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Volume 17, Number 16,
Issue of August 15, 1997
pp. 6447-6462
Copyright ©1997 Society for Neuroscience
Anterior Forebrain Neurons Develop Selectivity by an Intermediate
Stage of Birdsong Learning
Received March 31, 1997; revised May 27, 1997; accepted May 30, 1997.
Michele M. Solis and
Allison J. Doupe
Keck Center for Integrative Neuroscience and Neuroscience Graduate
Program, Departments of Physiology and Psychiatry, University of
California, San Francisco, San Francisco, California 94143-0444
Auditory neurons of the anterior forebrain (AF) in adult zebra
finches are highly selective for the bird's own song (BOS): they
respond more to BOS than to songs of other zebra finches (conspecifics)
and to BOS played in reverse. In contrast, juvenile AF neurons are not
selective at 30 d of age, responding equally well to all song
stimuli. Both BOS and tutor song experience are required by juveniles
for normal song learning and may produce the selective properties of
adult neurons. Because such selectivity could subserve song learning,
it is important to determine when it arises. Birds were therefore
studied at an intermediate stage of learning, after substantial
experience of both tutor song and their own developing (plastic)
song.
Extracellular single neuron recordings in 60-d-old zebra finches
revealed that AF neurons had significant song and order selectivity for
both tutor song and BOS (the bird's plastic song). The degree of BOS
selectivity was less than that found in adults, as indicated in part by
60 d neurons that were sensitive to the local order within
syllables but not yet to the global order of syllables within a song.
When responses to BOS and tutor song were compared, most neurons
preferred BOS, some preferred tutor song, and others responded equally
to both stimuli. The latter type of neuron was not simply immature,
because many of these neurons responded significantly more to BOS and
tutor song than to conspecific and reverse songs.
The selectivity of AF neurons at 60 d is markedly different from
the unselective properties of neurons at 30 d and may function in
vocal learning at this stage. Moreover, the selectivity for both BOS
and tutor song raises the possibility that both aspects of the birds'
sensory experience during learning are reflected in properties of AF
neurons.
Key words:
auditory selectivity;
song selectivity;
order
selectivity;
temporal processing;
experience-dependent plasticity;
zebra finch;
song learning;
LMAN;
Area X
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