WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
The Journal of Neuroscience, March 14, 2007, 27(11):3010-3016; doi:10.1523/JNEUROSCI.5051-06.2007

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lungu, O. V.
Right arrow Articles by Carey, J. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lungu, O. V.
Right arrow Articles by Carey, J. R.

 Previous Article  |  Next Article 

Behavioral/Systems/Cognitive
Neural Changes in Control Implementation of a Continuous Task

Ovidiu V. Lungu,1,2 Meagan M. Binenstock,3 Megan A. Pline,3 Jennifer R. Yeaton,3 and James R. Carey3

1Brain Sciences Center, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, and 2Departments of Neuroscience and 3Physical Therapy, University of Minnesota, Minneapolis, Minnesota 55455

Correspondence should be addressed to Dr. Ovidiu V. Lungu, Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Room M-6814, 4565 Chemin Queen Mary, Montreal, Quebec, Canada H3W 1W5. Email: Ovidiu.Lungu{at}criugm.rtss.qc.ca

It is commonly agreed that control implementation, being a resource-consuming endeavor, is not exerted continuously or in simple tasks. However, most research in the field was done using tasks that varied the need for control on a trial-by-trial basis (e.g., Stroop, flanker) in a discrete manner. In this case, the anterior cingulate cortex (ACC) was found to monitor the need for control, whereas regions in the prefrontal cortex (PFC) were found to be involved in control implementation. Whether or not the same control mechanism would be used in continuous tasks was an open question. In our study, we found that in a continuous task, the same neural substrate subserves control monitoring (ACC) but that the neural substrate of control implementation changes over time. Early in the task, regions in the PFC were involved in control implementation, whereas later the control was taken over by subcortical structures, specifically the caudate. Our results suggest that humans possess a flexible control mechanism, with a specific structure dedicated to monitoring the need for control and with multiple structures involved in control implementation.

Key words: fMRI; cognitive control; ACC; DLPFC; caudate; adaptation

Received Nov. 21, 2006; revised Jan. 9, 2007; accepted Feb. 5, 2007.

Correspondence should be addressed to Dr. Ovidiu V. Lungu, Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Room M-6814, 4565 Chemin Queen Mary, Montreal, Quebec, Canada H3W 1W5. Email: Ovidiu.Lungu{at}criugm.rtss.qc.ca






-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2009 by Society for Neuroscience ONLINE ISSN: 1529-2401
-