 |
 Previous Article | Next Article 
Journal of Neuroscience, Vol 14, 1496-1506, Copyright © 1994 by Society for Neuroscience
Peripheral influences on the size and organization of somatotopic representations in the fetal rat cortex
HP Killackey, NL Chiaia, CA Bennett-Clarke, M Eck and RW Rhoades
Department of Psychobiology, University of California at Irvine 92717.
Nerve lesions at different fetal ages and on the day of birth were used to
determine the role of the periphery in establishing territories devoted to
representations of different portions of the body surface in rat
somatosensory cortex. Transection of the infraorbital nerve (ION), the
trigeminal branch that supplies the whisker pad, resulted in a significant
reduction in the area within the primary somatosensory cortex devoted to
the representation of the mystacial vibrissae in fetal, but not newborn,
rats. Such lesions in fetal, but not neonatal, rats also resulted in
significant increases in the cortical area devoted to the representation of
the lower lip and jaw. There was a significant positive correlation between
the reduction in the vibrissae representation and the expansion of that of
the lower lip and jaw. Damage to the ION in either neonatal or fetal rats
failed to increase significantly the amount of cortex devoted to the
representation of the forepaw. These results indicate that the primary
afferent innervation of the periphery does influence the amounts of cortex
devoted to representations of different parts of the body surface and that
the representation of one region can expand significantly when that of
another body part is reduced.
This article has been cited by other articles:
|
|
|
|
 
F. Oury, Y. Murakami, J.-S. Renaud, M. Pasqualetti, P. Charnay, S.-Y. Ren, and F. M. Rijli
Hoxa2- and Rhombomere-Dependent Development of the Mouse Facial Somatosensory Map
Science,
September 8, 2006;
313(5792):
1408 - 1413.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Jain, P. S. Diener, J.-O. Coq, and J. H. Kaas
Patterned Activity via Spinal Dorsal Quadrant Inputs Is Necessary for the Formation of Organized Somatosensory Maps
J. Neurosci.,
November 12, 2003;
23(32):
10321 - 10330.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. P. Pluto, R. D. Lane, N. L. Chiaia, A. S. Stojic, and R. W. Rhoades
Role of Development in Reorganization of the SI Forelimb-Stump Representation in Fetally, Neonatally, and Adult Amputated Rats
J Neurophysiol,
September 1, 2003;
90(3):
1842 - 1851.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
I. H.M. Smart, C. Dehay, P. Giroud, M. Berland, and H. Kennedy
Unique Morphological Features of the Proliferative Zones and Postmitotic Compartments of the Neural Epithelium Giving Rise to Striate and Extrastriate Cortex in the Monkey
Cereb Cortex,
January 1, 2002;
12(1):
37 - 53.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Gaillard and M. Roger
Early Commitment of Embryonic Neocortical Cells to Develop Area-specific Thalamic Connections
Cereb Cortex,
May 1, 2000;
10(5):
443 - 453.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Gitton, M. Cohen-Tannoudji, and M. Wassef
Role of Thalamic Axons in the Expression of H-2Z1, a Mouse Somatosensory Cortex Specific Marker
Cereb Cortex,
September 1, 1999;
9(6):
611 - 620.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Holmberg, J. Schouenborg, Y.-B. Yu, and H.-R. Weng
Developmental Adaptation of Rat Nociceptive Withdrawal Reflexes after Neonatal Tendon Transfer
J. Neurosci.,
March 15, 1997;
17(6):
2071 - 2078.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
