 |
|||||
|
|||||
|
|||||
|
|||||
|
|||||
Previous Article | Next Article
The Journal of Neuroscience, August 1, 2002, 22(15):6800-6809
Modular Organization of Turtle Spinal Interneurons during Normal and Deletion Fictive Rostral Scratching
Paul S. G. Stein and Susan Daniels-McQueen Department of Biology, Washington University, St. Louis, Missouri 63130
During normal rostral scratching in the spinal turtle, there is rhythmic alternation between hip-flexor and hip-extensor motor activity. During rostral scratching with hip-extensor deletions, there are successive bursts of hip-flexor motor activity and no activity in hip-extensor motor neurons. We characterized the ON- and OFF-phases of 72 descending propriospinal interneurons with distinct activity bursts during normal rostral scratching. We also studied the activity of these interneurons during deletion scratching. Hip-extensor interneurons were active when hip-flexor motor neurons were quiet in normal scratching and had zero overlap with hip-flexor motor activity. This population of hip-extensor interneurons, termed the hip-extensor module or hip-extensor unit-burst generator, was mainly quiet during deletion scratching. Our observation supports the concept that a module is a neuronal population that may be active or quiet in a coordinated manner during a spinal motor rhythm. During normal scratching, hip-flexor interneurons were active during hip-flexor motor activity, and spanning interneurons were active during both hip-flexor motor activity and quiescence. Hip-flexor and spanning interneurons with intermediate overlap with hip-flexor motor activity fired in bursts during deletion scratching. Hip-flexor and spanning interneurons with large overlap with hip-flexor motor activity fired continuously during deletion scratching. Key features of hip-flexor and spanning interneuron firing during normal scratching were preserved during deletion scratching. Thus these features do not require activity in the hip-extensor module in every cycle of a motor rhythm.
Key words: spinal cord; scratch reflex; half-center; central pattern generator; turtle; reciprocal inhibition; fictive motor patterns
Copyright © 2002 Society for Neuroscience 0270-6474/02/22156800-10$05.00/0
This article has been cited by other articles:
D. A. Klein, A. Patino, and M. C. Tresch
Flexibility of Motor Pattern Generation Across Stimulation Conditions by the Neonatal Rat Spinal Cord
J Neurophysiol, March 1, 2010; 103(3): 1580 - 1590.
[Abstract] [Full Text] [PDF]
C. B. Hart and S. F. Giszter
A Neural Basis for Motor Primitives in the Spinal Cord
J. Neurosci., January 27, 2010; 30(4): 1322 - 1336.
[Abstract] [Full Text] [PDF]
N. S. Bradley, Y. U. Ryu, and J. Lin
Fast Locomotor Burst Generation in Late Stage Embryonic Motility
J Neurophysiol, April 1, 2008; 99(4): 1733 - 1742.
[Abstract] [Full Text] [PDF]
Y. P. Ivanenko, G. Cappellini, N. Dominici, R. E. Poppele, and F. Lacquaniti
Modular Control of Limb Movements during Human Locomotion
J. Neurosci., October 10, 2007; 27(41): 11149 - 11161.
[Abstract] [Full Text] [PDF]
N. Krouchev, J. F. Kalaska, and T. Drew
Sequential Activation of Muscle Synergies During Locomotion in the Intact Cat as Revealed by Cluster Analysis and Direct Decomposition
J Neurophysiol, October 1, 2006; 96(4): 1991 - 2010.
[Abstract] [Full Text] [PDF]
H. Nishimaru, C. E. Restrepo, and O. Kiehn
Activity of Renshaw cells during locomotor-like rhythmic activity in the isolated spinal cord of neonatal mice.
J. Neurosci., May 17, 2006; 26(20): 5320 - 5328.
[Abstract] [Full Text] [PDF]
M. G. Sirota, G. A. Pavlova, and I. N. Beloozerova
Activity of the Motor Cortex During Scratching
J Neurophysiol, February 1, 2006; 95(2): 753 - 765.
[Abstract] [Full Text] [PDF]
B. Mulloney, P. I. Harness, and W. M. Hall
Bursts of Information: Coordinating Interneurons Encode Multiple Parameters of a Periodic Motor Pattern
J Neurophysiol, February 1, 2006; 95(2): 850 - 861.
[Abstract] [Full Text] [PDF]
A. Berkowitz
Physiology and Morphology Indicate That Individual Spinal Interneurons Contribute to Diverse Limb Movements
J Neurophysiol, December 1, 2005; 94(6): 4455 - 4470.
[Abstract] [Full Text] [PDF]
P. Saltiel, K. Wyler-Duda, A. d'Avella, R. J. Ajemian, and E. Bizzi
Localization and Connectivity in Spinal Interneuronal Networks: The Adduction-Caudal Extension-Flexion Rhythm in the Frog
J Neurophysiol, September 1, 2005; 94(3): 2120 - 2138.
[Abstract] [Full Text] [PDF]
M. Lafreniere-Roula and D. A. McCrea
Deletions of Rhythmic Motoneuron Activity During Fictive Locomotion and Scratch Provide Clues to the Organization of the Mammalian Central Pattern Generator
J Neurophysiol, August 1, 2005; 94(2): 1120 - 1132.
[Abstract] [Full Text] [PDF]
J. F. Yang, E. V. Lamont, and M. Y. C. Pang
Split-Belt Treadmill Stepping in Infants Suggests Autonomous Pattern Generators for the Left and Right Leg in Humans
J. Neurosci., July 20, 2005; 25(29): 6869 - 6876.
[Abstract] [Full Text] [PDF]
A. Alaburda, R. Russo, N. MacAulay, and J. Hounsgaard
Periodic High-Conductance States in Spinal Neurons during Scratch-Like Network Activity in Adult Turtles
J. Neurosci., July 6, 2005; 25(27): 6316 - 6321.
[Abstract] [Full Text] [PDF]
J. Jing, E. C. Cropper, I. Hurwitz, and K. R. Weiss
The Construction of Movement with Behavior-Specific and Behavior-Independent Modules
J. Neurosci., July 14, 2004; 24(28): 6315 - 6325.
[Abstract] [Full Text] [PDF]
C. B. Hart and S. F. Giszter
Modular Premotor Drives and Unit Bursts as Primitives for Frog Motor Behaviors
J. Neurosci., June 2, 2004; 24(22): 5269 - 5282.
[Abstract] [Full Text] [PDF]
P. S. G. Stein and S. Daniels-McQueen
Variations in Motor Patterns During Fictive Rostral Scratching in the Turtle: Knee-Related Deletions
J Neurophysiol, May 1, 2004; 91(5): 2380 - 2384.
[Abstract] [Full Text] [PDF]
P. S.G. Stein and S. Daniels-McQueen
Timing of Knee-Related Spinal Neurons During Fictive Rostral Scratching in the Turtle
J Neurophysiol, December 1, 2003; 90(6): 3585 - 3593.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|