QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

The Journal of Neuroscience, May 10, 2006, 26(19):5160-5166; doi:10.1523/JNEUROSCI.0350-06.2006

This Article Full Text Full Text (PDF) Supplemental data Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Related articles in J. Neurosci. Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (58) Citing Articles via Google Scholar Google Scholar Articles by Beaver, J. D. Articles by Calder, A. J. Search for Related Content PubMed PubMed Citation Articles by Beaver, J. D. Articles by Calder, A. J.

 Previous Article  |  Next Article 

Behavioral/Systems/Cognitive
Individual Differences in Reward Drive Predict Neural Responses to Images of Food

John D. Beaver,¹ Andrew D. Lawrence,¹ Jenneke van Ditzhuijzen,¹ Matt H. Davis,¹ Andrew Woods,² and Andrew J. Calder¹

¹Medical Research Council Cognition and Brain Sciences Unit, Cambridge CB2 2EF, United Kingdom, and ²School of Psychology, University of Wales, Bangor, Gwynedd LL57 2AS, United Kingdom

Correspondence should be addressed to either Dr. John Beaver or Dr. Andrew Calder, Medical Research Council Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK. Email: john.beaver{at}mrc-cbu.cam.ac.uk andy.calder{at}mrc-cbu.cam.ac.uk

A network of interconnected brain regions, including orbitofrontal, ventral striatal, amygdala, and midbrain areas, has been widely implicated in a number of aspects of food reward. However, in humans, sensitivity to reward can vary significantly from one person to the next. Individuals high in this trait experience more frequent and intense food cravings and are more likely to be overweight or develop eating disorders associated with excessive food intake. Using functional magnetic resonance imaging, we report that individual variation in trait reward sensitivity (as measured by the Behavioral Activation Scale) is highly correlated with activation to images of appetizing foods (e.g., chocolate cake, pizza) in a fronto–striatal–amygdala–midbrain network. Our findings demonstrate that there is considerable personality-linked variability in the neural response to food cues in healthy participants and provide important insight into the neurobiological factors underlying vulnerability to certain eating problems (e.g., hyperphagic obesity).

Key words: reward; personality; appetite; striatum; amygdala; orbitofrontal cortex

---

Received Jan. 25, 2006; revised March 21, 2006; accepted March 22, 2006.

Correspondence should be addressed to either Dr. John Beaver or Dr. Andrew Calder, Medical Research Council Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK. Email: john.beaver{at}mrc-cbu.cam.ac.uk andy.calder{at}mrc-cbu.cam.ac.uk

Related articles in J. Neurosci.:

Personality Predicts Responsivity of the Brain Reward System

Jan B. Engelmann
J. Neurosci. 2006 26: 7775-7776. [Full Text]  

This article has been cited by other articles:

				D. A. Van Vugt Brain imaging studies of appetite in the context of obesity and the menstrual cycle Hum. Reprod. Update, November 19, 2009; (2009) dmp051v1. [Abstract] [Full Text] [PDF]

				S. V. Mahler and K. C. Berridge Which Cue to "Want?" Central Amygdala Opioid Activation Enhances and Focuses Incentive Salience on a Prepotent Reward Cue J. Neurosci., May 20, 2009; 29(20): 6500 - 6513. [Abstract] [Full Text] [PDF]

				P. Schweinhardt, D. A. Seminowicz, E. Jaeger, G. H. Duncan, and M. C. Bushnell The Anatomy of the Mesolimbic Reward System: A Link between Personality and the Placebo Analgesic Response J. Neurosci., April 15, 2009; 29(15): 4882 - 4887. [Abstract] [Full Text] [PDF]

				L. Passamonti, J. B. Rowe, C. Schwarzbauer, M. P. Ewbank, E. von dem Hagen, and A. J. Calder Personality Predicts the Brain's Response to Viewing Appetizing Foods: The Neural Basis of a Risk Factor for Overeating J. Neurosci., January 7, 2009; 29(1): 43 - 51. [Abstract] [Full Text] [PDF]

				R. Cilia, C. Siri, G. Marotta, I. U. Isaias, D. De Gaspari, M. Canesi, G. Pezzoli, and A. Antonini Functional Abnormalities Underlying Pathological Gambling in Parkinson Disease Arch Neurol, December 1, 2008; 65(12): 1604 - 1611. [Abstract] [Full Text] [PDF]

				N. Cherbuin, T. D. Windsor, K. J. Anstey, J. J. Maller, C. Meslin, and P. S. Sachdev Hippocampal volume is positively associated with behavioural inhibition (BIS) in a large community-based sample of mid-life adults: the PATH through life study Soc Cogn Affect Neurosci, September 1, 2008; 3(3): 262 - 269. [Abstract] [Full Text] [PDF]

				P. A. Hall, M. J. Coons, and T. M. Vallis Anxious Temperament and Disease Progression at Diagnosis: The Case of Type 2 Diabetes Psychosom Med, September 1, 2008; 70(7): 837 - 843. [Abstract] [Full Text] [PDF]

				J. D. Beaver, A. D. Lawrence, L. Passamonti, and A. J. Calder Appetitive Motivation Predicts the Neural Response to Facial Signals of Aggression J. Neurosci., March 12, 2008; 28(11): 2719 - 2725. [Abstract] [Full Text] [PDF]

				K. S. Smith and K. C. Berridge Opioid Limbic Circuit for Reward: Interaction between Hedonic Hotspots of Nucleus Accumbens and Ventral Pallidum J. Neurosci., February 14, 2007; 27(7): 1594 - 1605. [Abstract] [Full Text] [PDF]

				J. B. Engelmann Personality Predicts Responsivity of the Brain Reward System J. Neurosci., July 26, 2006; 26(30): 7775 - 7776. [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help