 |
 Previous Article | Next Article 
Journal of Neuroscience, Vol 2, 361-375, Copyright © 1982 by Society for Neuroscience
Neuronal firing in the inferotemporal cortex of the monkey in a visual memory task
JM Fuster and JP Jervey
The objective of this study was to elucidate the functional role of neurons
in the inferotemporal cortex of the primate. Single unit activity was
recorded with microelectrodes in monkeys performing a visual delayed
matching-to-sample task. On each trial, the animal was exposed briefly to a
color - the sample - and, after a period of delay, had to select the same
color among two or four colors simultaneously presented. Thus, correct
performance of the task required perception, retention, and recognition of
the sample color for every trial. A large number of inferotemporal units
were seen to react to the stimuli with changes of firing frequency. Many
units showed color-dependent reactions, suggesting their involvement in
perception and discrimination of colors. A substantial contingent of cells
showed increased, sustained, and in some cases, color-dependent discharge
during the delay which was not necessarily preceded or succeeded by firing
changes in sample or match periods. It is proposed that those cells were
engaged in temporary retention of the sample stimulus. Since most of the
inferotemporal units examined showed firing changes in more than one period
of a trial, they appeared to be involved in more than one of the operations
required by the task. Thus, the data do not support a clear-cut topographic
separation of visual functions within the inferotmeporal cortex. However,
neurons that appear to participate in visual memory, either exclusively or
in addition to other functions, are concentrated in the cortex of the lower
banks of the superior temporal sulcus.
This article has been cited by other articles:
|
|
|
|
 
F. Mormann, S. Kornblith, R. Q. Quiroga, A. Kraskov, M. Cerf, I. Fried, and C. Koch
Latency and Selectivity of Single Neurons Indicate Hierarchical Processing in the Human Medial Temporal Lobe
J. Neurosci.,
September 3, 2008;
28(36):
8865 - 8872.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
X. Peng, M. E. Sereno, A. K. Silva, S. R. Lehky, and A. B. Sereno
Shape Selectivity in Primate Frontal Eye Field
J Neurophysiol,
August 1, 2008;
100(2):
796 - 814.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Rissman, A. Gazzaley, and M. D'Esposito
Dynamic Adjustments in Prefrontal, Hippocampal, and Inferior Temporal Interactions with Increasing Visual Working Memory Load
Cereb Cortex,
July 1, 2008;
18(7):
1618 - 1629.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. A. Ojemann, J. Schoenfield-McNeill, and D. Corina
The Roles of Human Lateral Temporal Cortical Neuronal Activity in Recent Verbal Memory Encoding
Cereb Cortex,
May 9, 2008;
(2008)
bhn071v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. K. Sreenivasan, J. Katz, and A. P. Jha
Temporal Characteristics of Top-Down Modulations during Working Memory Maintenance: An Event-related Potential Study of the N170 Component.
J. Cogn. Neurosci.,
November 1, 2007;
19(11):
1836 - 1844.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Inoue and A. Mikami
Top-Down Signal of Retrieved Information From Prefrontal to Inferior Temporal Cortices
J Neurophysiol,
October 1, 2007;
98(4):
1965 - 1974.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y.-D. Zhou, A. Ardestani, and J. M. Fuster
Distributed and Associative Working Memory
Cereb Cortex,
September 1, 2007;
17(suppl_1):
i77 - i87.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. J. Dubin and C. J. Duffy
Behavioral Influences on Cortical Neuronal Responses to Optic Flow
Cereb Cortex,
July 1, 2007;
17(7):
1722 - 1732.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. J. Hulme and S Zeki
The Sightless View: Neural Correlates of Occluded Objects
Cereb Cortex,
May 1, 2007;
17(5):
1197 - 1205.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. R. Conway and D. Y. Tsao
Color Architecture in Alert Macaque Cortex Revealed by fMRI
Cereb Cortex,
November 1, 2006;
16(11):
1604 - 1613.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
X. Li, B. Kim, and M. A. Basso
Transient Pauses in Delay-Period Activity of Superior Colliculus Neurons
J Neurophysiol,
April 1, 2006;
95(4):
2252 - 2264.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Inoue and A. Mikami
Prefrontal Activity During Serial Probe Reproduction Task: Encoding, Mnemonic, and Retrieval Processes
J Neurophysiol,
February 1, 2006;
95(2):
1008 - 1041.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. D. Runyan and P. K. Dash
Distinct prefrontal molecular mechanisms for information storage lasting seconds versus minutes
Learn. Mem.,
May 1, 2005;
12(3):
232 - 238.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Sobotka, M. D. Diltz, and J. L. Ringo
Can Delay-Period Activity Explain Working Memory?
J Neurophysiol,
January 1, 2005;
93(1):
128 - 136.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. E. Latham and S. Nirenberg
Computing and Stability in Cortical Networks
Neural Comput.,
July 1, 2004;
16(7):
1385 - 1412.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Tallon-Baudry, S. Mandon, W. A. Freiwald, and A. K. Kreiter
Oscillatory Synchrony in the Monkey Temporal Lobe Correlates with Performance in a Visual Short-term Memory Task
Cereb Cortex,
July 1, 2004;
14(7):
713 - 720.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Ranganath, M. X. Cohen, C. Dam, and M. D'Esposito
Inferior Temporal, Prefrontal, and Hippocampal Contributions to Visual Working Memory Maintenance and Associative Memory Retrieval
J. Neurosci.,
April 21, 2004;
24(16):
3917 - 3925.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Reutimann, V. Yakovlev, S. Fusi, and W. Senn
Climbing Neuronal Activity as an Event-Based Cortical Representation of Time
J. Neurosci.,
March 31, 2004;
24(13):
3295 - 3303.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. W. Bisley, D. Zaksas, J. A. Droll, and T. Pasternak
Activity of Neurons in Cortical Area MT During a Memory for Motion Task
J Neurophysiol,
January 1, 2004;
91(1):
286 - 300.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
G. N. Elston
Cortex, Cognition and the Cell: New Insights into the Pyramidal Neuron and Prefrontal Function
Cereb Cortex,
November 1, 2003;
13(11):
1124 - 1138.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. J. Druzgal and M. D'Esposito
Dissecting Contributions of Prefrontal Cortex and Fusiform Face Area to Face Working Memory
J. Cogn. Neurosci.,
August 1, 2003;
15(6):
771 - 784.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K.-I. Tsutsui, M. Jiang, H. Sakata, and M. Taira
Short-Term Memory and Perceptual Decision for Three-Dimensional Visual Features in the Caudal Intraparietal Sulcus (Area CIP)
J. Neurosci.,
July 2, 2003;
23(13):
5486 - 5495.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. M. Umeno and M. E. Goldberg
Spatial Processing in the Monkey Frontal Eye Field. II. Memory Responses
J Neurophysiol,
November 1, 2001;
86(5):
2344 - 2352.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. A. Erickson and R. Desimone
Responses of Macaque Perirhinal Neurons during and after Visual Stimulus Association Learning
J. Neurosci.,
December 1, 1999;
19(23):
10404 - 10416.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. A. Ojemann and J. Schoenfield-McNeill
Activity of Neurons in Human Temporal Cortex during Identification and Memory for Names and Words
J. Neurosci.,
July 1, 1999;
19(13):
5674 - 5682.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Quintana and J. M. Fuster
From Perception to Action: Temporal Integrative Functions of Prefrontal and Parietal Neurons
Cereb Cortex,
April 1, 1999;
9(3):
213 - 221.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Colombo, T. Fernandez, K. Nakamura, and C. G. Gross
Functional Differentiation Along the Anterior-Posterior Axis of the Hippocampus in Monkeys
J Neurophysiol,
August 1, 1998;
80(2):
1002 - 1005.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Hasegawa, T. Sawaguchi, and K. Kubota
Monkey Prefrontal Neuronal Activity Coding the Forthcoming Saccade in an Oculomotor Delayed Matching-to-Sample Task
J Neurophysiol,
January 1, 1998;
79(1):
322 - 333.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Bodner, Y.-D. Zhou, and J. M. Fuster
Binary Mapping of Cortical Spike Trains in Short-Term Memory
J Neurophysiol,
April 1, 1997;
77(4):
2219 - 2222.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O Jensen, M A Idiart, and J E Lisman
Physiologically realistic formation of autoassociative memory in networks with theta/gamma oscillations: role of fast NMDA channels.
Learn. Mem.,
January 1, 1996;
3(2-3):
243 - 256.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. H. R. Maunsell
The Brain's Visual World: Representation of Visual Targets in Cerebral Cortex
Science,
November 3, 1995;
270(5237):
764 - 769.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. Lisman and M. Idiart
Storage of 7 +/- 2 short-term memories in oscillatory subcycles
Science,
March 10, 1995;
267(5203):
1512 - 1515.
[Abstract]
[PDF]
|
|
|
|
|
|
|
K Sakai, Y Naya, and Y Miyashita
Neuronal tuning and associative mechanisms in form representation.
Learn. Mem.,
January 1, 1994;
1(2):
83 - 105.
[Abstract]
[PDF]
|
|
|
|
|
|
|
K Tanaka
Neuronal mechanisms of object recognition
Science,
October 29, 1993;
262(5134):
685 - 688.
[Abstract]
[PDF]
|
|
|
|
|
|
|
E. Miller, L Li, and R Desimone
A neural mechanism for working and recognition memory in inferior temporal cortex
Science,
November 29, 1991;
254(5036):
1377 - 1379.
[Abstract]
[PDF]
|
|
|
|
|
|
|
C.L. Colby
The Neuroanatomy and Neurophysiology of Attention
J Child Neurol,
January 1, 1991;
6(1_suppl):
S90 - S118.
[Abstract]
[PDF]
|
|
|
|
|
|
|
S. Wise and R Desimone
Behavioral neurophysiology: insights into seeing and grasping
Science,
November 4, 1988;
242(4879):
736 - 741.
[Abstract]
[PDF]
|
|
|
|
