QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

The Journal of Neuroscience, December 17, 2003, 23(37):11516-11522

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (32) Citing Articles via Google Scholar Google Scholar Articles by Devlin, J. T. Articles by Moore, D. R. Search for Related Content PubMed PubMed Citation Articles by Devlin, J. T. Articles by Moore, D. R.

 Previous Article  |  Next Article 

Behavioral/Systems/Cognitive
Functional Asymmetry for Auditory Processing in Human Primary Auditory Cortex

Joseph T. Devlin,¹ Josephine Raley,¹ Elizabeth Tunbridge,¹ Katherine Lanary,¹ Anna Floyer-Lea,¹ Charvy Narain,¹ Ian Cohen,¹ Timothy Behrens,¹ Peter Jezzard,¹ Paul M. Matthews,¹ and David R. Moore²

¹Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom, and ²Medical Research Council Institute of Hearing Research, University Park, Nottingham NG7 2RD, United Kingdom

Structural asymmetries in the supratemporal plane of the human brain are often cited as the anatomical basis for the lateralization of language predominantly to the left hemisphere. However, similar asymmetries are found for structures mediating earlier events in the auditory processing stream, suggesting that functional lateralization may occur even at the level of primary auditory cortex. We tested this hypothesis using functional magnetic resonance imaging to evaluate human auditory cortex responses to monaurally presented tones. Relative to silence, tones presented separately to either ear produced greater activation in left than right Heschl's gyrus, the location of primary auditory cortex. This functional lateralization for primary auditory cortex is distinct from the contralateral dominance reported for other mammals, including nonhuman primates, and may have contributed to the evolution of a unique role for the left hemisphere in language processing.

Key words: auditory; lateralization; hemisphere; imaging; sensory neurons; speech

---

Received July 3, 2003; revised October 11, 2003; accepted October 15, 2003.

This article has been cited by other articles:

				E. J. Propst, J. H. Greinwald, and V. Schmithorst Neuroanatomic Differences in Children With Unilateral Sensorineural Hearing Loss Detected Using Functional Magnetic Resonance Imaging Arch Otolaryngol Head Neck Surg, January 1, 2010; 136(1): 22 - 26. [Abstract] [Full Text] [PDF]

				N. Shea, K. Krug, and P. N. Tobler Conceptual representations in goal-directed decision making Cogn Affect Behav Neurosci, December 1, 2008; 8(4): 418 - 428. [Abstract] [PDF]

				Y. Y. Choi, N. A. Shamosh, S. H. Cho, C. G. DeYoung, M. J. Lee, J.-M. Lee, S. I. Kim, Z.-H. Cho, K. Kim, J. R. Gray, et al. Multiple Bases of Human Intelligence Revealed by Cortical Thickness and Neural Activation J. Neurosci., October 8, 2008; 28(41): 10323 - 10329. [Abstract] [Full Text] [PDF]

				P. C. M. Wong, A. K. Uppunda, T. B. Parrish, and S. Dhar Cortical Mechanisms of Speech Perception in Noise J Speech Lang Hear Res, August 1, 2008; 51(4): 1026 - 1041. [Abstract] [Full Text] [PDF]

				M. K. Ray, C. E. Mackay, C. J. Harmer, and T. J. Crow Bilateral Generic Working Memory Circuit Requires Left-Lateralized Addition for Verbal Processing Cereb Cortex, June 1, 2008; 18(6): 1421 - 1428. [Abstract] [Full Text] [PDF]

				A. Widmann, T. Gruber, T. Kujala, M. Tervaniemi, and E. Schroger Binding Symbols and Sounds: Evidence from Event-Related Oscillatory Gamma-Band Activity Cereb Cortex, November 1, 2007; 17(11): 2696 - 2702. [Abstract] [Full Text] [PDF]

				M. Schonwiesner, K. Krumbholz, R. Rubsamen, G. R. Fink, and D. Y. von Cramon Hemispheric Asymmetry for Auditory Processing in the Human Auditory Brain Stem, Thalamus, and Cortex Cereb Cortex, February 1, 2007; 17(2): 492 - 499. [Abstract] [Full Text] [PDF]

				M. Chait, D. Poeppel, and J. Z. Simon Neural Response Correlates of Detection of Monaurally and Binaurally Created Pitches in Humans Cereb Cortex, June 1, 2006; 16(6): 835 - 848. [Abstract] [Full Text] [PDF]

				B. Ross, A.T. Herdman, and C. Pantev Right Hemispheric Laterality of Human 40 Hz Auditory Steady-state Responses Cereb Cortex, December 1, 2005; 15(12): 2029 - 2039. [Abstract] [Full Text] [PDF]

				N. Behne, H. Scheich, and A. Brechmann Contralateral White Noise Selectively Changes Right Human Auditory Cortex Activity Caused by a FM-Direction Task J Neurophysiol, January 1, 2005; 93(1): 414 - 423. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help