WWW.JNEUROSCI.ORG
-
The Journal of Neuroscience
QUICK SEARCH:   [advanced]


     
-


HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP
The Journal of Neuroscience, May 21, 2008, 28(21):5539-5546; doi:10.1523/JNEUROSCI.5290-07.2008

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental Data
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Liu, T.
Right arrow Articles by Guo, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Liu, T.
Right arrow Articles by Guo, A.

 Previous Article  |  Next Article 

Behavioral/Systems/Cognitive
Increased Dopamine Level Enhances Male–Male Courtship in Drosophila

Tong Liu,1,2 Laurence Dartevelle,4 Chunyan Yuan,1 Hongping Wei,1,2 Ying Wang,1 Jean-François Ferveur,4 and Aike Guo1,3

1Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, 2Graduate School of Chinese Academy of Sciences, Beijing 100039, China, 3State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China, and 4Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5548, Universite de Bourgogne, Dijon 21000, France

Correspondence should be addressed to either of the following: Aike Guo, Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, Email: akguo{at}ion.ac.cn; or Jean-François Ferveur, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5548, Universite de Bourgogne, Dijon 21000, France, E-mail: Email: jean-francois.ferveur{at}u-bourgogne.fr

Sexual behavior between males is observed in many species, but the biological factors involved are poorly known. In mammals, manipulation of dopamine has revealed the role of this neuromodulator on male sexual behavior. We used genetic and pharmacological approaches to manipulate the dopamine level in dopaminergic cells in Drosophila and investigated the consequence of this manipulation on male–male courtship behavior. Males with increased dopamine level showed enhanced propensity to court other males but did not change their courtship toward virgin females, general olfactory response, general gustatory response, or locomotor activity. Our results indicate that the high intensity of male–male interaction shown by these manipulated males was related to their altered sensory perception of other males.

Key words: Drosophila; courtship; male–male courtship behavior; neurotransmitter; tyrosine hydroxylase; dopamine

Received Sept. 3, 2007; revised March 9, 2008; accepted April 14, 2008.

Correspondence should be addressed to either of the following: Aike Guo, Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, Email: akguo{at}ion.ac.cn; or Jean-François Ferveur, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5548, Universite de Bourgogne, Dijon 21000, France, E-mail: Email: jean-francois.ferveur{at}u-bourgogne.fr






 -
-

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help
-
Copyright 2009 by Society for Neuroscience ONLINE ISSN: 1529-2401
-