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Previous Article | Next Article
Volume 17, Number 24, Issue of December 15, 1997 pp. 9642-9655
The Origin, Location, and Projections of the Embryonic Abdominal Motorneurons of Drosophila
Matthias Landgraf1, Torsten Bossing2, Gerd M. Technau3, and Michael Bate1 1 Department of Zoology, Cambridge University, Cambridge CB2 3EJ, United Kingdom, 2 Wellcome/CRC Institute, Cambridge CB2 1QR, United Kingdom, and 3 Institut für Genetik, Universität Mainz, 55122 Mainz, Germany
We have used a retrograde labeling technique to identify motorneurons for each of the 30 body wall muscles of an abdominal hemisegment in the late stage 16 Drosophila embryo. Each motorneuron has a characteristic cell body position, dendritic arborization, and axonal projection. In addition, we have determined the neuroblasts of origin for most of the motorneurons we describe. Some organizational principles for the neuromuscular system have become apparent: (1) There is no obvious topographic relationship between the cell body positions of motorneurons and the position or orientation of the muscles they innervate; (2) motorneurons that innervate muscles of similar position and orientation are often clustered and have overlapping dendritic trees; (3) morphologically similar motorneurons are generally derived from a common neuroblast and innervate operationally related muscles; and (4) neuroblasts can give rise to more than one morphological type of motorneuron.
Key words: Drosophila; motorneuron; development; lineage; structure; connectivity; arborization; neuroblast
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