 |
|||||
|
|||||
|
|||||
|
|||||
|
|||||
Previous Article | Next Article
The Journal of Neuroscience, July 15, 1999, 19(14):5782-5791
-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins
Natalie Ostrerova1, Leonard Petrucelli1, Matthew Farrer2, Nitinkumar Mehta2, Peter Choi1, John Hardy2, and Benjamin Wolozin1 1 Department of Pharmacology, Loyola University Medical Center, Maywood, Illinois 60153, and 2 Department of Pharmacology, Mayo Clinic, Jacksonville, Florida 32224
-Synuclein has been implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Mutations in
Key words: 14-3-3 proteins; Alzheimer's disease; apoptosis; BAD; extracellular regulated kinase; Parkinson's disease; protein kinase C; synuclein
Copyright © 1999 Society for Neuroscience 0270-6474/99/19145782-10$05.00/0
This article has been cited by other articles:
E. A. Cartier, L. A. Parra, T. B. Baust, M. Quiroz, G. Salazar, V. Faundez, L. Egana, and G. E. Torres
A Biochemical and Functional Protein Complex Involving Dopamine Synthesis and Transport into Synaptic Vesicles
J. Biol. Chem., January 15, 2010; 285(3): 1957 - 1966.
[Abstract] [Full Text] [PDF]
J. Wang, H. Lou, C. J. Pedersen, A. D. Smith, and R. G. Perez
14-3-3{zeta} Contributes to Tyrosine Hydroxylase Activity in MN9D Cells: LOCALIZATION OF DOPAMINE REGULATORY PROTEINS TO MITOCHONDRIA
J. Biol. Chem., May 22, 2009; 284(21): 14011 - 14019.
[Abstract] [Full Text] [PDF]
M. Bisaglia, S. Mammi, and L. Bubacco
Structural insights on physiological functions and pathological effects of {alpha}-synuclein
FASEB J, February 1, 2009; 23(2): 329 - 340.
[Abstract] [Full Text] [PDF]
M. A. McFarland, C. E. Ellis, S. P. Markey, and R. L. Nussbaum
Proteomics Analysis Identifies Phosphorylation-dependent {alpha}-Synuclein Protein Interactions
Mol. Cell. Proteomics, November 1, 2008; 7(11): 2123 - 2137.
[Abstract] [Full Text] [PDF]
K. E. Paleologou, A. W. Schmid, C. C. Rospigliosi, H.-Y. Kim, G. R. Lamberto, R. A. Fredenburg, P. T. Lansbury Jr., C. O. Fernandez, D. Eliezer, M. Zweckstetter, et al.
Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of {alpha}-Synuclein
J. Biol. Chem., June 13, 2008; 283(24): 16895 - 16905.
[Abstract] [Full Text] [PDF]
M. Ahmad, S. Attoub, M. N. Singh, F. L. Martin, and O. M. A. El-Agnaf
{gamma}-Synuclein and the progression of cancer
FASEB J, November 1, 2007; 21(13): 3419 - 3430.
[Abstract] [Full Text] [PDF]
T. J. Nelson and D. L. Alkon
Protection against beta-Amyloid-induced Apoptosis by Peptides Interacting with beta-Amyloid
J. Biol. Chem., October 26, 2007; 282(43): 31238 - 31249.
[Abstract] [Full Text] [PDF]
C. C. Stichel, X.-R. Zhu, V. Bader, B. Linnartz, S. Schmidt, and H. Lubbert
Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage
Hum. Mol. Genet., October 15, 2007; 16(20): 2377 - 2393.
[Abstract] [Full Text] [PDF]
V. Limviphuvadh, S. Tanaka, S. Goto, K. Ueda, and M. Kanehisa
The commonality of protein interaction networks determined in neurodegenerative disorders (NDDs)
Bioinformatics, August 15, 2007; 23(16): 2129 - 2138.
[Abstract] [Full Text] [PDF]
D. Zhang, A. Kanthasamy, Y. Yang, V. Anantharam, and A. Kanthasamy
Protein Kinase C{delta} Negatively Regulates Tyrosine Hydroxylase Activity and Dopamine Synthesis by Enhancing Protein Phosphatase-2A Activity in Dopaminergic Neurons
J. Neurosci., May 16, 2007; 27(20): 5349 - 5362.
[Abstract] [Full Text] [PDF]
M. Periquet, T. Fulga, L. Myllykangas, M. G. Schlossmacher, and M. B. Feany
Aggregated {alpha}-Synuclein Mediates Dopaminergic Neurotoxicity In Vivo
J. Neurosci., March 21, 2007; 27(12): 3338 - 3346.
[Abstract] [Full Text] [PDF]
M. Fujita, S. Sugama, M. Nakai, T. Takenouchi, J. Wei, T. Urano, S. Inoue, and M. Hashimoto
{alpha}-Synuclein Stimulates Differentiation of Osteosarcoma Cells: RELEVANCE TO DOWN-REGULATION OF PROTEASOME ACTIVITY
J. Biol. Chem., February 23, 2007; 282(8): 5736 - 5748.
[Abstract] [Full Text] [PDF]
J. R. Mazzulli, A. J. Mishizen, B. I. Giasson, D. R. Lynch, S. A. Thomas, A. Nakashima, T. Nagatsu, A. Ota, and H. Ischiropoulos
Cytosolic Catechols Inhibit {alpha}-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates
J. Neurosci., September 27, 2006; 26(39): 10068 - 10078.
[Abstract] [Full Text] [PDF]
Y. Leng and D.-M. Chuang
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.
J. Neurosci., July 12, 2006; 26(28): 7502 - 7512.
[Abstract] [Full Text] [PDF]
E. M. Chalovich, J.-h. Zhu, J. Caltagarone, R. Bowser, and C. T. Chu
Functional Repression of cAMP Response Element in 6-Hydroxydopamine-treated Neuronal Cells
J. Biol. Chem., June 30, 2006; 281(26): 17870 - 17881.
[Abstract] [Full Text] [PDF]
E. Avraham, R. Szargel, A. Eyal, R. Rott, and S. Engelender
Glycogen Synthase Kinase 3beta Modulates Synphilin-1 Ubiquitylation and Cellular Inclusion Formation by SIAH: IMPLICATIONS FOR PROTEASOMAL FUNCTION AND LEWY BODY FORMATION
J. Biol. Chem., December 30, 2005; 280(52): 42877 - 42886.
[Abstract] [Full Text] [PDF]
R. Ved, S. Saha, B. Westlund, C. Perier, L. Burnam, A. Sluder, M. Hoener, C. M. P. Rodrigues, A. Alfonso, C. Steer, et al.
Similar Patterns of Mitochondrial Vulnerability and Rescue Induced by Genetic Modification of {alpha}-Synuclein, Parkin, and DJ-1 in Caenorhabditis elegans
J. Biol. Chem., December 30, 2005; 280(52): 42655 - 42668.
[Abstract] [Full Text] [PDF]
W. W. Smith, H. Jiang, Z. Pei, Y. Tanaka, H. Morita, A. Sawa, V. L. Dawson, T. M. Dawson, and C. A. Ross
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity
Hum. Mol. Genet., December 15, 2005; 14(24): 3801 - 3811.
[Abstract] [Full Text] [PDF]
K. Goyal, L. J. Walton, J. A. Browne, A. M. Burnell, and A. Tunnacliffe
Molecular Anhydrobiology: Identifying Molecules Implicated in Invertebrate Anhydrobiosis
Integr. Comp. Biol., November 1, 2005; 45(5): 702 - 709.
[Abstract] [Full Text] [PDF]
D. Bridges and G. B. G. Moorhead
14-3-3 Proteins: A Number of Functions for a Numbered Protein
Sci. Signal., August 9, 2005; 2005(296): re10 - re10.
[Abstract] [Full Text] [PDF]
X. M. Peng, R. Tehranian, P. Dietrich, L. Stefanis, and R. G. Perez
{alpha}-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells
J. Cell Sci., August 1, 2005; 118(15): 3523 - 3530.
[Abstract] [Full Text] [PDF]
Y. Shin, J. Klucken, C. Patterson, B. T. Hyman, and P. J. McLean
The Co-chaperone Carboxyl Terminus of Hsp70-interacting Protein (CHIP) Mediates {alpha}-Synuclein Degradation Decisions between Proteasomal and Lysosomal Pathways
J. Biol. Chem., June 24, 2005; 280(25): 23727 - 23734.
[Abstract] [Full Text] [PDF]
C. R. Jimenez, F. J. Stam, K. W. Li, Y. Gouwenberg, M. P. Hornshaw, F. De Winter, J. Verhaagen, and A. B. Smit
Proteomics of the Injured Rat Sciatic Nerve Reveals Protein Expression Dynamics During Regeneration
Mol. Cell. Proteomics, February 1, 2005; 4(2): 120 - 132.
[Abstract] [Full Text] [PDF]
H. J. Rideout, P. Dietrich, Q. Wang, W. T. Dauer, and L. Stefanis
{alpha}-Synuclein Is Required for the Fibrillar Nature of Ubiquitinated Inclusions Induced by Proteasomal Inhibition in Primary Neurons
J. Biol. Chem., November 5, 2004; 279(45): 46915 - 46920.
[Abstract] [Full Text] [PDF]
S. Chandra, F. Fornai, H.-B. Kwon, U. Yazdani, D. Atasoy, X. Liu, R. E. Hammer, G. Battaglia, D. C. German, P. E. Castillo, et al.
Double-knockout mice for {alpha}- and {beta}-synucleins: Effect on synaptic functions
PNAS, October 12, 2004; 101(41): 14966 - 14971.
[Abstract] [Full Text] [PDF]
Y. Zhou, G. Gu, D. R. Goodlett, T. Zhang, C. Pan, T. J. Montine, K. S. Montine, R. H. Aebersold, and J. Zhang
Analysis of {alpha}-Synuclein-associated Proteins by Quantitative Proteomics
J. Biol. Chem., September 10, 2004; 279(37): 39155 - 39164.
[Abstract] [Full Text] [PDF]
J.-i. Satoh, T. Yamamura, and K. Arima
The 14-3-3 Protein {epsilon} Isoform Expressed in Reactive Astrocytes in Demyelinating Lesions of Multiple Sclerosis Binds to Vimentin and Glial Fibrillary Acidic Protein in Cultured Human Astrocytes
Am. J. Pathol., August 1, 2004; 165(2): 577 - 592.
[Abstract] [Full Text] [PDF]
M. Hashimoto, P. Bar-on, G. Ho, T. Takenouchi, E. Rockenstein, L. Crews, and E. Masliah
{beta}-Synuclein Regulates Akt Activity in Neuronal Cells: A POSSIBLE MECHANISM FOR NEUROPROTECTION IN PARKINSON'S DISEASE
J. Biol. Chem., May 28, 2004; 279(22): 23622 - 23629.
[Abstract] [Full Text] [PDF]
C. A. Wilson, D. D. Murphy, B. I. Giasson, B. Zhang, J. Q. Trojanowski, and V. M.-Y. Lee
Degradative organelles containing mislocalized {alpha}- and {beta}-synuclein proliferate in presenilin-1 null neurons
J. Cell Biol., May 10, 2004; 165(3): 335 - 346.
[Abstract] [Full Text] [PDF]
M. K. Dougherty and D. K. Morrison
Unlocking the code of 14-3-3
J. Cell Sci., April 15, 2004; 117(10): 1875 - 1884.
[Abstract] [Full Text] [PDF]
A. RECCHIA, P. DEBETTO, A. NEGRO, D. GUIDOLIN, S. D. SKAPER, and P. GIUSTI
{alpha}-Synuclein and Parkinson's disease
FASEB J, April 1, 2004; 18(6): 617 - 626.
[Abstract] [Full Text] [PDF]
A. SIDHU, C. WERSINGER, and P. VERNIER
Does {alpha}-synuclein modulate dopaminergic synaptic content and tone at the synapse?
FASEB J, April 1, 2004; 18(6): 637 - 647.
[Abstract] [Full Text] [PDF]
N. Ninkina, K. Papachroni, D. C. Robertson, O. Schmidt, L. Delaney, F. O'Neill, F. Court, A. Rosenthal, S. M. Fleetwood-Walker, A. M. Davies, et al.
Neurons Expressing the Highest Levels of {gamma}-Synuclein Are Unaffected by Targeted Inactivation of the Gene
Mol. Cell. Biol., November 15, 2003; 23(22): 8233 - 8245.
[Abstract] [Full Text] [PDF]
A. Iwata, M. Maruyama, T. Akagi, T. Hashikawa, I. Kanazawa, S. Tsuji, and N. Nukina
Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies
Hum. Mol. Genet., October 16, 2003; 12(20): 2625 - 2635.
[Abstract] [Full Text] [PDF]
J. Martinez, I. Moeller, H. Erdjument-Bromage, P. Tempst, and B. Lauring
Parkinson's Disease-associated alpha -Synuclein Is a Calmodulin Substrate
J. Biol. Chem., May 2, 2003; 278(19): 17379 - 17387.
[Abstract] [Full Text] [PDF]
H. Snyder, K. Mensah, C. Theisler, J. Lee, A. Matouschek, and B. Wolozin
Aggregated and Monomeric alpha -Synuclein Bind to the S6' Proteasomal Protein and Inhibit Proteasomal Function
J. Biol. Chem., March 28, 2003; 278(14): 11753 - 11759.
[Abstract] [Full Text] [PDF]
D. Kirik, L. E. Annett, C. Burger, N. Muzyczka, R. J. Mandel, and A. Bjorklund
Nigrostriatal alpha -synucleinopathy induced by viral vector-mediated overexpression of human alpha -synuclein: A new primate model of Parkinson's disease
PNAS, March 4, 2003; 100(5): 2884 - 2889.
[Abstract] [Full Text] [PDF]
F. Dou, W. J. Netzer, K. Tanemura, F. Li, F. U. Hartl, A. Takashima, G. K. Gouras, P. Greengard, and H. Xu
Chaperones increase association of tau protein with microtubules
PNAS, January 21, 2003; 100(2): 721 - 726.
[Abstract] [Full Text] [PDF]
O. CHIBA-FALEK and R.L. NUSSBAUM
Regulation of {alpha}-Synuclein Expression: Implications for Parkinson's Disease
Cold Spring Harb Symp Quant Biol, January 1, 2003; 68(0): 409 - 416.
[Abstract] [PDF]
N. Gosavi, H.-J. Lee, J. S. Lee, S. Patel, and S.-J. Lee
Golgi Fragmentation Occurs in the Cells with Prefibrillar alpha -Synuclein Aggregates and Precedes the Formation of Fibrillar Inclusion
J. Biol. Chem., December 6, 2002; 277(50): 48984 - 48992.
[Abstract] [Full Text] [PDF]
J.-H. Zhu, S. M. Kulich, T. D. Oury, and C. T. Chu
Cytoplasmic Aggregates of Phosphorylated Extracellular Signal-Regulated Protein Kinases in Lewy Body Diseases
Am. J. Pathol., December 1, 2002; 161(6): 2087 - 2098.
[Abstract] [Full Text] [PDF]
J. Lotharius and P. Brundin
Impaired dopamine storage resulting from {alpha}-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
Hum. Mol. Genet., October 1, 2002; 11(20): 2395 - 2407.
[Abstract] [Full Text] [PDF]
S. M. Park, H. Y. Jung, H. O. Kim, H. Rhim, S. R. Paik, K. C. Chung, J. H. Park, and J. Kim
Evidence that alpha -synuclein functions as a negative regulator of Ca++-dependent alpha -granule release from human platelets
Blood, September 18, 2002; 100(7): 2506 - 2514.
[Abstract] [Full Text] [PDF]
Z.-Z. Pan, W. Bruening, B. I. Giasson, V. M.-Y. Lee, and A. K. Godwin
gamma -Synuclein Promotes Cancer Cell Survival and Inhibits Stress- and Chemotherapy Drug-induced Apoptosis by Modulating MAPK Pathways
J. Biol. Chem., September 13, 2002; 277(38): 35050 - 35060.
[Abstract] [Full Text] [PDF]
Y.-H. Suh and F. Checler
Amyloid Precursor Protein, Presenilins, and alpha -Synuclein: Molecular Pathogenesis and Pharmacological Applications in Alzheimer's Disease
Pharmacol. Rev., September 1, 2002; 54(3): 469 - 525.
[Abstract] [Full Text] [PDF]
S. M. Park, H. Y. Jung, T. D. Kim, J. H. Park, C.-H. Yang, and J. Kim
Distinct Roles of the N-terminal-binding Domain and the C-terminal-solubilizing Domain of alpha -Synuclein, a Molecular Chaperone
J. Biol. Chem., August 2, 2002; 277(32): 28512 - 28520.
[Abstract] [Full Text] [PDF]
R. G. Perez, J. C. Waymire, E. Lin, J. J. Liu, F. Guo, and M. J. Zigmond
A Role for alpha -Synuclein in the Regulation of Dopamine Biosynthesis
J. Neurosci., April 15, 2002; 22(8): 3090 - 3099.
[Abstract] [Full Text] [PDF]
D. Kirik, C. Rosenblad, C. Burger, C. Lundberg, T. E. Johansen, N. Muzyczka, R. J. Mandel, and A. Bjorklund
Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of alpha -Synuclein in the Nigrostriatal System
J. Neurosci., April 1, 2002; 22(7): 2780 - 2791.
[Abstract] [Full Text] [PDF]
B.-H. Ahn, H. Rhim, S. Y. Kim, Y.-M. Sung, M.-Y. Lee, J.-Y. Choi, B. Wolozin, J.-S. Chang, Y. H. Lee, T. K. Kwon, et al.
alpha -Synuclein Interacts with Phospholipase D Isozymes and Inhibits Pervanadate-induced Phospholipase D Activation in Human Embryonic Kidney-293 Cells
J. Biol. Chem., March 29, 2002; 277(14): 12334 - 12342.
[Abstract] [Full Text] [PDF]
N. B. Cole, D. D. Murphy, T. Grider, S. Rueter, D. Brasaemle, and R. L. Nussbaum
Lipid Droplet Binding and Oligomerization Properties of the Parkinson's Disease Protein alpha -Synuclein
J. Biol. Chem., February 15, 2002; 277(8): 6344 - 6352.
[Abstract] [Full Text] [PDF]
B. Wolozin and N. Golts
Book Review: Iron and Parkinson's Disease
Neuroscientist, February 1, 2002; 8(1): 22 - 32.
[Abstract] [PDF]
L. Stefanis, K. E. Larsen, H. J. Rideout, D. Sulzer, and L. A. Greene
Expression of A53T Mutant But Not Wild-Type alpha -Synuclein in PC12 Cells Induces Alterations of the Ubiquitin-Dependent Degradation System, Loss of Dopamine Release, and Autophagic Cell Death
J. Neurosci., December 15, 2001; 21(24): 9549 - 9560.
[Abstract] [Full Text] [PDF]
D J Burn and E Jaros
Multiple system atrophy: cellular and molecular pathology
Mol. Pathol., December 1, 2001; 54(6): 419 - 426.
[Abstract] [Full Text] [PDF]
R. Bussell Jr. and D. Eliezer
Residual Structure and Dynamics in Parkinson's Disease-associated Mutants of alpha -Synuclein
J. Biol. Chem., November 30, 2001; 276(49): 45996 - 46003.
[Abstract] [Full Text] [PDF]
S. Waelter, A. Boeddrich, R. Lurz, E. Scherzinger, G. Lueder, H. Lehrach, and E. E. Wanker
Accumulation of Mutant Huntingtin Fragments in Aggresome-like Inclusion Bodies as a Result of Insufficient Protein Degradation
Mol. Biol. Cell, May 1, 2001; 12(5): 1393 - 1407.
[Abstract] [Full Text]
Y. Tanaka, S. Engelender, S. Igarashi, R. K. Rao, T. Wanner, R. E. Tanzi, A. Sawa, V. L. Dawson, T. M. Dawson, and C. A. Ross
Inducible expression of mutant {{alpha}}-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
Hum. Mol. Genet., April 1, 2001; 10(9): 919 - 926.
[Abstract] [Full Text] [PDF]
F. J. S. LEE, F. LIU, Z. B. PRISTUPA, and H. B. NIZNIK
Direct binding and functional coupling of {alpha}-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
FASEB J, April 1, 2001; 15(6): 916 - 926.
[Abstract] [Full Text] [PDF]
S. J. Tabrizi, M. Orth, J. M. Wilkinson, J.-W. Taanman, T. T. Warner, J. M. Cooper, and A. H.V. Schapira
Expression of mutant {alpha}-synuclein causes increased susceptibility to dopamine toxicity
Hum. Mol. Genet., November 1, 2000; 9(18): 2683 - 2689.
[Abstract] [Full Text] [PDF]
P. J. Kahle, M. Neumann, L. Ozmen, V. Muller, H. Jacobsen, A. Schindzielorz, M. Okochi, U. Leimer, H. van der Putten, A. Probst, et al.
Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant alpha -Synuclein in Human and Transgenic Mouse Brain
J. Neurosci., September 1, 2000; 20(17): 6365 - 6373.
[Abstract] [Full Text] [PDF]
N. Ostrerova-Golts, L. Petrucelli, J. Hardy, J. M. Lee, M. Farer, and B. Wolozin
The A53T alpha -Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity
J. Neurosci., August 15, 2000; 20(16): 6048 - 6054.
[Abstract] [Full Text] [PDF]
L. J. Hsu, Y. Sagara, A. Arroyo, E. Rockenstein, A. Sisk, M. Mallory, J. Wong, T. Takenouchi, M. Hashimoto, and E. Masliah
{alpha}-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress
Am. J. Pathol., August 1, 2000; 157(2): 401 - 410.
[Abstract] [Full Text] [PDF]
B. Wolozin and C. Behl
Mechanisms of Neurodegenerative Disorders: Part 1: Protein Aggregates
Arch Neurol, June 1, 2000; 57(6): 793 - 796.
[Full Text] [PDF]
C. A. da Costa, K. Ancolio, and F. Checler
Wild-type but Not Parkinson's Disease-related Ala-53 right-arrow Thr Mutant alpha -Synuclein Protects Neuronal Cells from Apoptotic Stimuli
J. Biol. Chem., July 28, 2000; 275(31): 24065 - 24069.
[Abstract] [Full Text] [PDF]
A. N. Pronin, A. J. Morris, A. Surguchov, and J. L. Benovic
Synucleins Are a Novel Class of Substrates for G Protein-coupled Receptor Kinases
J. Biol. Chem., August 18, 2000; 275(34): 26515 - 26522.
[Abstract] [Full Text] [PDF]
M. Hashiguchi, K. Sobue, and H. K. Paudel
14-3-3zeta Is an Effector of Tau Protein Phosphorylation
J. Biol. Chem., August 11, 2000; 275(33): 25247 - 25254.
[Abstract] [Full Text] [PDF]
E. M. Jeanclos, L. Lin, M. W. Treuil, J. Rao, M. A. DeCoster, and R. Anand
The Chaperone Protein 14-3-3eta Interacts with the Nicotinic Acetylcholine Receptor alpha 4 Subunit. EVIDENCE FOR A DYNAMIC ROLE IN SUBUNIT STABILIZATION
J. Biol. Chem., July 20, 2001; 276(30): 28281 - 28290.
[Abstract] [Full Text] [PDF]
M. S. Nielsen, H. Vorum, E. Lindersson, and P. H. Jensen
Ca2+ Binding to alpha -Synuclein Regulates Ligand Binding and Oligomerization
J. Biol. Chem., June 15, 2001; 276(25): 22680 - 22684.
[Abstract] [Full Text] [PDF]
A. Iwata, M. Maruyama, I. Kanazawa, and N. Nukina
alpha -Synuclein Affects the MAPK Pathway and Accelerates Cell Death
J. Biol. Chem., November 21, 2001; 276(48): 45320 - 45329.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|