WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience Seahorse Bioscience
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
The Journal of Neuroscience, November 17, 2004, 24(46):10488-10492; doi:10.1523/JNEUROSCI.2984-04.2004

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (14)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gruest, N.
Right arrow Articles by Hars, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gruest, N.
Right arrow Articles by Hars, B.

 Previous Article  |  Next Article 

BRIEF COMMUNICATION
Memory Consolidation and Reconsolidation in the Rat Pup Require Protein Synthesis

Nadège Gruest, Paulette Richer, and Bernard Hars

Laboratoire de Neurobiologie de l'Apprentissage, de la Mémoire, et de la Communication, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8620, Université Paris-sud, 91405 Orsay Cedex, France

Little is known about the ontogenesis of memory, whether it appears with its full characteristics or whether they emerge progressively with development. In the adult, basic characteristics of memory processing are consolidation of memory after acquisition and reconsolidation after retrieval. Here, using a conditioned aversion paradigm and postlearning or postreactivation injection of a protein synthesis inhibitor, we show that memory acquired by rat pups as early as postnatal day 3 requires time-dependent protein synthesis after both learning and reactivation. These results present the first evidence suggesting that consolidation and reconsolidation are original properties of memory function.

Key words: memory; consolidation; reconsolidation; protein synthesis; conditioned aversion; rat pup

Received July 22, 2004; revised October 11, 2004; accepted October 11, 2004.




This article has been cited by other articles:


Home page
 Learn. Mem.Home page
S. Languille, N. Gruest, P. Richer, and B. Hars
The temporal dynamics of consolidation and reconsolidation decrease during postnatal development
Learn. Mem., May 30, 2008; 15(6): 434 - 442.
[Abstract] [Full Text] [PDF]

Home page
 Learn. Mem.Home page
K. Shionoya, S. Moriceau, L. Lunday, C. Miner, T. L. Roth, and R. M. Sullivan
Development switch in neural circuitry underlying odor-malaise learning
Learn. Mem., November 1, 2006; 13(6): 801 - 808.
[Abstract] [Full Text] [PDF]

Home page
 Learn. Mem.Home page
S. J. Sara and B. Hars
In memory of consolidation.
Learn. Mem., September 1, 2006; 13(5): 515 - 521.
[Full Text] [PDF]

Home page
 Learn. Mem.Home page
C. Bucherelli, E. Baldi, C. Mariottini, M. B. Passani, and P. Blandina
Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation
Learn. Mem., July 1, 2006; 13(4): 426 - 430.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Colon-Cesario, J. Wang, X. Ramos, H. G. Garcia, J. J. Davila, J. Laguna, C. Rosado, and S. Pena de Ortiz
An inhibitor of DNA recombination blocks memory consolidation, but not reconsolidation, in context fear conditioning.
J. Neurosci., May 17, 2006; 26(20): 5524 - 5533.
[Abstract] [Full Text] [PDF]


-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2008 by Society for Neuroscience ONLINE ISSN: 1529-2401
-