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Journal of Neuroscience, Vol 13, 1202-1226, Copyright © 1993 by Society for Neuroscience


ARTICLE

A PET study of visuospatial attention

M Corbetta, FM Miezin, GL Shulman and SE Petersen
Department of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 63110.

Positron emission tomography (PET) was used to identify the neural systems involved in shifting spatial attention to visual stimuli in the left or right visual field along foveofugal or foveocentric directions. Psychophysical evidence indicated that stimuli at validly cued locations were responded to faster than stimuli at invalidly cued locations. Reaction times to invalid probes were faster when they were presented in the same than in the opposite direction of an ongoing attention movement. PET evidence indicated that superior parietal and superior frontal cortex were more active when attention was shifted to peripheral locations than when maintained at the center of gaze. Both regions encoded the visual field and not the direction of an attention shift. In the right superior parietal lobe, two distinct responses were localized for attention to left and right visual field. Finally, the superior parietal region was active when peripheral locations were selected on the basis of cognitive or sensory cues independent of the execution of an overt response. The frontal region was active only when responses were made to stimuli at selected peripheral locations. These findings indicate that parietal and frontal regions control different aspects of spatial selection. The functional asymmetry in superior parietal cortex may be relevant for the pathophysiology of unilateral neglect.


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P. C. Fletcher and R. N. A. Henson
Frontal lobes and human memory: Insights from functional neuroimaging
Brain, May 1, 2001; 124(5): 849 - 881.
[Abstract] [Full Text] [PDF]


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J. Neurosci.Home page
H. Peuskens, S. Sunaert, P. Dupont, P. Van Hecke, and G. A. Orban
Human Brain Regions Involved in Heading Estimation
J. Neurosci., April 1, 2001; 21(7): 2451 - 2461.
[Abstract] [Full Text] [PDF]


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NeurologyHome page
A.H. Lockwood, D.S. Wack, R.F. Burkard, M.L. Coad, S.A. Reyes, S.A. Arnold, and R.J. Salvi
The functional anatomy of gaze-evoked tinnitus and sustained lateral gaze
Neurology, February 27, 2001; 56(4): 472 - 480.
[Abstract] [Full Text] [PDF]


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Cereb CortexHome page
J.T. Coull, A.C. Nobre, and C.D. Frith
The Noradrenergic {{alpha}}2 Agonist Clonidine Modulates Behavioural and Neuroanatomical Correlates of Human Attentional Orienting and Alerting
Cereb Cortex, January 1, 2001; 11(1): 73 - 84.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
G. L. Shulman, J. M. Ollinger, M. Linenweber, S. E. Petersen, and M. Corbetta
Multiple neural correlates of detection in the human brain
PNAS, December 22, 2000; (2000) 21381198.
[Abstract] [Full Text]


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Cereb CortexHome page
J.-M. Hopf, S. J. Luck, M. Girelli, T. Hagner, G. R. Mangun, H. Scheich, and H.-J. Heinze
Neural Sources of Focused Attention in Visual Search
Cereb Cortex, December 1, 2000; 10(12): 1233 - 1241.
[Abstract] [Full Text] [PDF]


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BrainHome page
R. J. Perry and S. Zeki
The neurology of saccades and covert shifts in spatial attention: An event-related fMRI study
Brain, November 1, 2000; 123(11): 2273 - 2288.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
P. M. Greenwood, T. Sunderland, J. L. Friz, and R. Parasuraman
Genetics and visual attention: Selective deficits in healthy adult carriers of the varepsilon 4 allele of the apolipoprotein E gene
PNAS, October 10, 2000; 97(21): 11661 - 11666.
[Abstract] [Full Text] [PDF]


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J. Neurophysiol.Home page
K. Kurata, T. Tsuji, S. Naraki, M. Seino, and Y. Abe
Activation of the Dorsal Premotor Cortex and Pre-Supplementary Motor Area of Humans During an Auditory Conditional Motor Task
J Neurophysiol, September 1, 2000; 84(3): 1667 - 1672.
[Abstract] [Full Text] [PDF]


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ScienceHome page
E. Macaluso, C. D. Frith, and J. Driver
Modulation of Human Visual Cortex by Crossmodal Spatial Attention
Science, August 18, 2000; 289(5482): 1206 - 1208.
[Abstract] [Full Text]


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ScienceHome page
J. Duncan, R. J. Seitz, J. Kolodny, D. Bor, H. Herzog, A. Ahmed, F. N. Newell, and H. Emslie
A Neural Basis for General Intelligence
Science, July 21, 2000; 289(5478): 457 - 460.
[Abstract] [Full Text]


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Proc. Natl. Acad. Sci. USAHome page
B. J. Casey, K. M. Thomas, T. F. Welsh, R. D. Badgaiyan, C. H. Eccard, J. R. Jennings, and E. A. Crone
Dissociation of response conflict, attentional selection, and expectancy with functional magnetic resonance imaging
PNAS, July 18, 2000; 97(15): 8728 - 8733.
[Abstract] [Full Text] [PDF]


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Cereb CortexHome page
R. Vandenberghe, J. Duncan, K. M. Arnell, S. J. Bishop, N. J. Herrod, A. M. Owen, P. S. Minhas, P. Dupont, J. D. Pickard, and G. A. Orban
Maintaining and Shifting Attention within Left or Right Hemifield
Cereb Cortex, July 1, 2000; 10(7): 706 - 713.
[Abstract] [Full Text] [PDF]


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BrainHome page
I. H. Jenkins, M. Jahanshahi, M. Jueptner, R. E. Passingham, and D. J. Brooks
Self-initiated versus externally triggered movements: II. The effect of movement predictability on regional cerebral blood flow
Brain, June 1, 2000; 123(6): 1216 - 1228.
[Abstract] [Full Text] [PDF]


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J. Neurophysiol.Home page
E. Macaluso, C. Frith, and J. Driver
Selective Spatial Attention in Vision and Touch: Unimodal and Multimodal Mechanisms Revealed by PET
J Neurophysiol, May 1, 2000; 83(5): 3062 - 3075.
[Abstract] [Full Text] [PDF]


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J. Neurophysiol.Home page
M. C. Davidson and R. T. Marrocco
Local Infusion of Scopolamine Into Intraparietal Cortex Slows Covert Orienting in Rhesus Monkeys
J Neurophysiol, March 1, 2000; 83(3): 1536 - 1549.
[Abstract] [Full Text] [PDF]


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J. Neurosci.Home page
A. Bischoff-Grethe, S. M. Proper, H. Mao, K. A. Daniels, and G. S. Berns
Conscious and Unconscious Processing of Nonverbal Predictability in Wernicke's Area
J. Neurosci., March 1, 2000; 20(5): 1975 - 1981.
[Abstract] [Full Text] [PDF]


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BrainHome page
L. Y. Deouell, S. Bentin, and N. Soroker
Electrophysiological evidence for an early (pre-attentive) information processing deficit in patients with right hemisphere damage and unilateral neglect
Brain, February 1, 2000; 123(2): 353 - 365.
[Abstract] [Full Text] [PDF]


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Cereb CortexHome page
W. Vanduffel, R. B.H. Tootell, and G. A. Orban
Attention-dependent Suppression of Metabolic Activity in the Early Stages of the Macaque Visual System
Cereb Cortex, February 1, 2000; 10(2): 109 - 126.
[Abstract] [Full Text] [PDF]


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J Learn DisabilHome page
T. A. Sandson, K. J. Bachna, and M. D. Morin
Right Hemisphere Dysfunction in ADHD: Visual Hemispatial Inattention and Clinical Subtype
J Learn Disabil, January 1, 2000; 33(1): 83 - 90.
[Abstract] [PDF]



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