Disparity sensitivity of neurons in monkey extrastriate area MST

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):
Year:		Vol:		Page:

HOME | SEARCH | ARCHIVE | SUBSCRIBE | CONTACT | HELP

This Article

Full Text (PDF)

Submit an eLetter

Alert me when this article is cited

Alert me when eLetters are posted

Alert me if a correction is posted

Citation Map

Services

Email this article to a friend

Similar articles in this journal

Similar articles in Web of Science

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Web of Science (145)

Citing Articles via Google Scholar

Google Scholar

Articles by Roy, J. P.

Articles by Wurtz, R. H.

Search for Related Content

PubMed

PubMed Citation

Articles by Roy, J. P.

Articles by Wurtz, R. H.

Previous Article | Next Article

Journal of Neuroscience, Vol 12, 2478-2492, Copyright © 1992 by Society for Neuroscience

ARTICLE

Disparity sensitivity of neurons in monkey extrastriate area MST

JP Roy, H Komatsu and RH Wurtz
Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, Maryland 20892.
We tested the disparity sensitivity of neurons from the medial superior temporal area (MST) in awake behaving monkeys. While the monkey looked at a fixation spot on a screen in front of it, random dot stimuli moved in the preferred direction of the cell under study, and the disparity of the dots made the stimuli appear to move in a frontoparallel plane in front of, on, or behind the screen. Over 90% of the 272 neurons studied were sensitive to the disparity of the visual stimulus. Of those disparity-sensitive cells, 95% were most responsive either to near stimuli (stimuli with crossed disparities appearing to move in front of the screen) or to far stimuli (stimuli with uncrossed disparities appearing to move behind the screen). In a smaller sample of the disparity-sensitive cells, we found cells whose preferred direction of stimulus motion reversed as the disparity of the stimulus reversed. For example, a cell that responded best to rightward motion for near stimuli responded best to leftward motion for far stimuli. We found that 40% of the disparity-sensitive cells had this disparity- dependent direction selectivity. This disparity-dependent direction selectivity was maintained over the entire range of speeds tested (6-56 degrees/sec). We tested whether the disparity sensitivity of the neurons indicated the distance of the stimulus from the screen where the monkey was fixating (relative depth) or the distance of the stimulus from the monkey (absolute depth) by having the monkey fixate at different depths in front of or behind the screen. For most MST neurons, the changes in vergence did not alter the disparity response, indicating that the disparity sensitivity of these neurons conveyed information on depth relative to the plane of fixation. We conclude that the disparity characteristics of cells in the dorsomedial MST are those expected of a system serving primarily coarse rather than fine stereopsis. The correlation between disparity selectivity and direction selectivity in these neurons, as well as their other properties, suggests a role in signaling the direction of self-motion of the observer through the environment.

This article has been cited by other articles:

S. Ferraina, E. Brunamonti, M. A. Giusti, S. Costa, A. Genovesio, and R. Caminiti
Reaching in Depth: Hand Position Dominates over Binocular Eye Position in the Rostral Superior Parietal Lobule
J. Neurosci., September 16, 2009; 29(37): 11461 - 11470.
[Abstract] [Full Text] [PDF]

S. Srivastava, G. A. Orban, P. A. De Maziere, and P. Janssen
A Distinct Representation of Three-Dimensional Shape in Macaque Anterior Intraparietal Area: Fast, Metric, and Coarse
J. Neurosci., August 26, 2009; 29(34): 10613 - 10626.
[Abstract] [Full Text] [PDF]

P. Neri and D. M. Levi
Evidence for Joint Encoding of Motion and Disparity in Human Visual Perception
J Neurophysiol, December 1, 2008; 100(6): 3117 - 3133.
[Abstract] [Full Text] [PDF]

S. A. Chowdhury, D. L. Christiansen, M. L. Morgan, and G. C. DeAngelis
Effect of Vertical Disparities on Depth Representation in Macaque Monkeys: MT Physiology and Behavior
J Neurophysiol, February 1, 2008; 99(2): 876 - 887.
[Abstract] [Full Text] [PDF]

A. Takemura, Y. Murata, K. Kawano, and F. A. Miles
Deficits in Short-Latency Tracking Eye Movements after Chemical Lesions in Monkey Cortical Areas MT and MST
J. Neurosci., January 17, 2007; 27(3): 529 - 541.
[Abstract] [Full Text] [PDF]

T. Uka and G. C. DeAngelis
Linking neural representation to function in stereoscopic depth perception: roles of the middle temporal area in coarse versus fine disparity discrimination.
J. Neurosci., June 21, 2006; 26(25): 6791 - 6802.
[Abstract] [Full Text] [PDF]

T. Uka, S. Tanabe, M. Watanabe, and I. Fujita
Neural Correlates of Fine Depth Discrimination in Monkey Inferior Temporal Cortex
J. Neurosci., November 16, 2005; 25(46): 10796 - 10802.
[Abstract] [Full Text] [PDF]

D. A. Hinkle and C. E. Connor
Quantitative Characterization of Disparity Tuning in Ventral Pathway Area V4
J Neurophysiol, October 1, 2005; 94(4): 2726 - 2737.
[Abstract] [Full Text] [PDF]

F. Bremmer
Navigation in space - the role of the macaque ventral intraparietal area
J. Physiol., July 1, 2005; 566(1): 29 - 35.
[Abstract] [Full Text] [PDF]

T. Akao, M. J. Mustari, J. Fukushima, S. Kurkin, and K. Fukushima
Discharge Characteristics of Pursuit Neurons in MST During Vergence Eye Movements
J Neurophysiol, May 1, 2005; 93(5): 2415 - 2434.
[Abstract] [Full Text] [PDF]

P. Neri, H. Bridge, and D. J. Heeger
Stereoscopic Processing of Absolute and Relative Disparity in Human Visual Cortex
J Neurophysiol, September 1, 2004; 92(3): 1880 - 1891.
[Abstract] [Full Text] [PDF]

A. Genovesio and S. Ferraina
Integration of Retinal Disparity and Fixation-Distance Related Signals Toward an Egocentric Coding of Distance in the Posterior Parietal Cortex of Primates
J Neurophysiol, June 1, 2004; 91(6): 2670 - 2684.
[Abstract] [Full Text] [PDF]

X. Xu, C. E. Collins, P. M. Kaskan, I. Khaytin, J. H. Kaas, and V. A. Casagrande
Optical imaging of visually evoked responses in prosimian primates reveals conserved features of the middle temporal visual area
PNAS, February 24, 2004; 101(8): 2566 - 2571.
[Abstract] [Full Text] [PDF]

M. Wei, G. C. DeAngelis, and D. E. Angelaki
Do Visual Cues Contribute to the Neural Estimate of Viewing Distance Used by the Oculomotor System?
J. Neurosci., September 10, 2003; 23(23): 8340 - 8350.
[Abstract] [Full Text] [PDF]

Z. Kourtzi, M. Erb, W. Grodd, and H. H. Bulthoff
Representation of the Perceived 3-D Object Shape in the Human Lateral Occipital Complex
Cereb Cortex, September 1, 2003; 13(9): 911 - 920.
[Abstract] [Full Text] [PDF]

T. Uka and G. C. DeAngelis
Contribution of Middle Temporal Area to Coarse Depth Discrimination: Comparison of Neuronal and Psychophysical Sensitivity
J. Neurosci., April 15, 2003; 23(8): 3515 - 3530.
[Abstract] [Full Text] [PDF]

G. C. DeAngelis and T. Uka
Coding of Horizontal Disparity and Velocity by MT Neurons in the Alert Macaque
J Neurophysiol, February 1, 2003; 89(2): 1094 - 1111.
[Abstract] [Full Text] [PDF]

K. V. Shenoy, J. A. Crowell, and R. A. Andersen
Pursuit Speed Compensation in Cortical Area MSTd
J Neurophysiol, November 1, 2002; 88(5): 2630 - 2647.
[Abstract] [Full Text] [PDF]

M. T. Froehler and C. J. Duffy
Cortical Neurons Encoding Path and Place: Where You Go Is Where You Are
Science, March 29, 2002; 295(5564): 2462 - 2465.
[Abstract] [Full Text] [PDF]

P. Janssen, R. Vogels, Y. Liu, and G. A. Orban
Macaque Inferior Temporal Neurons Are Selective for Three-Dimensional Boundaries and Surfaces
J. Neurosci., December 1, 2001; 21(23): 9419 - 9429.
[Abstract] [Full Text] [PDF]

D. L. Adams and S. Zeki
Functional Organization of Macaque V3 for Stereoscopic Depth
J Neurophysiol, November 1, 2001; 86(5): 2195 - 2203.
[Abstract] [Full Text] [PDF]

J. V. Dodd, K. Krug, B. G. Cumming, and A. J. Parker
Perceptually Bistable Three-Dimensional Figures Evoke High Choice Probabilities in Cortical Area MT
J. Neurosci., July 1, 2001; 21(13): 4809 - 4821.
[Abstract] [Full Text] [PDF]

A. Takemura, Y. Inoue, K. Kawano, C. Quaia, and F. A. Miles
Single-Unit Activity in Cortical Area MST Associated With Disparity-Vergence Eye Movements: Evidence for Population Coding
J Neurophysiol, May 1, 2001; 85(5): 2245 - 2266.
[Abstract] [Full Text] [PDF]

C. Busettini, E. J. Fitzgibbon, and F. A. Miles
Short-Latency Disparity Vergence in Humans
J Neurophysiol, March 1, 2001; 85(3): 1129 - 1152.
[Abstract] [Full Text] [PDF]

H. Tanaka, T. Uka, K. Yoshiyama, M. Kato, and I. Fujita
Processing of Shape Defined by Disparity in Monkey Inferior Temporal Cortex
J Neurophysiol, February 1, 2001; 85(2): 735 - 744.
[Abstract] [Full Text] [PDF]

U. D. Upadhyay, W. K. Page, and C. J. Duffy
MST Responses to Pursuit Across Optic Flow With Motion Parallax
J Neurophysiol, August 1, 2000; 84(2): 818 - 826.
[Abstract] [Full Text] [PDF]

A.L. Paradis, V. Cornilleau-Peres, J. Droulez, P.F. Van de Moortele, E. Lobel, A. Berthoz, D. Le Bihan, and J.B. Poline
Visual Perception of Motion and 3-D Structure from Motion: an fMRI Study
Cereb Cortex, August 1, 2000; 10(8): 772 - 783.
[Abstract] [Full Text] [PDF]

T. Uka, H. Tanaka, K. Yoshiyama, M. Kato, and I. Fujita
Disparity Selectivity of Neurons in Monkey Inferior Temporal Cortex
J Neurophysiol, July 1, 2000; 84(1): 120 - 132.
[Abstract] [Full Text] [PDF]

A. Nieder and H. Wagner
Horizontal-Disparity Tuning of Neurons in the Visual Forebrain of the Behaving Barn Owl
J Neurophysiol, May 1, 2000; 83(5): 2967 - 2979.
[Abstract] [Full Text] [PDF]

S. Ferraina, M. Pare, and R. H. Wurtz
Disparity Sensitivity of Frontal Eye Field Neurons
J Neurophysiol, January 1, 2000; 83(1): 625 - 629.
[Abstract] [Full Text] [PDF]

S. Grossberg, E. Mingolla, and C. Pack
A Neural Model of Motion Processing and Visual Navigation by Cortical Area MST
Cereb Cortex, December 1, 1999; 9(8): 878 - 895.
[Abstract] [Full Text] [PDF]

S. Eifuku and R. H. Wurtz
Response to Motion in Extrastriate Area MSTl: Disparity Sensitivity
J Neurophysiol, November 1, 1999; 82(5): 2462 - 2475.
[Abstract] [Full Text] [PDF]

P. Janssen, R. Vogels, and G. A. Orban
Macaque inferior temporal neurons are selective for disparity-defined three-dimensional shapes
PNAS, July 6, 1999; 96(14): 8217 - 8222.
[Abstract] [Full Text] [PDF]

K. V. Shenoy, D. C. Bradley, and R. A. Andersen
Influence of Gaze Rotation on the Visual Response of Primate MSTd Neurons
J Neurophysiol, June 1, 1999; 81(6): 2764 - 2786.
[Abstract] [Full Text] [PDF]

V. Chaturvedi and J. A.�M. van Gisbergen
Perturbation of Combined Saccade-Vergence Movements by Microstimulation in Monkey Superior Colliculus
J Neurophysiol, May 1, 1999; 81(5): 2279 - 2296.
[Abstract] [Full Text] [PDF]

K. Zhang and T. J. Sejnowski
A Theory of Geometric Constraints on Neural Activity for Natural Three-Dimensional Movement
J. Neurosci., April 15, 1999; 19(8): 3122 - 3145.
[Abstract] [Full Text] [PDF]

G. C. DeAngelis and W. T. Newsome
Organization of Disparity-Selective Neurons in Macaque Area MT
J. Neurosci., February 15, 1999; 19(4): 1398 - 1415.
[Abstract] [Full Text] [PDF]

J. A. Perrone and L. S. Stone
Emulating the Visual Receptive-Field Properties of MST Neurons with a Template Model of Heading Estimation
J. Neurosci., August 1, 1998; 18(15): 5958 - 5975.
[Abstract] [Full Text] [PDF]

R. S. Zemel and T. J. Sejnowski
A Model for Encoding Multiple Object Motions and Self-Motion in Area MST of Primate Visual Cortex
J. Neurosci., January 1, 1998; 18(1): 531 - 547.
[Abstract] [Full Text] [PDF]

Y. M. Chino, E. L. Smith III, S. Hatta, and H. Cheng
Postnatal Development of Binocular Disparity Sensitivity in Neurons of the Primate Visual Cortex
J. Neurosci., January 1, 1997; 17(1): 296 - 307.
[Abstract] [Full Text] [PDF]

M. Lappe, F. Bremmer, M. Pekel, A. Thiele, and K.-P. Hoffmann
Optic Flow Processing in Monkey STS: A Theoretical and Experimental Approach
J. Neurosci., October 1, 1996; 16(19): 6265 - 6285.
[Abstract] [Full Text] [PDF]