QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (29) Citing Articles via Google Scholar Google Scholar Articles by Bosking, W. H. Articles by Fitzpatrick, D. Search for Related Content PubMed PubMed Citation Articles by Bosking, W. H. Articles by Fitzpatrick, D.

 Previous Article  |  Next Article 

The Journal of Neuroscience, March 15, 2000, 20(6):2346-2359

Functional Specificity of Callosal Connections in Tree Shrew Striate Cortex

William H. Bosking¹, Robert Kretz², Michele L. Pucak¹, and David Fitzpatrick¹

¹ Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, and ² Department of Anatomy, University of Fribourg, CH-1700 Fribourg, Switzerland

Although callosal connections have been shown to link extensive regions of primary visual cortex, the distribution of these connections with respect to the map of visual space and the map of orientation preference remains unclear. Here we combine optical imaging of intrinsic signals with injection of fluorescent microspheres to assess the functional specificity of callosal connections in the tree shrew. By imaging both hemispheres simultaneously while presenting a series of spatially restricted stimuli, we find that a substantial region of visual space is represented bilaterally. Each hemisphere includes a representation of the ipsilateral visual field that is highly compressed relative to that of the contralateral visual field and is most extensive in the lower visual field, where ~30^o of central visual space are represented bilaterally. Callosal connections extend throughout the region of bilateral representation but terminate in a spatially restricted manner that links visuotopically corresponding sites in the two hemispheres. In contrast, callosal connections appear to terminate without regard for the map of orientation preference, showing little sign of the orientation-specific modular and axial specificity that is characteristic of long-range horizontal connections. By coordinating the activity in the two hemispheres in a way that preserves nearest neighbor relationships, callosal connections may best be viewed as elements of local circuits that operate within a single bilateral representation of visual space.

Key words: optical imaging; intrinsic signals; corpus callosum; horizontal connections; visual field; visual cortex; orientation selectivity; visuotopic; ipsilateral visual field

---

Copyright © 2000 Society for Neuroscience  0270-6474/00/2062346-14$05.00/0

This article has been cited by other articles:

				N. L. Rochefort, P. Buzas, N. Quenech'du, A. Koza, U. T. Eysel, C. Milleret, and Z. F. Kisvarday Functional Selectivity of Interhemispheric Connections in Cat Visual Cortex Cereb Cortex, October 1, 2009; 19(10): 2451 - 2465. [Abstract] [Full Text] [PDF]

				J. Jeffs, J. M. Ichida, F. Federer, and A. Angelucci Anatomical Evidence for Classical and Extra-classical Receptive Field Completion Across the Discontinuous Horizontal Meridian Representation of Primate Area V2 Cereb Cortex, April 1, 2009; 19(4): 963 - 981. [Abstract] [Full Text] [PDF]

				R. Accolla, B. Bathellier, C. C. H. Petersen, and A. Carleton Differential Spatial Representation of Taste Modalities in the Rat Gustatory Cortex J. Neurosci., February 7, 2007; 27(6): 1396 - 1404. [Abstract] [Full Text] [PDF]

				S. D. Van Hooser, J. A. Heimel, S. Chung, and S. B. Nelson Lack of patchy horizontal connectivity in primary visual cortex of a mammal without orientation maps. J. Neurosci., July 19, 2006; 26(29): 7680 - 7692. [Abstract] [Full Text] [PDF]

				X. Xu, W. H. Bosking, L. E. White, D. Fitzpatrick, and V. A. Casagrande Functional Organization of Visual Cortex in the Prosimian Bush Baby Revealed by Optical Imaging of Intrinsic Signals J Neurophysiol, October 1, 2005; 94(4): 2748 - 2762. [Abstract] [Full Text] [PDF]

				X. Xu, W. Bosking, G. Sary, J. Stefansic, D. Shima, and V. Casagrande Functional Organization of Visual Cortex in the Owl Monkey J. Neurosci., July 14, 2004; 24(28): 6237 - 6247. [Abstract] [Full Text] [PDF]

				X. Xu, C. E. Collins, P. M. Kaskan, I. Khaytin, J. H. Kaas, and V. A. Casagrande Optical imaging of visually evoked responses in prosimian primates reveals conserved features of the middle temporal visual area PNAS, February 24, 2004; 101(8): 2566 - 2571. [Abstract] [Full Text] [PDF]

				H. J. Chisum, F. Mooser, and D. Fitzpatrick Emergent Properties of Layer 2/3 Neurons Reflect the Collinear Arrangement of Horizontal Connections in Tree Shrew Visual Cortex J. Neurosci., April 1, 2003; 23(7): 2947 - 2960. [Abstract] [Full Text] [PDF]

				D. C. Lyon, X. Xu, V. A. Casagrande, J. D. Stefansic, D. Shima, and J. H. Kaas Inaugural Article: Optical imaging reveals retinotopic organization of dorsal V3 in New World owl monkeys PNAS, November 26, 2002; 99(24): 15735 - 15742. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help