 |
|||||
|
|||||
|
|||||
|
|||||
|
|||||
Previous Article | Next Article
The Journal of Neuroscience, March 1, 2000, 20(5):1964-1974
Interspike Intervals, Receptive Fields, and Information Encoding in Primary Visual Cortex
Daniel S. Reich1, 2, Ferenc Mechler2, Keith P. Purpura2, and Jonathan D. Victor2 1 Laboratory of Biophysics, The Rockefeller University, New York, New York 10021, and 2 Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021
In the primate primary visual cortex (V1), the significance of individual action potentials has been difficult to determine, particularly in light of the considerable trial-to-trial variability of responses to visual stimuli. We show here that the information conveyed by an action potential depends on the duration of the immediately preceding interspike interval (ISI). The interspike intervals can be grouped into several different classes on the basis of reproducible features in the interspike interval histograms. Spikes in different classes bear different relationships to the visual stimulus, both qualitatively (in terms of the average stimulus preceding each spike) and quantitatively (in terms of the amount of information encoded per spike and per second). Spikes preceded by very short intervals (3 msec or less) convey information most efficiently and contribute disproportionately to the overall receptive-field properties of the neuron. Overall, V1 neurons can transmit between 5 and 30 bits of information per second in response to rapidly varying, pseudorandom stimuli, with an efficiency of ~25%. Although some (but not all) of our results would be expected from neurons that use a firing-rate code to transmit information, the evidence suggests that visual neurons are well equipped to decode stimulus-related information on the basis of relative spike timing and ISI duration.
Key words: spike train; primary visual cortex; V1; information theory; white noise; receptive field; synaptic depression; synaptic facilitation; temporal coding; m-sequence; interspike interval
Copyright © 2000 Society for Neuroscience 0270-6474/00/2051964-11$05.00/0
This article has been cited by other articles:
P. Sabourin and G. S. Pollack
Behaviorally Relevant Burst Coding in Primary Sensory Neurons
J Neurophysiol, August 1, 2009; 102(2): 1086 - 1091.
[Abstract] [Full Text] [PDF]
C. R. Stoelzel, Y. Bereshpolova, A. G. Gusev, and H. A. Swadlow
The Impact of an LGNd Impulse on the Awake Visual Cortex: Synaptic Dynamics and the Sustained/Transient Distinction
J. Neurosci., May 7, 2008; 28(19): 5018 - 5028.
[Abstract] [Full Text] [PDF]
R. D. Kumbhani, M. J. Nolt, and L. A. Palmer
Precision, Reliability, and Information-Theoretic Analysis of Visual Thalamocortical Neurons
J Neurophysiol, November 1, 2007; 98(5): 2647 - 2663.
[Abstract] [Full Text] [PDF]
C. A. Atencio, D. T. Blake, F. Strata, S. W. Cheung, M. M. Merzenich, and C. E. Schreiner
Frequency-Modulation Encoding in the Primary Auditory Cortex of the Awake Owl Monkey
J Neurophysiol, October 1, 2007; 98(4): 2182 - 2195.
[Abstract] [Full Text] [PDF]
D. L. Rathbun, H. J. Alitto, T. G. Weyand, and W. M. Usrey
Interspike Interval Analysis of Retinal Ganglion Cell Receptive Fields
J Neurophysiol, August 1, 2007; 98(2): 911 - 919.
[Abstract] [Full Text] [PDF]
A.-M. M. Oswald, B. Doiron, and L. Maler
Interval Coding. I. Burst Interspike Intervals as Indicators of Stimulus Intensity
J Neurophysiol, April 1, 2007; 97(4): 2731 - 2743.
[Abstract] [Full Text] [PDF]
Z. Chi, W. Wu, Z. Haga, N. G. Hatsopoulos, and D. Margoliash
Template-Based Spike Pattern Identification With Linear Convolution and Dynamic Time Warping
J Neurophysiol, February 1, 2007; 97(2): 1221 - 1235.
[Abstract] [Full Text] [PDF]
B. N. Lundstrom and A. L. Fairhall
Decoding stimulus variance from a distributional neural code of interspike intervals.
J. Neurosci., August 30, 2006; 26(35): 9030 - 9037.
[Abstract] [Full Text] [PDF]
R. C. Froemke, I. A. Tsay, M. Raad, J. D. Long, and Y. Dan
Contribution of Individual Spikes in Burst-Induced Long-Term Synaptic Modification
J Neurophysiol, March 1, 2006; 95(3): 1620 - 1629.
[Abstract] [Full Text] [PDF]
B. S. Gutkin, G. B. Ermentrout, and A. D. Reyes
Phase-Response Curves Give the Responses of Neurons to Transient Inputs
J Neurophysiol, August 1, 2005; 94(2): 1623 - 1635.
[Abstract] [Full Text] [PDF]
C. L. Passaglia and J. B. Troy
Information Transmission Rates of Cat Retinal Ganglion Cells
J Neurophysiol, March 1, 2004; 91(3): 1217 - 1229.
[Abstract] [Full Text] [PDF]
T. Lu and X. Wang
Information Content of Auditory Cortical Responses to Time-Varying Acoustic Stimuli
J Neurophysiol, January 1, 2004; 91(1): 301 - 313.
[Abstract] [Full Text]
M. A. Escabi, L. M. Miller, H. L. Read, and C. E. Schreiner
Naturalistic Auditory Contrast Improves Spectrotemporal Coding in the Cat Inferior Colliculus
J. Neurosci., December 17, 2003; 23(37): 11489 - 11504.
[Abstract] [Full Text] [PDF]
E. Schneidman, W. Bialek, and M. J. Berry II
Synergy, Redundancy, and Independence in Population Codes
J. Neurosci., December 17, 2003; 23(37): 11539 - 11553.
[Abstract] [Full Text] [PDF]
A. Nabatiyan, J.F.A. Poulet, G. G. de Polavieja, and B. Hedwig
Temporal Pattern Recognition Based on Instantaneous Spike Rate Coding in a Simple Auditory System
J Neurophysiol, October 1, 2003; 90(4): 2484 - 2493.
[Abstract] [Full Text] [PDF]
J. M. Samonds, J. D. Allison, H. A. Brown, and A. B. Bonds
Cooperation between Area 17 Neuron Pairs Enhances Fine Discrimination of Orientation
J. Neurosci., March 15, 2003; 23(6): 2416 - 2425.
[Abstract] [Full Text] [PDF]
H. A. Swadlow, A. G. Gusev, and T. Bezdudnaya
Activation of a Cortical Column by a Thalamocortical Impulse
J. Neurosci., September 1, 2002; 22(17): 7766 - 7773.
[Abstract] [Full Text] [PDF]
F. Mechler, D. S. Reich, and J. D. Victor
Detection and Discrimination of Relative Spatial Phase by V1 Neurons
J. Neurosci., July 15, 2002; 22(14): 6129 - 6157.
[Abstract] [Full Text] [PDF]
M. A. Escabi and C. E. Schreiner
Nonlinear Spectrotemporal Sound Analysis by Neurons in the Auditory Midbrain
J. Neurosci., May 15, 2002; 22(10): 4114 - 4131.
[Abstract] [Full Text] [PDF]
D. S. Reich, F. Mechler, and J. D. Victor
Independent and Redundant Information in Nearby Cortical Neurons
Science, December 21, 2001; 294(5551): 2566 - 2568.
[Abstract] [Full Text] [PDF]
R. C. Liu, S. Tzonev, S. Rebrik, and K. D. Miller
Variability and Information in a Neural Code of the Cat Lateral Geniculate Nucleus
J Neurophysiol, December 1, 2001; 86(6): 2789 - 2806.
[Abstract] [Full Text] [PDF]
L. M. Miller, M. A. Escabi, and C. E. Schreiner
Feature Selectivity and Interneuronal Cooperation in the Thalamocortical System
J. Neurosci., October 15, 2001; 21(20): 8136 - 8144.
[Abstract] [Full Text] [PDF]
R. L. Jenison, J. W. H. Schnupp, R. A. Reale, and J. F. Brugge
Auditory Space-Time Receptive Field Dynamics Revealed by Spherical White-Noise Analysis
J. Neurosci., June 15, 2001; 21(12): 4408 - 4415.
[Abstract] [Full Text] [PDF]
D. S. Reich, F. Mechler, and J. D. Victor
Temporal Coding of Contrast in Primary Visual Cortex: When, What, and Why
J Neurophysiol, March 1, 2001; 85(3): 1039 - 1050.
[Abstract] [Full Text] [PDF]
D. S. Reich, F. Mechler, and J. D. Victor
Formal and Attribute-Specific Information in Primary Visual Cortex
J Neurophysiol, January 1, 2001; 85(1): 305 - 318.
[Abstract] [Full Text] [PDF]
P. Reinagel and R. C. Reid
Temporal Coding of Visual Information in the Thalamus
J. Neurosci., July 15, 2000; 20(14): 5392 - 5400.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|