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The Journal of Neuroscience, October 14, 2009, 29(41):12717-12721; doi:10.1523/JNEUROSCI.3670-09.2009

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40th Anniversary Retrospective
Neurotransmitters, Receptors, and Second Messengers Galore in 40 Years

Solomon H. Snyder

Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21205

Correspondence should be addressed to Dr. Solomon H. Snyder, Johns Hopkins University, Department of Neuroscience, 725 N. Wolfe Street, WBSB 811, Baltimore, MD 21205. Email: ssnyder{at}bs.jhmi.edu

The past four decades have witnessed extraordinary advances in the molecular understanding of neurotransmitters, their receptors, and second messengers. This essay highlights a selected group of particular notable discoveries, emphasizing seminal findings that have transformed thinking in the field.


Received July 28, 2009; revised Aug. 7, 2009; accepted Aug. 12, 2009.

Correspondence should be addressed to Dr. Solomon H. Snyder, Johns Hopkins University, Department of Neuroscience, 725 N. Wolfe Street, WBSB 811, Baltimore, MD 21205. Email: ssnyder{at}bs.jhmi.edu






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