 |
||||
|
||||
|
||||
|
||||
Previous Article | Next Article
Volume 17, Number 22, Issue of November 15, 1997 pp. 8702-8710
The Murine P84 Neural Adhesion Molecule Is SHPS-1, a Member of the Phosphatase-Binding Protein Family
Received May 19, 1997; revised Aug. 22, 1997; accepted Aug. 29, 1997.
S. Comu1, W. Weng1, S. Olinsky1, P. Ishwad1, Z. Mi2, J. Hempel3, S. Watkins4, C. F. Lagenaur2, and V. Narayanan1, 2, 5 1 Department of Pediatrics,
The Children's Hospital of Pittsburgh, 2 Departments of Neurobiology, 3 Biological Sciences, 4 Cell Biology and Physiology, and 5 Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania P84 is a neuronal membrane glycoprotein that promotes the attachment and neurite outgrowth of cultured murine cerebellar cells. The heterophilic adhesive properties of P84 and its localization at sites of synaptogenesis suggest that it may be involved in regulation of synapse formation or maintenance. P84 is expressed in subsets of neurons throughout the CNS. By cloning the cDNA encoding murine P84, we have discovered that this molecule is a member of a family of phosphatase-binding proteins and is identical to the murine SHPS-1 cDNA. Here we report the cloning of two alternatively spliced forms of P84 and describe its localization within the CNS by in situ hybridization.
Key words: P84; neural adhesion molecule; neurite growth; protein tyrosine phosphatase; synaptogenesis; phosphatase binding protein; SHPS-1
This article has been cited by other articles:
M. L. Johansen and E. J. Brown
Dual Regulation of SIRP{alpha} Phosphorylation by Integrins and CD47
J. Biol. Chem., August 17, 2007; 282(33): 24219 - 24230.
[Abstract] [Full Text] [PDF]
C. S. Park, R. Gong, J. Stuart, and S.-J. Tang
Molecular Network and Chromosomal Clustering of Genes Involved in Synaptic Plasticity in the Hippocampus
J. Biol. Chem., October 6, 2006; 281(40): 30195 - 30211.
[Abstract] [Full Text] [PDF]
H. Ikeda, H. Okazawa, H. Ohnishi, Y. Murata, P.-A. Oldenborg, and T. Matozaki
Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.
J. Immunol., September 1, 2006; 177(5): 3123 - 3132.
[Abstract] [Full Text] [PDF]
X. X. Wang and K. H. Pfenninger
Functional analysis of SIRP{alpha} in the growth cone
J. Cell Sci., January 1, 2006; 119(1): 172 - 183.
[Abstract] [Full Text] [PDF]
M. Olsson, P. Bruhns, W. A. Frazier, J. V. Ravetch, and P.-A. Oldenborg
Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia
Blood, May 1, 2005; 105(9): 3577 - 3582.
[Abstract] [Full Text] [PDF]
H. Mitsuhashi, A. Yoshikawa, N. Sasagawa, Y. Hayashi, and S. Ishiura
Denervation Enhances the Expression of SHPS-1 in Rat Skeletal Muscle
J. Biochem., April 1, 2005; 137(4): 495 - 502.
[Abstract] [Full Text] [PDF]
L. Piccio, W. Vermi, K. S. Boles, A. Fuchs, C. A. Strader, F. Facchetti, M. Cella, and M. Colonna
Adhesion of human T cells to antigen-presenting cells through SIRP{beta}2-CD47 interaction costimulates T-cell proliferation
Blood, March 15, 2005; 105(6): 2421 - 2427.
[Abstract] [Full Text] [PDF]
H. Ohnishi, Y. Kaneko, H. Okazawa, M. Miyashita, R. Sato, A. Hayashi, K. Tada, S. Nagata, M. Takahashi, and T. Matozaki
Differential Localization of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Substrate-1 and CD47 and Its Molecular Mechanisms in Cultured Hippocampal Neurons
J. Neurosci., March 9, 2005; 25(10): 2702 - 2711.
[Abstract] [Full Text] [PDF]
H. Okazawa, S.-i. Motegi, N. Ohyama, H. Ohnishi, T. Tomizawa, Y. Kaneko, P.-A. Oldenborg, O. Ishikawa, and T. Matozaki
Negative Regulation of Phagocytosis in Macrophages by the CD47-SHPS-1 System
J. Immunol., February 15, 2005; 174(4): 2004 - 2011.
[Abstract] [Full Text] [PDF]
G. Brooke, J. D. Holbrook, M. H. Brown, and A. N. Barclay
Human Lymphocytes Interact Directly with CD47 through a Novel Member of the Signal Regulatory Protein (SIRP) Family
J. Immunol., August 15, 2004; 173(4): 2562 - 2570.
[Abstract] [Full Text] [PDF]
A. Hayashi, H. Ohnishi, H. Okazawa, S. Nakazawa, H. Ikeda, S.-i. Motegi, N. Aoki, S. Kimura, M. Mikuni, and T. Matozaki
Positive Regulation of Phagocytosis by SIRP{beta} and Its Signaling Mechanism in Macrophages
J. Biol. Chem., July 9, 2004; 279(28): 29450 - 29460.
[Abstract] [Full Text] [PDF]
H. Ohnishi, H. Kobayashi, H. Okazawa, Y. Ohe, K. Tomizawa, R. Sato, and T. Matozaki
Ectodomain Shedding of SHPS-1 and Its Role in Regulation of Cell Migration
J. Biol. Chem., July 2, 2004; 279(27): 27878 - 27887.
[Abstract] [Full Text] [PDF]
T. Ogura, T. Noguchi, R. Murai-Takebe, T. Hosooka, N. Honma, and M. Kasuga
Resistance of B16 Melanoma Cells to CD47-induced Negative Regulation of Motility as a Result of Aberrant N-Glycosylation of SHPS-1
J. Biol. Chem., April 2, 2004; 279(14): 13711 - 13720.
[Abstract] [Full Text] [PDF]
A. Fukunaga, H. Nagai, T. Noguchi, H. Okazawa, T. Matozaki, X. Yu, C. F. Lagenaur, N. Honma, M. Ichihashi, M. Kasuga, et al.
Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Substrate 1 Regulates the Migration of Langerhans Cells from the Epidermis to Draining Lymph Nodes
J. Immunol., April 1, 2004; 172(7): 4091 - 4099.
[Abstract] [Full Text] [PDF]
R. Murai-Takebe, T. Noguchi, T. Ogura, T. Mikami, K. Yanagi, K. Inagaki, H. Ohnishi, T. Matozaki, and M. Kasuga
Ubiquitination-mediated Regulation of Biosynthesis of the Adhesion Receptor SHPS-1 in Response to Endoplasmic Reticulum Stress
J. Biol. Chem., March 19, 2004; 279(12): 11616 - 11625.
[Abstract] [Full Text] [PDF]
T. T. Chen, E. J. Brown, E. J. Huang, and W. E. Seaman
Expression and Activation of Signal Regulatory Protein {alpha} on Astrocytomas
Cancer Res., January 1, 2004; 64(1): 117 - 127.
[Abstract] [Full Text] [PDF]
D.-H. Chung, M. B. Humphrey, M. C. Nakamura, D. G. Ginzinger, W. E. Seaman, and M. R. Daws
CMRF-35-Like Molecule-1, a Novel Mouse Myeloid Receptor, Can Inhibit Osteoclast Formation
J. Immunol., December 15, 2003; 171(12): 6541 - 6548.
[Abstract] [Full Text] [PDF]
T. Yamao, T. Noguchi, O. Takeuchi, U. Nishiyama, H. Morita, T. Hagiwara, H. Akahori, T. Kato, K. Inagaki, H. Okazawa, et al.
Negative Regulation of Platelet Clearance and of the Macrophage Phagocytic Response by the Transmembrane Glycoprotein SHPS-1
J. Biol. Chem., October 11, 2002; 277(42): 39833 - 39839.
[Abstract] [Full Text] [PDF]
M. Seiffert, P. Brossart, C. Cant, M. Cella, M. Colonna, W. Brugger, L. Kanz, A. Ullrich, and H.-J. Buhring
Signal-regulatory protein {alpha} (SIRP{alpha}) but not SIRP{beta} is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34+CD38{-} hematopoietic cells
Blood, May 1, 2001; 97(9): 2741 - 2749.
[Abstract] [Full Text] [PDF]
M. TICCHIONI, V. RAIMONDI, L. LAMY, J. WIJDENES, F. P. LINDBERG, E. J. BROWN, and A. BERNARD
Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow
FASEB J, February 1, 2001; 15(2): 341 - 350.
[Abstract] [Full Text] [PDF]
M. I. Kontaridis, X. Liu, L. Zhang, and A. M. Bennett
SHP-2 complex formation with the SHP-2 substrate-1 during C2C12 myogenesis
J. Cell Sci., January 6, 2001; 114(11): 2187 - 2198.
[Abstract] [Full Text] [PDF]
I. Babic, A. Schallhorn, F. P. Lindberg, and F. R. Jirik
SHPS-1 Induces Aggregation of Ba/F3 Pro-B Cells Via an Interaction with CD47
J. Immunol., April 1, 2000; 164(7): 3652 - 3658.
[Abstract] [Full Text] [PDF]
M. Seiffert, C. Cant, Z. Chen, I. Rappold, W. Brugger, L. Kanz, E. J. Brown, A. Ullrich, and H.-J. Buhring
Human Signal-Regulatory Protein Is Expressed on Normal, But Not on Subsets of Leukemic Myeloid Cells and Mediates Cellular Adhesion Involving Its Counterreceptor CD47
Blood, December 1, 1999; 94(11): 3633 - 3643.
[Abstract] [Full Text] [PDF]
P. Jiang, C. F. Lagenaur, and V. Narayanan
Integrin-associated Protein Is a Ligand for the P84 Neural Adhesion Molecule
J. Biol. Chem., January 8, 1999; 274(2): 559 - 562.
[Abstract] [Full Text] [PDF]
C. Saginario, H. Sterling, C. Beckers, R. Kobayashi, M. Solimena, E. Ullu, and A. Vignery
MFR, a Putative Receptor Mediating the Fusion of Macrophages
Mol. Cell. Biol., November 1, 1998; 18(11): 6213 - 6223.
[Abstract] [Full Text]
M. G. Myers Jr., R. Mendez, P. Shi, J. H. Pierce, R. Rhoads, and M. F. White
The COOH-terminal Tyrosine Phosphorylation Sites on IRS-1 Bind SHP-2 and Negatively Regulate Insulin Signaling
J. Biol. Chem., October 9, 1998; 273(41): 26908 - 26914.
[Abstract] [Full Text] [PDF]
A. Veillette, E. Thibaudeau, and S. Latour
High Expression of Inhibitory Receptor SHPS-1 and Its Association with Protein-tyrosine Phosphatase SHP-1 in Macrophages
J. Biol. Chem., August 28, 1998; 273(35): 22719 - 22728.
[Abstract] [Full Text] [PDF]
X. Han, H. Sterling, Y. Chen, C. Saginario, E. J. Brown, W. A. Frazier, F. P. Lindberg, and A. Vignery
CD47, a Ligand for the Macrophage Fusion Receptor, Participates in Macrophage Multinucleation
J. Biol. Chem., November 22, 2000; 275(48): 37984 - 37992.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|