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Journal of Neuroscience, Vol 13, 1227-1243, Copyright © 1993 by Society for Neuroscience
Visuospatial versus visuomotor activity in the premotor and prefrontal cortex of a primate
G di Pellegrino and SP Wise
Laboratory of Neurophysiology, National Institute of Mental Health, Poolesville, Maryland 20837.
When visuospatial stimuli instruct a limb movement, the stimulus can be
said to have both sensory and sensorimotor aspects. We studied the premotor
and prefrontal areas of a rhesus monkey in order to identify neuronal
activity related to the motor (or instructional) aspects of such stimuli. A
rhesus monkey chose limb-movement targets according to one of two rules:
(1) visuospatial stimuli instructed and triggered a limb movement toward
their locations or (2) identical stimuli triggered a movement toward a
predetermined target regardless of their location. Gaze and head fixation
assured that each stimulus appeared at a constant location in both
retinocentric and craniocentric coordinates, as well as in allocentric
space. The task required that the spatial location cued by certain stimuli
had to be either remembered or attended after stimulus presentation and
before movement. Thus, the visuospatial information presented under one
rule differed from that presented under the other only in its motor
(instructional) significance and not in its attentional, spatial, mnemonic,
or strictly sensory aspects. We could thereby test and confirm the
hypothesis that the motor significance of visuospatial cues should commonly
affect neuronal activity in the premotor cortex, but less commonly do so in
the prefrontal cortex.
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|
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|
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|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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[Full Text]
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
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[Full Text]
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|
|
|
|
|
|
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[Full Text]
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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[Full Text]
[PDF]
|
|
|
|
|
|
|
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[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
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[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
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J Neurophysiol,
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83(4):
2355 - 2373.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Durstewitz, J. K. Seamans, and T. J. Sejnowski
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J Neurophysiol,
March 1, 2000;
83(3):
1733 - 1750.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Sawaguchi and I. Yamane
Properties of Delay-Period Neuronal Activity in the Monkey Dorsolateral Prefrontal Cortex During a Spatial Delayed Matching-to-Sample Task
J Neurophysiol,
November 1, 1999;
82(5):
2070 - 2080.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Durstewitz, M. Kelc, and O. Gunturkun
A Neurocomputational Theory of the Dopaminergic Modulation of Working Memory Functions
J. Neurosci.,
April 1, 1999;
19(7):
2807 - 2822.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M.T.V. Johnson, J. D. Coltz, M. C. Hagen, and T. J. Ebner
Visuomotor Processing as Reflected in the Directional Discharge of Premotor and Primary Motor Cortex Neurons
J Neurophysiol,
February 1, 1999;
81(2):
875 - 894.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Rainer, W. F. Asaad, and E. K. Miller
Memory fields of neurons in the primate prefrontal cortex
PNAS,
December 8, 1998;
95(25):
15008 - 15013.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. A. Basso and R. H. Wurtz
Modulation of Neuronal Activity in Superior Colliculus by Changes in Target Probability
J. Neurosci.,
September 15, 1998;
18(18):
7519 - 7534.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Boussaoud, C. Jouffrais, and F. Bremmer
Eye Position Effects on the Neuronal Activity of Dorsal Premotor Cortex in the Macaque Monkey
J Neurophysiol,
September 1, 1998;
80(3):
1132 - 1150.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. L. Moody, S. P. Wise, G. di Pellegrino, and D. Zipser
A Model That Accounts for Activity in Primate Frontal Cortex during a Delayed Matching-to-Sample Task
J. Neurosci.,
January 1, 1998;
18(1):
399 - 410.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. H. Scott, L. E. Sergio, and J. F. Kalaska
Reaching Movements With Similar Hand Paths but Different Arm Orientations. II. Activity of Individual Cells in Dorsal Premotor Cortex and Parietal Area 5
J Neurophysiol,
November 1, 1997;
78(5):
2413 - 2426.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W. A. Suzuki, E. K. Miller, and R. Desimone
Object and Place Memory in the Macaque Entorhinal Cortex
J Neurophysiol,
August 1, 1997;
78(2):
1062 - 1081.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. C. Rao, G. Rainer, and E. K. Miller
Integration of What and Where in the Primate Prefrontal Cortex
Science,
May 2, 1997;
276(5313):
821 - 824.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
G. R. Fink, R. S. J. Frackowiak, U. Pietrzyk, and R. E. Passingham
Multiple Nonprimary Motor Areas in the Human Cortex
J Neurophysiol,
April 1, 1997;
77(4):
2164 - 2174.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Zhang, A. Riehle, J. Requin, and S. Kornblum
Dynamics of Single Neuron Activity in Monkey Primary Motor Cortex Related to Sensorimotor Transformation
J. Neurosci.,
March 15, 1997;
17(6):
2227 - 2246.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Shen and G. E. Alexander
Neural Correlates of a Spatial Sensory-To-Motor Transformation in Primary Motor Cortex
J Neurophysiol,
March 1, 1997;
77(3):
1171 - 1194.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Shen and G. E. Alexander
Preferential Representation of Instructed Target Location Versus Limb Trajectory in Dorsal Premotor Area
J Neurophysiol,
March 1, 1997;
77(3):
1195 - 1212.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Desimone
Neural mechanisms for visual memory and their role in attention
PNAS,
November 26, 1996;
93(24):
13494 - 13499.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. K. Miller, C. A. Erickson, and R. Desimone
Neural Mechanisms of Visual Working Memory in Prefrontal Cortex of the Macaque
J. Neurosci.,
August 15, 1996;
16(16):
5154 - 5167.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. L. Chen and S. P. Wise
Evolution of Directional Preferences in the Supplementary Eye Field during Acquisition of Conditional Oculomotor Associations
J. Neurosci.,
May 1, 1996;
16(9):
3067 - 3081.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
