WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience Synaptic Systems Antibody Company
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shimatani, Y.
Right arrow Articles by Katagiri, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shimatani, Y.
Right arrow Articles by Katagiri, Y.

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 15, 6489-6497, Copyright © 1995 by Society for Neuroscience

ARTICLE

Light removes inactivation of the A-type potassium channels in scallop hyperpolarizing photoreceptors

Y Shimatani and Y Katagiri
Department of Physiology, Tokyo Women's Medical College, Japan.

The properties of light-activated and voltage dependent conductances in the hyperpolarizing photoreceptors of the isolated retina of the giant scallop (Patinopecten yessoensis) have been studied in whole-cell voltage-clamp recordings. Resting membrane potential of the cells was - 35 to -60 mV in the dark. Large outward current was maintained during illumination when the cell was voltage clamped at the resting potential. Previous reports have shown that the hyperpolarizing response to light and the light-activated outward current are mediated by an increase of a conductance of K+ channels in the plasma membrane (Gorman and McReynolds, 1974; Gomez and Nasi, 1994a). This report shows that the light-activated K+ channels of this photoreceptor cell generate the voltage-dependent transient outward current in response to depolarizing voltage steps in the dark. The characteristic of this current resembles the typical voltage-dependent transient current (A- current) of molluscan neurons in the kinetics of activation and inactivation, and in the blockage by 4-aminopyridine (4-AP). However, the voltage-dependent transient current during illumination becomes a flat stable form which inactivation process disappeared. We report here that light removes inactivation of the K+ channels which generate the voltage-dependent transient outward currents in the dark.


This article has been cited by other articles:


Home page
 J. Gen. Physiol.Home page
M. del Pilar Gomez and E. Nasi
On the Gating Mechanisms of the Light-dependent Conductance in Pecten Hyperpolarizing Photoreceptors: Does Light Remove Inactivation in Voltage-dependent K Channels?
J. Gen. Physiol., April 25, 2005; 125(5): 455 - 464.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Kojima, A. Terakita, T. Ishikawa, Y. Tsukahara, A. Maeda, and Y. Shichida
A Novel Go-mediated Phototransduction Cascade in Scallop Visual Cells
J. Biol. Chem., September 12, 1997; 272(37): 22979 - 22982.
[Abstract] [Full Text] [PDF]


-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2008 by Society for Neuroscience ONLINE ISSN: 1529-2401
-