervais, C. Colin, M. Izembart, V. M. Neto, and M. Mallat
Regulation of Microglial Development: A Novel Role for Thyroid Hormone
J. Neurosci., March 15, 2001; 21(6): 2028 - 2038.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
P. Crisanti, B. Omri, E. J. Hughes, G. Meduri, C. Hery, E. Clauser, C. Jacquemin, and B. Saunier
The Expression of Thyrotropin Receptor in the Brain
Endocrinology, February 1, 2001; 142(2): 812 - 822.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. L. S. Dowling, E. A. Iannacone, and R. T. Zoeller
Maternal Hypothyroidism Selectively Affects the Expression of Neuroendocrine-Specific Protein A Messenger Ribonucleic Acid in the Proliferative Zone of the Fetal Rat Brain Cortex
Endocrinology, January 1, 2001; 142(1): 390 - 399.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
G. Morreale de Escobar, M. Jesús Obregón, and F. Escobar del Rey
Is Neuropsychological Development Related to Maternal Hypothyroidism or to Maternal Hypothyroxinemia?
J. Clin. Endocrinol. Metab., November 1, 2000; 85(11): 3975 - 3987.
[Abstract] [Full Text]

Home page
 J. Neurosci.Home page
A. L. S. Dowling, G. U. Martz, J. L. Leonard, and R. T. Zoeller
Acute Changes in Maternal Thyroid Hormone Induce Rapid and Transient Changes in Gene Expression in Fetal Rat Brain
J. Neurosci., March 15, 2000; 20(6): 2255 - 2265.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
N. Koibuchi, H. Fukuda, and W. W. Chin
Promoter-Specific Regulation of the Brain-Derived Neurotropic Factor Gene by Thyroid Hormone in the Developing Rat Cerebellum
Endocrinology, September 1, 1999; 140(9): 3955 - 3961.
[Abstract] [Full Text]

Home page
 EndocrinologyHome page
A. Dace, G. Sarkissian, L. Schneider, C. Martin-El Yazidi, J. Bonne, A. Margotat, R. Planells, and J. Torresani
Transient Expression of c-erbA{beta}1 Messenger Ribonucleic Acid and {beta}1 Thyroid Hormone Receptor Early in Adipogenesis of Ob 17 Cells
Endocrinology, July 1, 1999; 140(7): 2983 - 2990.
[Abstract] [Full Text]

Home page
 Genes Dev.Home page
S. Göthe, Z. Wang, L. Ng, J. M. Kindblom, A. C. Barros, C. Ohlsson, B. Vennström, and D. Forrest
Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation
Genes & Dev., May 15, 1999; 13(10): 1329 - 1341.
[Abstract] [Full Text]

Home page
 J. Neurosci.Home page
A. Guadano-Ferraz, M. J. Escamez, E. Rausell, and J. Bernal
Expression of Type 2 Iodothyronine Deiodinase in Hypothyroid Rat Brain Indicates an Important Role of Thyroid Hormone in the Development of Specific Primary Sensory Systems
J. Neurosci., May 1, 1999; 19(9): 3430 - 3439.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Y. K. Ng, J. Clark, N. Coulombe, N. Ethier, T. E. Hebert, R. Sullivan, S. Kargman, A. Chateauneuf, N. Tsukamoto, T. McDonald, et al.
Identification of a GABAB Receptor Subunit, gb2, Required for Functional GABAB Receptor Activity
J. Biol. Chem., March 19, 1999; 274(12): 7607 - 7610.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
N. Koibuchi, Y. Liu, H. Fukuda, A. Takeshita, P. M. Yen, and W. W. Chin
ROR{alpha} Augments Thyroid Hormone Receptor-Mediated Transcriptional Activation
Endocrinology, March 1, 1999; 140(3): 1356 - 1364.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
G. Perez-Juste and A. Aranda
The Cyclin-dependent Kinase Inhibitor p27Kip1 Is Involved in Thyroid Hormone-mediated Neuronal Differentiation
J. Biol. Chem., February 19, 1999; 274(8): 5026 - 5031.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
B. Yusta, E. T. Alarid, D. F. Gordon, E. C. Ridgway, and P. L. Mellon
The Thyrotropin {beta}-Subunit Gene Is Repressed by Thyroid Hormone in a Novel Thyrotrope Cell Line, Mouse T{alpha}T1 Cells
Endocrinology, November 1, 1998; 139(11): 4476 - 4482.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Jeannin, D. Robyr, and B. Desvergne
Transcriptional Regulatory Patterns of the Myelin Basic Protein and Malic Enzyme Genes by the Thyroid Hormone Receptors alpha 1 and beta 1
J. Biol. Chem., September 11, 1998; 273(37): 24239 - 24248.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
T. Ben-Hur, B. Rogister, K. Murray, G. Rougon, and M. Dubois-Dalcq
Growth and Fate of PSA-NCAM+ Precursors of the Postnatal Brain
J. Neurosci., August 1, 1998; 18(15): 5777 - 5788.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
C. Pothoulakis, I. Castagliuolo, S. E. Leeman, C.-C. Wang, H. Li, B. J. Hoffman, and E. Mezey
Substance P receptor expression in intestinal epithelium in Clostridium difficile toxin A enteritis in rats
Am J Physiol Gastrointest Liver Physiol, July 1, 1998; 275(1): G68 - G75.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. W. Anderson, R. J. Larson, D. R. Oas, C. R. Sandhofer, H. L. Schwartz, C. N. Mariash, and J. H. Oppenheimer
Chicken Ovalbumin Upstream Promoter-Transcription Factor (COUP-TF) Modulates Expression of the Purkinje Cell Protein-2 Gene. A POTENTIAL ROLE FOR COUP-TF IN REPRESSING PREMATURE THYROID HORMONE ACTION IN THE DEVELOPING BRAIN
J. Biol. Chem., June 26, 1998; 273(26): 16391 - 16399.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
N. Koibuchi and W. W. Chin
ROR{alpha} Gene Expression in the Perinatal Rat Cerebellum: Ontogeny and Thyroid Hormone Regulation
Endocrinology, May 1, 1998; 139(5): 2335 - 2341.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Zimmer, A. M. Zimmer, J. Baffi, T. Usdin, K. Reynolds, M. Konig, M. Palkovits, and E. Mezey
Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene
PNAS, March 3, 1998; 95(5): 2630 - 2635.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
L.-J. Zhu, K. Krempels, C. W. Bardin, A.-M. O'Carroll, and E. Mezey
The Localization of Messenger Ribonucleic Acids for Somatostatin Receptors 1, 2, and 3 in Rat Testis
Endocrinology, January 1, 1998; 139(1): 350 - 357.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol Ind HealthHome page
S. P. Porterfield and L. B. Hendry
Impact of Pcbs On Thyroid Hormone Directed Brain Development
Toxicology and Industrial Health, January 1, 1998; 14(1-2): 103 - 120.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
S. Yajima, C.-H. Lammers, S.-H. Lee, Y. Hara, K. Mizuno, and M. M. Mouradian
Cloning and Characterization of Murine Glial Cell-Derived Neurotrophic Factor Inducible Transcription Factor (MGIF)
J. Neurosci., November 15, 1997; 17(22): 8657 - 8666.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. Farsetti, J. Lazar, M. Phyillaier, R. Lippoldt, A. Pontecorvi, and V. M. Nikodem
Active Repression by Thyroid Hormone Receptor Splicing Variant {alpha}2 Requires Specific Regulatory Elements in the Context of Native Triiodothyronine-Regulated Gene Promoters
Endocrinology, November 1, 1997; 138(11): 4705 - 4712.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
R. E. M. Scott, X. S. Wu-Peng, P. M. Yen, W. W. Chin, and D. W. Pfaff
Interactions of Estrogen- and Thyroid Hormone Receptors on a Progesterone Receptor Estrogen Response Element (ERE) Sequence: a Comparison with the Vitellogenin A2 Consensus ERE
Mol. Endocrinol., October 1, 1997; 11(11): 1581 - 1592.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. C. Thompson and M. C. Bottcher
The product of a thyroid hormone-responsive gene interacts with thyroid hormone receptors
PNAS, August 5, 1997; 94(16): 8527 - 8532.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
J. H. Oppenheimer and H. L. Schwartz
Molecular Basis of Thyroid Hormone-Dependent Brain Development
Endocr. Rev., August 1, 1997; 18(4): 462 - 475.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
R. T. Zoeller, D. L. Fletcher, O. Butnariu, C. A. Lowry, and F. L. Moore
N-Ethylmaleimide (NEM) Can Significantly Improve In Situ Hybridization Results Using 35S-labeled Oligodeoxynucleotide or Complementary RNA Probes
J. Histochem. Cytochem., July 1, 1997; 45(7): 1035 - 1042.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. M. White, T. Takeda, L. J. DeGroot, K. Stefansson, and B. G. W. Arnason
beta -Trace Gene Expression Is Regulated by a Core Promoter and a Distal Thyroid Hormone Response Element
J. Biol. Chem., May 30, 1997; 272(22): 14387 - 14393.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. A. Eglitis and E. Mezey
Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice
PNAS, April 15, 1997; 94(8): 4080 - 4085.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
T. Nagasawa, S. Suzuki, T. Takeda, and L. J. DeGroot
Thyroid Hormone Receptor {beta}1 Expression in Developing Mouse Limbs and Face
Endocrinology, March 1, 1997; 138(3): 1276 - 1281.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. S. Moriscot, M. R. Sayen, R. Hartong, P. Wu, and W. H. Dillmann
Transcription of the Rat Sarcoplasmic Reticulum Ca2+ Adenosine Triphosphatase Gene Is Increased by 3,5,3'-Triiodothyronine Receptor Isoform-Specific Interactions with the Myocyte-Specific Enhancer Factor-2a
Endocrinology, January 1, 1997; 138(1): 26 - 32.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
C. C. Thompson
Thyroid Hormone-Responsive Genes in Developing Cerebellum Include a Novel Synaptotagmin and a hairless Homolog
J. Neurosci., December 15, 1996; 16(24): 7832 - 7840.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Kelley, J. Turner, and T. Reh
Ligands of steroid/thyroid receptors induce cone photoreceptors in vertebrate retina
Development, January 11, 1995; 121(11): 3777 - 3785.
[Abstract] [PDF]

Home page
 NEJMHome page
G. A. Brent
The Molecular Basis of Thyroid Hormone Action
N. Engl. J. Med., September 29, 1994; 331(13): 847 - 853.
[Full Text]

Home page
 DevelopmentHome page
B. Barres, M. Lazar, and M. Raff
A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development
Development, January 5, 1994; 120(5): 1097 - 1108.
[Abstract] [PDF]

Home page
 DevelopmentHome page
J. Truman, W. Talbot, S. Fahrbach, and D. Hogness
Ecdysone receptor expression in the CNS correlates with stage-specific responses to ecdysteroids during Drosophila and Manduca development
Development, January 1, 1994; 120(1): 219 - 234.
[Abstract] [PDF]

Home page
 DevelopmentHome page
S. Robinow, W. S. Talbot, D. S. Hogness, and J. W. Truman
Programmed cell death in the Drosophila CNS is ecdysone-regulated and coupled with a specific ecdysone receptor isoform
Development, December 1, 1993; 119(4): 1251 - 1259.
[Abstract] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. K. Hwang, U. M. D'Souza, A. J. Eisch, S. Yajima, C.-H. Lammers, Y. Yang, S.-H. Lee, Y.-M. Kim, E. J. Nestler, and M. M. Mouradian
Dopamine receptor regulating factor, DRRF: A zinc finger transcription factor
PNAS, June 19, 2001; 98(13): 7558 - 7563.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Itoh, T. Esaki, M. Kaneshige, H. Suzuki, M. Cook, L. Sokoloff, S.-Y. Cheng, and J. Nunez
Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene
PNAS, August 14, 2001; 98(17): 9913 - 9918.
[Abstract] [Full Text] [PDF]


-
-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2009 by Society for Neuroscience ONLINE ISSN: 1529-2401
-