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Journal of Neuroscience, Vol 15, 4196-4208, Copyright © 1995 by Society for Neuroscience
Cytochrome-oxidase blobs in cat primary visual cortex
KM Murphy, DG Jones and RC Van Sluyters
McMaster University, Department of Psychology, Hamilton, Ontario, Canada.
Cytochrome-oxidase blobs are central to two of the most influential ideas
in contemporary visual neuroscience--cortical modularity and parallel
processing pathways. In particular, the regular 2D array of
cytochrome-oxidase-rich blobs in primate visual cortex is arguably the most
compelling evidence for cortical modularity and has been hypothesized to
mark a separate processing stream through the visual cortex. Although
previously a variety of mammals have been studied, blobs have only been
demonstrated in the visual cortex of primates, which has led to the
conclusion that blobs represent a primate-specific feature of visual
cortical organization. Here we demonstrate the presence of
cytochrome-oxidase blobs in a nonprimate species. Throughout the full
tangential extent of layers II-III in cat visual cortex the
cytochrome-oxidase staining pattern is distinctly patchy, with the darkly
stained blobs forming a regular 2D array. In addition, the blobs in cat
visual cortex are functionally related to the underlying ocular dominance
columns. The presence of cytochrome-oxidase blobs in the cat clearly
demonstrates that they no longer can be considered a primate-specific
feature of visual cortical organization.
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