 |
||||
|
||||
|
||||
|
||||
Previous Article | Next Article
The Journal of Neuroscience, December 15, 2001, 21(24):9904-9916
Adaptation to Temporal Contrast in Primate and Salamander Retina
Divya Chander and E. J. Chichilnisky Systems Neurobiology, The Salk Institute, La Jolla, California 92037-1099
Visual adaptation to temporal contrast (intensity modulation of a spatially uniform, randomly flickering stimulus) was examined in simultaneously recorded ensembles of retinal ganglion cells (RGCs) in tiger salamander and macaque monkey retina. Slow contrast adaptation similar to that recently discovered in salamander and rabbit retina was observed in monkey retina. A novel method was developed to quantify the effect of temporal contrast on steady-state sensitivity and kinetics of light responses, separately from nonlinearities that would otherwise significantly contaminate estimates of sensitivity. Increases in stimulus contrast progressively and reversibly attenuated and sped light responses in both salamander and monkey RGCs, indicating that a portion of the contrast adaptation observed in visual cortex originates in the retina. The effect of adaptation on sensitivity and kinetics differed in simultaneously recorded populations of ON and OFF cells. In salamander, adaptation affected the sensitivity of OFF cells more than ON cells. In monkey, adaptation affected the sensitivity of ON cells more than OFF cells. In both species, adaptation sped the light responses of OFF cells more than ON cells. Functionally defined subclasses of ON and OFF cells also exhibited asymmetric adaptation. These findings indicate that contrast adaptation differs in parallel retinal circuits that convey distinct visual signals to the brain.
Key words: retinal ganglion cell; salamander; primate; retina; contrast; temporal contrast; adaptation; gain; sensitivity; nonlinear; white noise
Copyright © 2001 Society for Neuroscience 0270-6474/01/21249904-13$05.00/0
This article has been cited by other articles:
T. O. Sharpee, K. D. Miller, and M. P. Stryker
On the Importance of Static Nonlinearity in Estimating Spatiotemporal Neural Filters With Natural Stimuli
J Neurophysiol, May 1, 2008; 99(5): 2496 - 2509.
[Abstract] [Full Text] [PDF]
D. Kerschensteiner, H. Liu, C. W. Cheng, J. Demas, S. H. Cheng, C.-c. Hui, R. L. Chow, and R. O. L. Wong
Genetic Control of Circuit Function: Vsx1 and Irx5 Transcription Factors Regulate Contrast Adaptation in the Mouse Retina
J. Neurosci., March 5, 2008; 28(10): 2342 - 2352.
[Abstract] [Full Text] [PDF]
T. Duong and R. D. Freeman
Contrast Sensitivity Is Enhanced by Expansive Nonlinear Processing in the Lateral Geniculate Nucleus
J Neurophysiol, January 1, 2008; 99(1): 367 - 372.
[Abstract] [Full Text] [PDF]
A. B. Abrams, J. M. Hillis, and D. H. Brainard
The Relation Between Color Discrimination and Color Constancy: When Is Optimal Adaptation Task Dependent?
Neural Comput., October 1, 2007; 19(10): 2610 - 2637.
[Abstract] [Full Text] [PDF]
L. A. J. Reiss, S. Bandyopadhyay, and E. D. Young
Effects of Stimulus Spectral Contrast on Receptive Fields of Dorsal Cochlear Nucleus Neurons
J Neurophysiol, October 1, 2007; 98(4): 2133 - 2143.
[Abstract] [Full Text] [PDF]
K. S. Gaudry and P. Reinagel
Contrast Adaptation in a Nonadapting LGN Model
J Neurophysiol, September 1, 2007; 98(3): 1287 - 1296.
[Abstract] [Full Text] [PDF]
K. S. Gaudry and P. Reinagel
Benefits of Contrast Normalization Demonstrated in Neurons and Model Cells
J. Neurosci., July 25, 2007; 27(30): 8071 - 8079.
[Abstract] [Full Text] [PDF]
D. L. Ringach and B. J. Malone
The Operating Point of the Cortex: Neurons as Large Deviation Detectors
J. Neurosci., July 18, 2007; 27(29): 7673 - 7683.
[Abstract] [Full Text] [PDF]
K. A. Zaghloul, M. B. Manookin, B. G. Borghuis, K. Boahen, and J. B. Demb
Functional Circuitry for Peripheral Suppression in Mammalian Y-Type Retinal Ganglion Cells
J Neurophysiol, June 1, 2007; 97(6): 4327 - 4340.
[Abstract] [Full Text] [PDF]
A. Kohn
Visual Adaptation: Physiology, Mechanisms, and Functional Benefits
J Neurophysiol, May 1, 2007; 97(5): 3155 - 3164.
[Abstract] [Full Text] [PDF]
D. L. Beaudoin, B. G. Borghuis, and J. B. Demb
Cellular Basis for Contrast Gain Control over the Receptive Field Center of Mammalian Retinal Ganglion Cells
J. Neurosci., March 7, 2007; 27(10): 2636 - 2645.
[Abstract] [Full Text] [PDF]
S. G. Solomon, B. B. Lee, and H. Sun
Suppressive surrounds and contrast gain in magnocellular-pathway retinal ganglion cells of macaque.
J. Neurosci., August 23, 2006; 26(34): 8715 - 8726.
[Abstract] [Full Text] [PDF]
V. Bonin, V. Mante, and M. Carandini
The statistical computation underlying contrast gain control.
J. Neurosci., June 7, 2006; 26(23): 6346 - 6353.
[Abstract] [Full Text] [PDF]
N. A. Crowder, N.S.C. Price, M. A. Hietanen, B. Dreher, C.W.G. Clifford, and M. R. Ibbotson
Relationship Between Contrast Adaptation and Orientation Tuning in V1 and V2 of Cat Visual Cortex
J Neurophysiol, January 1, 2006; 95(1): 271 - 283.
[Abstract] [Full Text] [PDF]
V. Bonin, V. Mante, and M. Carandini
The Suppressive Field of Neurons in Lateral Geniculate Nucleus
J. Neurosci., November 23, 2005; 25(47): 10844 - 10856.
[Abstract] [Full Text] [PDF]
J. W. Pillow, L. Paninski, V. J. Uzzell, E. P. Simoncelli, and E. J. Chichilnisky
Prediction and Decoding of Retinal Ganglion Cell Responses with a Probabilistic Spiking Model
J. Neurosci., November 23, 2005; 25(47): 11003 - 11013.
[Abstract] [Full Text] [PDF]
M. Carandini, J. B. Demb, V. Mante, D. J. Tolhurst, Y. Dan, B. A. Olshausen, J. L. Gallant, and N. C. Rust
Do We Know What the Early Visual System Does?
J. Neurosci., November 16, 2005; 25(46): 10577 - 10597.
[Abstract] [Full Text] [PDF]
M. R. Ibbotson
Contrast and Temporal Frequency-Related Adaptation in the Pretectal Nucleus of the Optic Tract
J Neurophysiol, July 1, 2005; 94(1): 136 - 146.
[Abstract] [Full Text] [PDF]
V. Porciatti, N. Sorokac, and W. Buchser
Habituation of Retinal Ganglion Cell Activity in Response to Steady State Pattern Visual Stimuli in Normal Subjects
Invest. Ophthalmol. Vis. Sci., April 1, 2005; 46(4): 1296 - 1302.
[Abstract] [Full Text] [PDF]
K. A. Zaghloul, K. Boahen, and J. B. Demb
Contrast Adaptation in Subthreshold and Spiking Responses of Mammalian Y-Type Retinal Ganglion Cells
J. Neurosci., January 26, 2005; 25(4): 860 - 868.
[Abstract] [Full Text] [PDF]
T. Gollisch and A. V. M. Herz
Input-Driven Components of Spike-Frequency Adaptation Can Be Unmasked In Vivo
J. Neurosci., August 25, 2004; 24(34): 7435 - 7444.
[Abstract] [Full Text] [PDF]
S. Shady, D. I. A. MacLeod, and H. S. Fisher
Adaptation from invisible flicker
PNAS, April 6, 2004; 101(14): 5170 - 5173.
[Abstract] [Full Text] [PDF]
X.-J. Wang, Y. Liu, M. V. Sanchez-Vives, and D. A. McCormick
Adaptation and Temporal Decorrelation by Single Neurons in the Primary Visual Cortex
J Neurophysiol, June 1, 2003; 89(6): 3279 - 3293.
[Abstract] [Full Text] [PDF]
N. K. Dhingra, Y.-H. Kao, P. Sterling, and R. G. Smith
Contrast Threshold of a Brisk-Transient Ganglion Cell In Vitro
J Neurophysiol, May 1, 2003; 89(5): 2360 - 2369.
[Abstract] [Full Text] [PDF]
K. A. Zaghloul, K. Boahen, and J. B. Demb
Different Circuits for ON and OFF Retinal Ganglion Cells Cause Different Contrast Sensitivities
J. Neurosci., April 1, 2003; 23(7): 2645 - 2654.
[Abstract] [Full Text] [PDF]
K. J. Kim and F. Rieke
Slow Na+ Inactivation and Variance Adaptation in Salamander Retinal Ganglion Cells
J. Neurosci., February 15, 2003; 23(4): 1506 - 1516.
[Abstract] [Full Text] [PDF]
E. J. Chichilnisky and R. S. Kalmar
Functional Asymmetries in ON and OFF Ganglion Cells of Primate Retina
J. Neurosci., April 1, 2002; 22(7): 2737 - 2747.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|