WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience MBF Bioscience Neurolucida
 QUICK SEARCH:   [advanced]


     
-


HOME
  |  
SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (185)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hoffman, D. A.
Right arrow Articles by Johnston, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hoffman, D. A.
Right arrow Articles by Johnston, D.

 Previous Article  |  Next Article 

The Journal of Neuroscience, May 15, 1998, 18(10):3521-3528

Downregulation of Transient K+ Channels in Dendrites of Hippocampal CA1 Pyramidal Neurons by Activation of PKA and PKC

Dax A. Hoffman and Daniel Johnston

Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030

We have reported recently a high density of transient A-type K+ channels located in the distal dendrites of CA1 hippocampal pyramidal neurons and shown that these channels shape EPSPs, limit the back-propagation of action potentials, and prevent dendritic action potential initiation (). Because of the importance of these channels in dendritic signal propagation, their modulation by protein kinases would be of significant interest. We investigated the effects of activators of cAMP-dependent protein kinase (PKA) and the Ca2+-dependent phospholipid-sensitive protein kinase (PKC) on K+ channels in cell-attached patches from the distal dendrites of hippocampal CA1 pyramidal neurons. Inclusion of the membrane-permeant PKA activators 8-bromo-cAMP (8-br-cAMP) or forskolin in the dendritic patch pipette resulted in a depolarizing shift in the activation curve for the transient channels of ~15 mV. Activation of PKC by either of two phorbol esters also resulted in a 15 mV depolarizing shift of the activation curve. Neither PKA nor PKC activation affected the sustained or slowly inactivating component of the total outward current. This downregulation of transient K+ channels in the distal dendrites may be responsible for some of the frequently reported increases in cell excitability found after PKA and PKC activation. In support of this hypothesis, we found that activation of either PKA or PKC significantly increased the amplitude of back-propagating action potentials in distal dendrites.

Key words: potassium channels; IK(A); dendrite; protein kinase A; protein kinase C; hippocampus; phorbol esters; cAMP; action potential


Copyright © 1998 Society for Neuroscience  0270-6474/98/18103521-08$05.00/0


This article has been cited by other articles:


Home page
Physiol. Rev.Home page
P. J. Sjostrom, E. A. Rancz, A. Roth, and M. Hausser
Dendritic Excitability and Synaptic Plasticity
Physiol Rev, April 1, 2008; 88(2): 769 - 840.
[Abstract] [Full Text] [PDF]


Home page
Mol. Pharmacol.Home page
J.-H. Lee, B.-H. Lee, S.-H. Choi, I.-S. Yoon, M. K. Pyo, T.-J. Shin, W.-S. Choi, Y. Lim, H. Rhim, K. H. Won, et al.
Ginsenoside Rg3 Inhibits Human Kv1.4 Channel Currents by Interacting with the Lys531 Residue
Mol. Pharmacol., March 1, 2008; 73(3): 619 - 626.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
T. J. Bell, K. Y. Miyashiro, J.-Y. Sul, R. McCullough, P. T. Buckley, J. Jochems, D. F. Meaney, P. Haydon, C. Cantor, T. D. Parsons, et al.
From the Cover: Cytoplasmic BKCa channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons
PNAS, February 12, 2008; 105(6): 1901 - 1906.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. W. Shiflett, R. P. Martini, J. C. Mauna, R. L. Foster, E. Peet, and E. Thiels
Cue-Elicited Reward-Seeking Requires Extracellular Signal-Regulated Kinase Activation in the Nucleus Accumbens
J. Neurosci., February 6, 2008; 28(6): 1434 - 1443.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
K. B. Walsh and J. Zhang
Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C
Am J Physiol Heart Circ Physiol, February 1, 2008; 294(2): H1010 - H1017.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
X. W. Fu, C. Nurse, and E. Cutz
Characterization of slowly inactivating KV{alpha} current in rabbit pulmonary neuroepithelial bodies: effects of hypoxia and nicotine
Am J Physiol Lung Cell Mol Physiol, October 1, 2007; 293(4): L892 - L902.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
L. D. Ellis, R. Krahe, C. W. Bourque, R. J. Dunn, and M. J. Chacron
Muscarinic Receptors Control Frequency Tuning Through the Downregulation of an A-Type Potassium Current
J Neurophysiol, September 1, 2007; 98(3): 1526 - 1537.
[Abstract] [Full Text] [PDF]


Home page
J. Pharmacol. Exp. Ther.Home page
Z.-G. Zhao, M. Zhang, X.-M. Zeng, X.-W. Fei, L.-Y. Liu, Z.-H. Zhang, and Y.-A. Mei
Flufenamic Acid Bi-Directionally Modulates the Transient Outward K+ Current in Rat Cerebellar Granule Cells
J. Pharmacol. Exp. Ther., July 1, 2007; 322(1): 195 - 204.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
D. Fernandez de Sevilla, M. Fuenzalida, A. B. Porto Pazos, and W. Buno
Selective Shunting of the NMDA EPSP Component by the Slow Afterhyperpolarization in Rat CA1 Pyramidal Neurons
J Neurophysiol, May 1, 2007; 97(5): 3242 - 3255.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
A. Ruiz-Gomez, B. Mellstrom, D. Tornero, E. Morato, M. Savignac, H. Holguin, K. Aurrekoetxea, P. Gonzalez, C. Gonzalez-Garcia, V. Cena, et al.
G Protein-coupled Receptor Kinase 2-mediated Phosphorylation of Downstream Regulatory Element Antagonist Modulator Regulates Membrane Trafficking of Kv4.2 Potassium Channel
J. Biol. Chem., January 12, 2007; 282(2): 1205 - 1215.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
X. Chen, L.-L. Yuan, C. Zhao, S. G. Birnbaum, A. Frick, W. E. Jung, T. L. Schwarz, J. D. Sweatt, and D. Johnston
Deletion of Kv4.2 Gene Eliminates Dendritic A-Type K+ Current and Enhances Induction of Long-Term Potentiation in Hippocampal CA1 Pyramidal Neurons.
J. Neurosci., November 22, 2006; 26(47): 12143 - 12151.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
L. Bai, X. Huang, Q. Yang, and J.-Y. Wu
Spatiotemporal Patterns of an Evoked Network Oscillation in Neocortical Slices: Coupled Local Oscillators
J Neurophysiol, November 1, 2006; 96(5): 2528 - 2538.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
B. Lancaster, H. Hu, B. Gibb, and J. F. Storm
Kinetics of ion channel modulation by cAMP in rat hippocampal neurones
J. Physiol., October 15, 2006; 576(2): 403 - 417.
[Abstract] [Full Text] [PDF]


Home page
J. Pharmacol. Exp. Ther.Home page
H. S. Ahn, S. E. Kim, H.-J. Jang, M.-J. Kim, D.-J. Rhie, S.-H. Yoon, Y.-H. Jo, M.-S. Kim, K.-W. Sung, and S. J. Hahn
Interaction of Riluzole with the Closed Inactivated State of Kv4.3 Channels
J. Pharmacol. Exp. Ther., October 1, 2006; 319(1): 323 - 331.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
C. M. Santi, G. Ferreira, B. Yang, V.-R. Gazula, A. Butler, A. Wei, L. K. Kaczmarek, and L. Salkoff
Opposite regulation of Slick and Slack K+ channels by neuromodulators.
J. Neurosci., May 10, 2006; 26(19): 5059 - 5068.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
L. A. Schrader, S. G. Birnbaum, B. M. Nadin, Y. Ren, D. Bui, A. E. Anderson, and J. D. Sweatt
ERK/MAPK regulates the Kv4.2 potassium channel by direct phosphorylation of the pore-forming subunit
Am J Physiol Cell Physiol, March 1, 2006; 290(3): C852 - C861.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
S. Gasparini and J. C. Magee
State-Dependent Dendritic Computation in Hippocampal CA1 Pyramidal Neurons
J. Neurosci., February 15, 2006; 26(7): 2088 - 2100.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
L.-L. Yuan, X. Chen, K. Kunjilwar, P. Pfaffinger, and D. Johnston
Acceleration of K+ channel inactivation by MEK inhibitor U0126
Am J Physiol Cell Physiol, January 1, 2006; 290(1): C165 - C171.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
J. Kim, D.-S. Wei, and D. A. Hoffman
Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neurones
J. Physiol., November 15, 2005; 569(1): 41 - 57.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
Y. M. Leung, I. Ahmed, L. Sheu, R. G. Tsushima, N. E. Diamant, M. Hara, and H. Y. Gaisano
Electrophysiological Characterization of Pancreatic Islet Cells in the Mouse Insulin Promoter-Green Fluorescent Protein Mouse
Endocrinology, November 1, 2005; 146(11): 4766 - 4775.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
J. A. Wolf, J. T. Moyer, M. T. Lazarewicz, D. Contreras, M. Benoit-Marand, P. O'Donnell, and L. H. Finkel
NMDA/AMPA Ratio Impacts State Transitions and Entrainment to Oscillations in a Computational Model of the Nucleus Accumbens Medium Spiny Projection Neuron
J. Neurosci., October 5, 2005; 25(40): 9080 - 9095.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
W. Yuan, A. Burkhalter, and J. M. Nerbonne
Functional Role of the Fast Transient Outward K+ Current IA in Pyramidal Neurons in (Rat) Primary Visual Cortex
J. Neurosci., October 5, 2005; 25(40): 9185 - 9194.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
B. L. Shay, M. Sawchuk, D. W. Machacek, and S. Hochman
Serotonin 5-HT2 Receptors Induce a Long-Lasting Facilitation of Spinal Reflexes Independent of Ionotropic Receptor Activity
J Neurophysiol, October 1, 2005; 94(4): 2867 - 2877.
[Abstract] [Full Text] [PDF]


Home page
J. Pharmacol. Exp. Ther.Home page
F. J. Nasif, K. Sidiropoulou, X.-T. Hu, and F. J. White
Repeated Cocaine Administration Increases Membrane Excitability of Pyramidal Neurons in the Rat Medial Prefrontal Cortex
J. Pharmacol. Exp. Ther., March 1, 2005; 312(3): 1305 - 1313.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
M. Gallego, R. Setien, L. Puebla, M. d. C. Boyano-Adanez, E. Arilla, and O. Casis
{alpha}1-Adrenoceptors stimulate a G{alpha}s protein and reduce the transient outward K+ current via a cAMP/PKA-mediated pathway in the rat heart
Am J Physiol Cell Physiol, March 1, 2005; 288(3): C577 - C585.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
S. Gasparini, M. Migliore, and J. C. Magee
On the Initiation and Propagation of Dendritic Spikes in CA1 Pyramidal Neurons
J. Neurosci., December 8, 2004; 24(49): 11046 - 11056.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
N. A. Otmakhova and J. E. Lisman
Contribution of Ih and GABAB to Synaptically Induced Afterhyperpolarizations in CA1: A Brake on the NMDA Response
J Neurophysiol, October 1, 2004; 92(4): 2027 - 2039.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
K. J. Rhodes, K. I. Carroll, M. A. Sung, L. C. Doliveira, M. M. Monaghan, S. L. Burke, B. W. Strassle, L. Buchwalder, M. Menegola, J. Cao, et al.
KChIPs and Kv4 {alpha} Subunits as Integral Components of A-Type Potassium Channels in Mammalian Brain
J. Neurosci., September 8, 2004; 24(36): 7903 - 7915.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
X. Chen and D. Johnston
Properties of single voltage-dependent K+ channels in dendrites of CA1 pyramidal neurones of rat hippocampus
J. Physiol., August 15, 2004; 559(1): 187 - 203.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
C. Bernard, A. Anderson, A. Becker, N. P. Poolos, H. Beck, and D. Johnston
Acquired Dendritic Channelopathy in Temporal Lobe Epilepsy
Science, July 23, 2004; 305(5683): 532 - 535.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
R. H. Cudmore and G. G. Turrigiano
Long-Term Potentiation of Intrinsic Excitability in LV Visual Cortical Neurons
J Neurophysiol, July 1, 2004; 92(1): 341 - 348.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
S. G. Birnbaum, A. W. Varga, L.-L. Yuan, A. E. Anderson, J. D. Sweatt, and L. A. Schrader
Structure and Function of Kv4-Family Transient Potassium Channels
Physiol Rev, July 1, 2004; 84(3): 803 - 833.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
E. A. Kramar, B. Lin, C.-Y. Lin, A. C. Arai, C. M. Gall, and G. Lynch
A Novel Mechanism for the Facilitation of Theta-Induced Long-Term Potentiation by Brain-Derived Neurotrophic Factor
J. Neurosci., June 2, 2004; 24(22): 5151 - 5161.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
A. W. Varga, L.-L. Yuan, A. E. Anderson, L. A. Schrader, G.-Y. Wu, J. R. Gatchel, D. Johnston, and J. D. Sweatt
Calcium-Calmodulin-Dependent Kinase II Modulates Kv4.2 Channel Expression and Upregulates Neuronal A-Type Potassium Currents
J. Neurosci., April 7, 2004; 24(14): 3643 - 3654.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
C. E. Young and C. R. Yang
Dopamine D1/D5 Receptor Modulates State-Dependent Switching of Soma-Dendritic Ca2+ Potentials via Differential Protein Kinase A and C Activation in Rat Prefrontal Cortical Neurons
J. Neurosci., January 7, 2004; 24(1): 8 - 23.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
W. Wong and L. C. Schlichter
Differential Recruitment of Kv1.4 and Kv4.2 to Lipid Rafts by PSD-95
J. Biol. Chem., January 2, 2004; 279(1): 444 - 452.
[Abstract] [Full Text] [PDF]


Home page
Learn. Mem.Home page
G. Daoudal and D. Debanne
Long-Term Plasticity of Intrinsic Excitability: Learning Rules and Mechanisms
Learn. Mem., November 1, 2003; 10(6): 456 - 465.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
C. Bernard and D. Johnston
Distance-Dependent Modifiable Threshold for Action Potential Back-Propagation in Hippocampal Dendrites
J Neurophysiol, September 1, 2003; 90(3): 1807 - 1816.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
H.-J. Hu, K. S. Glauner, and R. W. Gereau IV
ERK Integrates PKA and PKC Signaling in Superficial Dorsal Horn Neurons. I. Modulation of A-Type K+ Currents
J Neurophysiol, September 1, 2003; 90(3): 1671 - 1679.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
H.-J. Hu and R. W. Gereau IV
ERK Integrates PKA and PKC Signaling in Superficial Dorsal Horn Neurons. II. Modulation of Neuronal Excitability
J Neurophysiol, September 1, 2003; 90(3): 1680 - 1688.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. Martina, G. L. Yao, and B. P. Bean
Properties and Functional Role of Voltage-Dependent Potassium Channels in Dendrites of Rat Cerebellar Purkinje Neurons
J. Neurosci., July 2, 2003; 23(13): 5698 - 5707.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
J. M. Christie and G. L. Westbrook
Regulation of Backpropagating Action Potentials in Mitral Cell Lateral Dendrites by A-Type Potassium Currents
J Neurophysiol, May 1, 2003; 89(5): 2466 - 2472.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
A. Frick, J. Magee, H. J. Koester, M. Migliore, and D. Johnston
Normalization of Ca2+ Signals by Small Oblique Dendrites of CA1 Pyramidal Neurons
J. Neurosci., April 15, 2003; 23(8): 3243 - 3250.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
A. Czarnecki, L. Dufy-Barbe, S. Huet, M.-F. Odessa, and L. Bresson-Bepoldin
Potassium channel expression level is dependent on the proliferation state in the GH3 pituitary cell line
Am J Physiol Cell Physiol, April 1, 2003; 284(4): C1054 - C1064.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
C.-C. Lien and P. Jonas
Kv3 Potassium Conductance is Necessary and Kinetically Optimized for High-Frequency Action Potential Generation in Hippocampal Interneurons
J. Neurosci., March 15, 2003; 23(6): 2058 - 2068.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
J. Mitterdorfer and B. P. Bean
Potassium Currents during the Action Potential of Hippocampal CA3 Neurons
J. Neurosci., December 1, 2002; 22(23): 10106 - 10115.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
L. A. Schrader, A. E. Anderson, A. Mayne, P. J. Pfaffinger, and J. D. Sweatt
PKA Modulation of Kv4.2-Encoded A-Type Potassium Channels Requires Formation of a Supramolecular Complex
J. Neurosci., December 1, 2002; 22(23): 10123 - 10133.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
Y. Xu, N. Chiamvimonvat, A. E. Vazquez, S. Akunuru, N. Ratner, and E. N. Yamoah
Gene-Targeted Deletion of Neurofibromin Enhances the Expression of a Transient Outward K+ Current in Schwann Cells: A Protein Kinase A-Mediated Mechanism
J. Neurosci., November 1, 2002; 22(21): 9194 - 9202.
[Abstract] [Full Text] [PDF]


Home page
Mol. Endocrinol.Home page
R. A. DeFazio and S. M. Moenter
Estradiol Feedback Alters Potassium Currents and Firing Properties of Gonadotropin-Releasing Hormone Neurons
Mol. Endocrinol., October 1, 2002; 16(10): 2255 - 2265.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
D. B. Carr, D. C. Cooper, S. L. Ulrich, N. Spruston, and D. J. Surmeier
Serotonin Receptor Activation Inhibits Sodium Current and Dendritic Excitability in Prefrontal Cortex via a Protein Kinase C-Dependent Mechanism
J. Neurosci., August 15, 2002; 22(16): 6846 - 6855.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
G. M. J. Ramakers and J. F. Storm
A postsynaptic transient K+ current modulated by arachidonic acid regulates synaptic integration and threshold for LTP induction in hippocampal pyramidal cells
PNAS, July 23, 2002; 99(15): 10144 - 10149.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
K. Berglund, M. Midorikawa, and M. Tachibana
Increase in the Pool Size of Releasable Synaptic Vesicles by the Activation of Protein Kinase C in Goldfish Retinal Bipolar Cells
J. Neurosci., June 15, 2002; 22(12): 4776 - 4785.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
L.-L. Yuan, J. P. Adams, M. Swank, J. D. Sweatt, and D. Johnston
Protein Kinase Modulation of Dendritic K+ Channels in Hippocampus Involves a Mitogen-Activated Protein Kinase Pathway
J. Neurosci., June 15, 2002; 22(12): 4860 - 4868.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
S. Watanabe, D. A. Hoffman, M. Migliore, and D. Johnston
Dendritic K+ channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons
PNAS, June 11, 2002; 99(12): 8366 - 8371.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
C. Chen, J. C. Magee, and N. G. Bazan
Cyclooxygenase-2 Regulates Prostaglandin E2 Signaling in Hippocampal Long-Term Synaptic Plasticity
J Neurophysiol, June 1, 2002; 87(6): 2851 - 2857.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
W. Wong, E. W. Newell, D. G. M. Jugloff, O. T. Jones, and L. C. Schlichter
Cell Surface Targeting and Clustering Interactions between Heterologously Expressed PSD-95 and the Shal Voltage-gated Potassium Channel, Kv4.2
J. Biol. Chem., May 31, 2002; 277(23): 20423 - 20430.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
N. L. Golding, W. L. Kath, and N. Spruston
Dichotomy of Action-Potential Backpropagation in CA1 Pyramidal Neuron Dendrites
J Neurophysiol, December 1, 2001; 86(6): 2998 - 3010.
[Abstract] [Full Text] [PDF]


Home page
Learn. Mem.Home page
H. T. Blair, G. E. Schafe, E. P. Bauer, S. M. Rodrigues, and J. E. LeDoux
Synaptic Plasticity in the Lateral Amygdala: A Cellular Hypothesis of Fear Conditioning
Learn. Mem., September 1, 2001; 8(5): 229 - 242.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
A. Ivanov and G. Aston-Jones
Local Opiate Withdrawal in Locus Coeruleus Neurons In Vitro
J Neurophysiol,