QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

The Journal of Neuroscience, November 9, 2005, 25(45):10494-10501; doi:10.1523/JNEUROSCI.1227-05.2005

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (34) Citing Articles via Google Scholar Google Scholar Articles by Haenschel, C. Articles by Baldeweg, T. Search for Related Content PubMed PubMed Citation Articles by Haenschel, C. Articles by Baldeweg, T. Pubmed/NCBI databases Medline Plus Health Information Memory

 Previous Article  |  Next Article 

Behavioral/Systems/Cognitive
Event-Related Brain Potential Correlates of Human Auditory Sensory Memory-Trace Formation

Corinna Haenschel,^1,2 David J. Vernon,³ Prabuddh Dwivedi,⁴ John H. Gruzelier,⁴ and Torsten Baldeweg⁵

¹Laboratory for Neurophysiology and Neuroimaging, Department of Psychiatry, Johann Wolfgang Goethe University, 60590 Frankfurt, Germany, ²Max Planck Institute for Brain Research, 60528 Frankfurt, Germany, ³Department of Applied Social Sciences, Canterbury Christ Church University College, Canterbury CT1 1QU, United Kingdom, ⁴Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College, London W6 8RP, United Kingdom, and ⁵Institute of Child Health, University College London and Great Ormond Street Hospital for Children, London WC1N 1EH, United Kingdom

The event-related potential (ERP) component mismatch negativity (MMN) is a neural marker of human echoic memory. MMN is elicited by deviant sounds embedded in a stream of frequent standards, reflecting the deviation from an inferred memory trace of the standard stimulus. The strength of this memory trace is thought to be proportional to the number of repetitions of the standard tone, visible as the progressive enhancement of MMN with number of repetitions (MMN memory-trace effect). However, no direct ERP correlates of the formation of echoic memory traces are currently known. This study set out to investigate changes in ERPs to different numbers of repetitions of standards, delivered in a roving-stimulus paradigm in which the frequency of the standard stimulus changed randomly between stimulus trains. Normal healthy volunteers (n = 40) were engaged in two experimental conditions: during passive listening and while actively discriminating changes in tone frequency. As predicted, MMN increased with increasing number of standards. However, this MMN memory-trace effect was caused mainly by enhancement with stimulus repetition of a slow positive wave from 50 to 250 ms poststimulus in the standard ERP, which is termed here "repetition positivity" (RP). This RP was recorded from frontocentral electrodes when participants were passively listening to or actively discriminating changes in tone frequency. RP may represent a human ERP correlate of rapid and stimulus-specific adaptation, a candidate neuronal mechanism underlying sensory memory formation in the auditory cortex.

Key words: event-related potentials; mismatch negativity; echoic memory; audition; sensory memory; human

---

Received March 30, 2005; revised September 22, 2005; accepted October 6, 2005.

This article has been cited by other articles:

				W. von der Behrens, P. Bauerle, M. Kossl, and B. H. Gaese Correlating Stimulus-Specific Adaptation of Cortical Neurons and Local Field Potentials in the Awake Rat J. Neurosci., November 4, 2009; 29(44): 13837 - 13849. [Abstract] [Full Text] [PDF]

				A. Bendixen, E. Schroger, and I. Winkler I Heard That Coming: Event-Related Potential Evidence for Stimulus-Driven Prediction in the Auditory System J. Neurosci., July 1, 2009; 29(26): 8447 - 8451. [Abstract] [Full Text] [PDF]

				B. J. DYSON and C. ALAIN It all sounds the same to me: Sequential ERP and behavioral effects during pitch and harmonicity judgments Cogn Affect Behav Neurosci, September 1, 2008; 8(3): 329 - 343. [Abstract] [PDF]

				C. Haenschel, R. A. Bittner, F. Haertling, A. Rotarska-Jagiela, K. Maurer, W. Singer, and D. E. J. Linden Contribution of Impaired Early-Stage Visual Processing to Working Memory Dysfunction in Adolescents With Schizophrenia: A Study With Event-Related Potentials and Functional Magnetic Resonance Imaging Arch Gen Psychiatry, November 1, 2007; 64(11): 1229 - 1240. [Abstract] [Full Text] [PDF]

				M. Schonwiesner, N. Novitski, S. Pakarinen, S. Carlson, M. Tervaniemi, and R. Naatanen Heschl's Gyrus, Posterior Superior Temporal Gyrus, and Mid-Ventrolateral Prefrontal Cortex Have Different Roles in the Detection of Acoustic Changes J Neurophysiol, March 1, 2007; 97(3): 2075 - 2082. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help