 |
|||||
|
|||||
|
|||||
|
|||||
|
|||||
The Journal of Neuroscience, July 26, 2006, 26(30):7791-7810; doi:10.1523/JNEUROSCI.0830-06.2006
Previous Article | Next Article
Behavioral/Systems/Cognitive
Control of Fast-Reaching Movements by Muscle Synergy Combinations
Andrea d'Avella,1 Alessandro Portone,1 Laure Fernandez,1 andFrancesco Lacquaniti1,2,3 1Department of Neuromotor Physiology, Santa Lucia Foundation, 00179 Rome, Italy, 2Department of Neuroscience, University of Rome Tor Vergata, 00133 Rome, Italy, and 3Center of Space Biomedicine, University of Rome Tor Vergata, 00179 Rome, Italy
Correspondence should be addressed to Dr. Andrea d'Avella, Dipartimento di Fisiologia Neuromotoria, Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy. a.davella{at}hsantalucia.it
How the CNS selects the appropriate muscle patterns to achieve a behavioral goal is an open question. To gain insight into this process, we characterized the spatiotemporal organization of the muscle patterns for fast-reaching movements. We recorded electromyographic activity from up to 19 shoulder and arm muscles during point-to-point movements between a central location and 8 peripheral targets in each of 2 vertical planes. We used an optimization algorithm to identify a set of time-varying muscle synergies, i.e., the coordinated activations of groups of muscles with specific time-varying profiles. For each one of nine subjects, we extracted four or five synergies whose combinations, after scaling in amplitude and shifting in time each synergy independently for each movement condition, explained 73–82% of the data variation. We then tested whether these synergies could reconstruct the muscle patterns for point-to-point movements with different loads or forearm postures and for reversal and via-point movements. We found that reconstruction accuracy remained high, indicating generalization across these conditions. Finally, the synergy amplitude coefficients were directionally tuned according to a cosine function with a preferred direction that showed a smaller variability with changes of load, posture, and endpoint than the preferred direction of individual muscles. Thus the complex spatiotemporal characteristics of the muscles patterns for reaching were captured by the combinations of a small number of components, suggesting that the mechanisms involved in the generation of the muscle patterns exploit this low dimensionality to simplify control.
Key words: motor control; arm; electromyography; optimization; decomposition; directional tuning; reversal; via-point
Received July 15, 2005; revised June 8, 2006; accepted June 9, 2006.
Correspondence should be addressed to Dr. Andrea d'Avella, Dipartimento di Fisiologia Neuromotoria, Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy. a.davella{at}hsantalucia.it
This article has been cited by other articles:
C. B. Hart and S. F. Giszter
A Neural Basis for Motor Primitives in the Spinal Cord
J. Neurosci., January 27, 2010; 30(4): 1322 - 1336.
[Abstract] [Full Text] [PDF]
W. J. Kargo, A. Ramakrishnan, C. B. Hart, L. C. Rome, and S. F. Giszter
A Simple Experimentally Based Model Using Proprioceptive Regulation of Motor Primitives Captures Adjusted Trajectory Formation in Spinal Frogs
J Neurophysiol, January 1, 2010; 103(1): 573 - 590.
[Abstract] [Full Text] [PDF]
M. A. Krutky, V. J. Ravichandran, R. D. Trumbower, and E. J. Perreault
Interactions Between Limb and Environmental Mechanics Influence Stretch Reflex Sensitivity in the Human Arm
J Neurophysiol, January 1, 2010; 103(1): 429 - 440.
[Abstract] [Full Text] [PDF]
C. Capaday, C. Ethier, L. Brizzi, A. Sik, C. van Vreeswijk, and D. Gingras
On the Nature of the Intrinsic Connectivity of the Cat Motor Cortex: Evidence for a Recurrent Neural Network Topology
J Neurophysiol, October 1, 2009; 102(4): 2131 - 2141.
[Abstract] [Full Text] [PDF]
A. Reichenbach, A. Thielscher, A. Peer, H. H. Bülthoff, and J.-P. Bresciani
Seeing the hand while reaching speeds up on-line responses to a sudden change in target position
J. Physiol., October 1, 2009; 587(19): 4605 - 4616.
[Abstract] [Full Text] [PDF]
K. G. Keenan, V. J. Santos, M. Venkadesan, and F. J. Valero-Cuevas
Maximal Voluntary Fingertip Force Production Is Not Limited by Movement Speed in Combined Motion and Force Tasks
J. Neurosci., July 8, 2009; 29(27): 8784 - 8789.
[Abstract] [Full Text] [PDF]
F. J. Valero-Cuevas, M. Venkadesan, and E. Todorov
Structured Variability of Muscle Activations Supports the Minimal Intervention Principle of Motor Control
J Neurophysiol, July 1, 2009; 102(1): 59 - 68.
[Abstract] [Full Text] [PDF]
S. A. Winges, S. E. Eonta, J. F. Soechting, and M. Flanders
Effects of Object Compliance on Three-Digit Grasping
J Neurophysiol, May 1, 2009; 101(5): 2447 - 2458.
[Abstract] [Full Text] [PDF]
V. C. K. Cheung, A. d'Avella, and E. Bizzi
Adjustments of Motor Pattern for Load Compensation Via Modulated Activations of Muscle Synergies During Natural Behaviors
J Neurophysiol, March 1, 2009; 101(3): 1235 - 1257.
[Abstract] [Full Text] [PDF]
B. Berret, F. Bonnetblanc, C. Papaxanthis, and T. Pozzo
Modular Control of Pointing beyond Arm's Length
J. Neurosci., January 7, 2009; 29(1): 191 - 205.
[Abstract] [Full Text] [PDF]
J. Duchateau and R. M. Enoka
Neural control of shortening and lengthening contractions: influence of task constraints
J. Physiol., December 15, 2008; 586(24): 5853 - 5864.
[Abstract] [Full Text] [PDF]
A. d'Avella, L. Fernandez, A. Portone, and F. Lacquaniti
Modulation of Phasic and Tonic Muscle Synergies With Reaching Direction and Speed
J Neurophysiol, September 1, 2008; 100(3): 1433 - 1454.
[Abstract] [Full Text] [PDF]
C. P.H Elemans, R. Zaccarelli, and H. Herzel
Biomechanics and control of vocalization in a non-songbird
J R Soc Interface, July 6, 2008; 5(24): 691 - 703.
[Abstract] [Full Text] [PDF]
E. J. Perreault, K. Chen, R. D. Trumbower, and G. Lewis
Interactions With Compliant Loads Alter Stretch Reflex Gains But Not Intermuscular Coordination
J Neurophysiol, May 1, 2008; 99(5): 2101 - 2113.
[Abstract] [Full Text] [PDF]
S. A. Winges, S. E. Eonta, J. F. Soechting, and M. Flanders
Multi-Digit Control of Contact Forces During Rotation of a Hand-Held Object
J Neurophysiol, April 1, 2008; 99(4): 1846 - 1856.
[Abstract] [Full Text] [PDF]
Y. P. Ivanenko, A. d'Avella, R. E. Poppele, and F. Lacquaniti
On the Origin of Planar Covariation of Elevation Angles During Human Locomotion
J Neurophysiol, April 1, 2008; 99(4): 1890 - 1898.
[Abstract] [Full Text] [PDF]
W. J. Kargo and S. F. Giszter
Individual Premotor Drive Pulses, Not Time-Varying Synergies, Are the Units of Adjustment for Limb Trajectories Constructed in Spinal Cord
J. Neurosci., March 5, 2008; 28(10): 2409 - 2425.
[Abstract] [Full Text] [PDF]
S. A. Overduin, A. d'Avella, J. Roh, and E. Bizzi
Modulation of Muscle Synergy Recruitment in Primate Grasping
J. Neurosci., January 23, 2008; 28(4): 880 - 892.
[Abstract] [Full Text] [PDF]
G. Torres-Oviedo and L. H. Ting
Muscle Synergies Characterizing Human Postural Responses
J Neurophysiol, October 1, 2007; 98(4): 2144 - 2156.
[Abstract] [Full Text] [PDF]
S. A. Winges, J. F. Soechting, and M. Flanders
Multidigit Control of Contact Forces During Transport of Handheld Objects
J Neurophysiol, August 1, 2007; 98(2): 851 - 860.
[Abstract] [Full Text] [PDF]
L. Dipietro, H. I. Krebs, S. E. Fasoli, B. T. Volpe, J. Stein, C. Bever, and N. Hogan
Changing Motor Synergies in Chronic Stroke
J Neurophysiol, August 1, 2007; 98(2): 757 - 768.
[Abstract] [Full Text] [PDF]
|
|
|
|
 |
|