 |
|||||
|
|||||
|
|||||
|
|||||
|
|||||
The Journal of Neuroscience, October 6, 2004, 24(40):8847-8852; doi:10.1523/JNEUROSCI.2513-04.2004
Previous Article | Next Article
Behavioral/Systems/Cognitive
Selection for Cognitive Control: A Functional Magnetic Resonance Imaging Study on the Selection of Task-Relevant Information
Marcel Brass andD. Yves von Cramon Max Planck Institute for Human Cognitive and Brain Sciences, Department of Cognitive Neurology, 04103 Leipzig, Germany
The complex environment we live in makes it necessary to distinguish relevant from irrelevant information constantly and reliably. The aim of the present study was to investigate the neural substrate underlying the selection of task-relevant information. We devised a new paradigm in which participants had to switch between two different tasks that were instructed by task cues. The task cues had a relevant and an irrelevant cue dimension. In congruent trials, both cue dimensions indicated the same task; in incongruent trials, they indicated different tasks; and in neutral trials, only the relevant dimension indicated a task. By comparing trials in which both cue dimensions were informative (congruent and incongruent trials) with trials in which only the relevant dimension was informative (neutral trials), we were able to show that the lateral prefrontal cortex and a region in the intraparietal sulcus are involved in the selection of task-relevant information. Furthermore, the present paradigm allows the influence of the selected task and stimulus dimension to be investigated. No significant influence was found in the prefrontal cortex, indicating that this region serves a very abstract role in the selection of task-relevant information.
Key words: cognitive control; task selection; fMRI; task switching; prefrontal cortex; intraparietal sulcus
Received March 1, 2004; revised August 19, 2004; accepted August 20, 2004.
This article has been cited by other articles:
C. R. Rosenthal, E. E. Roche-Kelly, M. Husain, and C. Kennard
Response-Dependent Contributions of Human Primary Motor Cortex and Angular Gyrus to Manual and Perceptual Sequence Learning
J. Neurosci., December 2, 2009; 29(48): 15115 - 15125.
[Abstract] [Full Text] [PDF]
S. Graham, J. Jiang, V. Manning, A. B. Nejad, K. Zhisheng, S. R. Salleh, X. Golay, Y. I. Berne, and P. J. McKenna
IQ-Related fMRI Differences during Cognitive Set Shifting
Cereb Cortex, July 1, 2009; (2009) bhp130v1.
[Abstract] [Full Text] [PDF]
S. W. Kennerley and J. D. Wallis
Reward-Dependent Modulation of Working Memory in Lateral Prefrontal Cortex
J. Neurosci., March 11, 2009; 29(10): 3259 - 3270.
[Abstract] [Full Text] [PDF]
J. Chikazoe, K. Jimura, T. Asari, K.-i. Yamashita, H. Morimoto, S. Hirose, Y. Miyashita, and S. Konishi
Functional Dissociation in Right Inferior Frontal Cortex during Performance of Go/No-Go Task
Cereb Cortex, January 1, 2009; 19(1): 146 - 152.
[Abstract] [Full Text] [PDF]
T. Jubault, C. Ody, and E. Koechlin
Serial Organization of Human Behavior in the Inferior Parietal Cortex
J. Neurosci., October 10, 2007; 27(41): 11028 - 11036.
[Abstract] [Full Text] [PDF]
J. Lepsien and A. C. Nobre
Attentional Modulation of Object Representations in Working Memory
Cereb Cortex, September 1, 2007; 17(9): 2072 - 2083.
[Abstract] [Full Text] [PDF]
D. T Stuss and M. P Alexander
Is there a dysexecutive syndrome?
Phil Trans R Soc B, May 29, 2007; 362(1481): 901 - 915.
[Abstract] [Full Text] [PDF]
M. P. Alexander, D. T. Stuss, T. Picton, T. Shallice, and S. Gillingham
Regional frontal injuries cause distinct impairments in cognitive control
Neurology, May 1, 2007; 68(18): 1515 - 1523.
[Abstract] [Full Text] [PDF]
A. N. Hampton and J. P. O'Doherty
Decoding the neural substrates of reward-related decision making with functional MRI
PNAS, January 23, 2007; 104(4): 1377 - 1382.
[Abstract] [Full Text] [PDF]
J. K. Roth, J. T. Serences, and S. M. Courtney
Neural System for Controlling the Contents of Object Working Memory in Humans
Cereb Cortex, November 1, 2006; 16(11): 1595 - 1603.
[Abstract] [Full Text] [PDF]
E. A. Crone, S. E. Donohue, R. Honomichl, C. Wendelken, and S. A. Bunge
Brain Regions Mediating Flexible Rule Use during Development
J. Neurosci., October 25, 2006; 26(43): 11239 - 11247.
[Abstract] [Full Text] [PDF]
D. Badre and A. D. Wagner
Computational and neurobiological mechanisms underlying cognitive flexibility
PNAS, May 2, 2006; 103(18): 7186 - 7191.
[Abstract] [Full Text] [PDF]
C. Cavina-Pratesi, K. F. Valyear, J. C. Culham, S. Kohler, S. S. Obhi, C. A. Marzi, and M. A. Goodale
Dissociating arbitrary stimulus-response mapping from movement planning during preparatory period: evidence from event-related functional magnetic resonance imaging.
J. Neurosci., March 8, 2006; 26(10): 2704 - 2713.
[Abstract] [Full Text] [PDF]
J. C. Snow and J. B. Mattingley
Goal-driven selective attention in patients with right hemisphere lesions: how intact is the ipsilesional field?
Brain, January 1, 2006; 129(1): 168 - 181.
[Abstract] [Full Text] [PDF]
S. Konishi, J. Chikazoe, K. Jimura, T. Asari, and Y. Miyashita
Neural mechanism in anterior prefrontal cortex for inhibition of prolonged set interference
PNAS, August 30, 2005; 102(35): 12584 - 12588.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|