QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (54) Citing Articles via Google Scholar Google Scholar Articles by Ohara, S. Articles by Shibasaki, H. Search for Related Content PubMed PubMed Citation Articles by Ohara, S. Articles by Shibasaki, H.

 Previous Article  |  Next Article 

The Journal of Neuroscience, December 1, 2001, 21(23):9377-9386

Increased Synchronization of Cortical Oscillatory Activities between Human Supplementary Motor and Primary Sensorimotor Areas during Voluntary Movements

Shinji Ohara¹, Tatsuya Mima¹, Koichi Baba⁴, Akio Ikeda², Takeharu Kunieda³, Riki Matsumoto¹, Junichi Yamamoto¹, Masao Matsuhashi¹, Takashi Nagamine¹, Kenichi Hirasawa⁵, Tomokatsu Hori⁵, Tadahiro Mihara⁴, Nobuo Hashimoto³, Stephan Salenius⁶, and Hiroshi Shibasaki^{1, 2}

¹ Human Brain Research Center and Departments of ² Neurology and ³ Neurosurgery, Kyoto University Graduate School of Medicine, Shogoin, Sakyo, Kyoto, 606-8507, Japan, ⁴ The National Epilepsy Center, Shizuoka Higashi Hospital, Urushiyama, Shizuoka, 420-8688, Japan, ⁵ Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, Kawada-Cho, Shinjuku-Ku, Tokyo 162-8666, Japan, and ⁶ Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, FIN-02015HUT, Espoo, Finland

In human, both primary and nonprimary motor areas are involved in the control of voluntary movements. However, the dynamics of functional coupling among different motor areas has not been fully clarified yet. Because it has been proposed that the functional coupling among cortical areas might be achieved by the synchronization of oscillatory activity, we investigated the electrocorticographic coherence between the supplementary motor and primary sensorimotor areas (SMA and S1-M1) by means of event-related partial coherence analysis in 11 intractable epilepsy patients. We found premovement increase of coherence between the SMA proper and S1-M1 at the frequency of 0-33 Hz and between the pre-SMA and S1-M1 at 0-18 Hz. Coherence between the SMA proper and M1 started to increase 0.9 sec before the movement onset and peaked 0.3 sec after the movement. There was no systematic difference within the SMA (SMA proper vs pre-SMA) or within the S1-M1, in terms of the time course as well as the peak value of coherence. The phase spectra revealed near-zero phase difference in 57% (20 of 35) of region pairs analyzed, and the remaining pairs showed inconsistent results. This increase of synchronization between multiple motor areas in the preparation and execution of voluntary movements may reflect the multiregional functional interactions in human motor behavior.

Key words: event-related coherence; primary sensorimotor area; supplementary motor area; electrocorticography; voluntary movements; functional coupling

---

Copyright © 2001 Society for Neuroscience  0270-6474/01/21239377-10$05.00/0

This article has been cited by other articles:

				F. Darvas, K. J. Miller, R. P. N. Rao, and J. G. Ojemann Nonlinear Phase-Phase Cross-Frequency Coupling Mediates Communication between Distant Sites in Human Neocortex J. Neurosci., January 14, 2009; 29(2): 426 - 435. [Abstract] [Full Text] [PDF]

				J. D. Greenspan, S. Ohara, P. Franaszczuk, D. S. Veldhuijzen, and F. A. Lenz Cold Stimuli Evoke Potentials That Can Be Recorded Directly From Parasylvian Cortex in Humans J Neurophysiol, October 1, 2008; 100(4): 2282 - 2286. [Abstract] [Full Text] [PDF]

				T. Takei and K. Seki Spinomuscular Coherence in Monkeys Performing a Precision Grip Task J Neurophysiol, April 1, 2008; 99(4): 2012 - 2020. [Abstract] [Full Text] [PDF]

				R. Matsumoto, D. R. Nair, E. LaPresto, W. Bingaman, H. Shibasaki, and H. O. Luders Functional connectivity in human cortical motor system: a cortico-cortical evoked potential study Brain, January 1, 2007; 130(1): 181 - 197. [Abstract] [Full Text] [PDF]

				P. J. Uhlhaas, D. E. J. Linden, W. Singer, C. Haenschel, M. Lindner, K. Maurer, and E. Rodriguez Dysfunctional Long-Range Coordination of Neural Activity during Gestalt Perception in Schizophrenia J. Neurosci., August 2, 2006; 26(31): 8168 - 8175. [Abstract] [Full Text] [PDF]

				B. Pleger, F. Blankenburg, S. Bestmann, C. C. Ruff, K. Wiech, K. E. Stephan, K. J. Friston, and R. J. Dolan Repetitive Transcranial Magnetic Stimulation-Induced Changes in Sensorimotor Coupling Parallel Improvements of Somatosensation in Humans J. Neurosci., February 15, 2006; 26(7): 1945 - 1952. [Abstract] [Full Text] [PDF]

				P. Silberstein, A. Pogosyan, A. A. Kuhn, G. Hotton, S. Tisch, A. Kupsch, P. Dowsey-Limousin, M. I. Hariz, and P. Brown Cortico-cortical coupling in Parkinson's disease and its modulation by therapy Brain, June 1, 2005; 128(6): 1277 - 1291. [Abstract] [Full Text] [PDF]

				D. J. Serrien, M. Orth, A. H. Evans, A. J. Lees, and P. Brown Motor inhibition in patients with Gilles de la Tourette syndrome: functional activation patterns as revealed by EEG coherence Brain, January 1, 2005; 128(1): 116 - 125. [Abstract] [Full Text] [PDF]

				S. Ohara, N. E. Crone, N. Weiss, R.-D. Treede, and F. A. Lenz Cutaneous Painful Laser Stimuli Evoke Responses Recorded Directly From Primary Somatosensory Cortex in Awake Humans J Neurophysiol, June 1, 2004; 91(6): 2734 - 2746. [Abstract] [Full Text] [PDF]

				D. Lee Behavioral Context and Coherent Oscillations in the Supplementary Motor Area J. Neurosci., May 5, 2004; 24(18): 4453 - 4459. [Abstract] [Full Text] [PDF]

				B. Pollok, J. Gross, M. Dirks, L. Timmermann, and A. Schnitzler The cerebral oscillatory network of voluntary tremor J. Physiol., February 1, 2004; 554(3): 871 - 878. [Abstract] [Full Text] [PDF]

				D. Lee Coherent Oscillations in Neuronal Activity of the Supplementary Motor Area during a Visuomotor Task J. Neurosci., July 30, 2003; 23(17): 6798 - 6809. [Abstract] [Full Text] [PDF]

				A. Stancak, E. R. Cohen, R. D. Seidler, T. Q. Duong, and S.-G. Kim The Size of Corpus Callosum Correlates with Functional Activation of Medial Motor Cortical Areas in Bimanual and Unimanual Movements Cereb Cortex, May 1, 2003; 13(5): 475 - 485. [Abstract] [Full Text] [PDF]

				D. Kubota, L. L. Colgin, M. Casale, F. A. Brucher, and G. Lynch Endogenous Waves in Hippocampal Slices J Neurophysiol, January 1, 2003; 89(1): 81 - 89. [Abstract] [Full Text] [PDF]

				J. A. Goldberg, T. Boraud, S. Maraton, S. N. Haber, E. Vaadia, and H. Bergman Enhanced Synchrony among Primary Motor Cortex Neurons in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Primate Model of Parkinson's Disease J. Neurosci., June 1, 2002; 22(11): 4639 - 4653. [Abstract] [Full Text] [PDF]

				L. Timmermann, J. Gross, M. Dirks, J. Volkmann, H.-J. Freund, and A. Schnitzler The cerebral oscillatory network of parkinsonian resting tremor Brain, January 1, 2002; 126(1): 199 - 212. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help