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Previous Article | Next Article
The Journal of Neuroscience, August 15, 1999, 19(16):7162-7174
Motion Opponency in Visual Cortex
David J. Heeger1, Geoffrey M. Boynton1, Jonathan B. Demb1, Eyal Seidemann2, and William T. Newsome2 1 Department of Psychology, and 2 Howard Hughes Medical Institute and Department of Neurobiology, Stanford University, Stanford, California 94305-2130
Perceptual studies suggest that visual motion perception is mediated by opponent mechanisms that correspond to mutually suppressive populations of neurons sensitive to motions in opposite directions. We tested for a neuronal correlate of motion opponency using functional magnetic resonance imaging (fMRI) to measure brain activity in human visual cortex. There was strong motion opponency in a secondary visual cortical area known as the human MT complex (MT+), but there was little evidence of motion opponency in primary visual cortex. To determine whether the level of opponency in human and monkey are comparable, a variant of these experiments was performed using multiunit electrophysiological recording in areas MT and MST of the macaque monkey brain. Although there was substantial variability in the degree of opponency between recording sites, the monkey and human data were qualitatively similar on average. These results provide further evidence that: (1) direction-selective signals underly human MT+ responses, (2) neuronal signals in human MT+ support visual motion perception, (3) human MT+ is homologous to macaque monkey MT and adjacent motion sensitive brain areas, and (4) that fMRI measurements are correlated with average spiking activity.
Key words: MT; V1; neuroimaging; fMRI; motion; visual motion perception; motion opponency; vision; visual cortex
Copyright © 1999 Society for Neuroscience 0270-6474/99/19167162-13$05.00/0
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