QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Margoliash, D. Search for Related Content PubMed PubMed Citation Articles by Margoliash, D.

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 3, 1039-1057, Copyright © 1983 by Society for Neuroscience

ARTICLE

Acoustic parameters underlying the responses of song-specific neurons in the white-crowned sparrow

D Margoliash

Songbirds such as the white-crowned sparrow memorize the song of conspecific adults during a critical period early in life and later in life develop song by utilizing auditory feedback. Neurons in one of the telencephalic nuclei controlling song have recently been shown to respond to acoustic stimuli. I investigated the auditory response properties of units in this nucleus using a technique that permitted great flexibility in manipulating complex stimuli such as song. A few of the units exhibited considerable selectivity for the individual's own song. In wild-caught birds, song-specific units exhibited intradialect selectivity. In those birds that sang abnormal songs due to laboratory manipulation of song exposure during the critical period for song learning, units were selective for the abnormal songs. By systematic modification of a song, and by construction of complex synthetic sounds mimicking song, the acoustic parameters responsible for the response selectivity were identified. Song-specific units responded to sequences of two song parts but not to the parts in isolation. Modification of the frequencies of either part of the sequence, or increasing the interval between the parts, varied the strength of the response. Thus, temporal as well as spectral parameters were important for the response. When sequences of synthetic sounds mimicking song were effective in evoking an excitatory response, the response was sensitive to the aforementioned manipulations. Wih these techniques it was possible to elucidate the acoustic parameters required to excite song-specific units. All songs of the repertoire eliciting a strong excitatory response contained the appropriate parameters, which were missing from all weakly effective, ineffective, or inhibitory songs.

This article has been cited by other articles:

				E. E. Bauer, M. J. Coleman, T. F. Roberts, A. Roy, J. F. Prather, and R. Mooney A Synaptic Basis for Auditory-Vocal Integration in the Songbird J. Neurosci., February 6, 2008; 28(6): 1509 - 1522. [Abstract] [Full Text] [PDF]

				J. A. Mossbridge, B. N. Scissors, and B. A. Wright Learning and generalization on asynchrony and order tasks at sound offset: Implications for underlying neural circuitry Learn. Mem., January 3, 2008; 15(1): 13 - 20. [Abstract] [Full Text] [PDF]

				S. S. Shaevitz and F. E. Theunissen Functional Connectivity Between Auditory Areas Field L and CLM and Song System Nucleus HVC in Anesthetized Zebra Finches J Neurophysiol, November 1, 2007; 98(5): 2747 - 2764. [Abstract] [Full Text] [PDF]

				S. Kojima and A. J. Doupe Song Selectivity in the Pallial-Basal Ganglia Song Circuit of Zebra Finches Raised Without Tutor Song Exposure J Neurophysiol, October 1, 2007; 98(4): 2099 - 2109. [Abstract] [Full Text] [PDF]

				S. R. Crandall, M. Adam, A. K. Kinnischtzke, and T. A. Nick HVC Neural Sleep Activity Increases With Development and Parallels Nightly Changes in Song Behavior J Neurophysiol, July 1, 2007; 98(1): 232 - 240. [Abstract] [Full Text] [PDF]

				H. U. Voss, K. Tabelow, J. Polzehl, O. Tchernichovski, K. K. Maul, D. Salgado-Commissariat, D. Ballon, and S. A. Helekar Functional MRI of the zebra finch brain during song stimulation suggests a lateralized response topography PNAS, June 19, 2007; 104(25): 10667 - 10672. [Abstract] [Full Text] [PDF]

				S. R. Crandall, N. Aoki, and T. A. Nick Developmental Modulation of the Temporal Relationship Between Brain and Behavior J Neurophysiol, January 1, 2007; 97(1): 806 - 816. [Abstract] [Full Text] [PDF]

				J. A. Mossbridge, M. B. Fitzgerald, E. S. O'Connor, and B. A. Wright Perceptual-Learning Evidence for Separate Processing of Asynchrony and Order Tasks J. Neurosci., December 6, 2006; 26(49): 12708 - 12716. [Abstract] [Full Text] [PDF]

				B. A. Carlson and M. Kawasaki Stimulus Selectivity Is Enhanced by Voltage-Dependent Conductances in Combination-Sensitive Neurons J Neurophysiol, December 1, 2006; 96(6): 3362 - 3377. [Abstract] [Full Text] [PDF]

				J. T. Sakata and M. S. Brainard Real-time contributions of auditory feedback to avian vocal motor control. J. Neurosci., September 20, 2006; 26(38): 9619 - 9628. [Abstract] [Full Text] [PDF]

				T. J. Gardner and M. O. Magnasco Sparse time-frequency representations PNAS, April 18, 2006; 103(16): 6094 - 6099. [Abstract] [Full Text] [PDF]

				M. J. Rosen and R. Mooney Synaptic Interactions Underlying Song-Selectivity in the Avian Nucleus HVC Revealed by Dual Intracellular Recordings J Neurophysiol, February 1, 2006; 95(2): 1158 - 1175. [Abstract] [Full Text] [PDF]

				C. DiMattina and X. Wang Virtual Vocalization Stimuli for Investigating Neural Representations of Species-Specific Vocalizations J Neurophysiol, February 1, 2006; 95(2): 1244 - 1262. [Abstract] [Full Text] [PDF]

				E. Akutagawa and M. Konishi Connections of thalamic modulatory centers to the vocal control system of the zebra finch PNAS, September 27, 2005; 102(39): 14086 - 14091. [Abstract] [Full Text] [PDF]

				S. M. N. Woolley and J. H. Casseday Processing of Modulated Sounds in the Zebra Finch Auditory Midbrain: Responses to Noise, Frequency Sweeps, and Sinusoidal Amplitude Modulations J Neurophysiol, August 1, 2005; 94(2): 1143 - 1157. [Abstract] [Full Text] [PDF]

				E. L. Bartlett and X. Wang Long-Lasting Modulation by Stimulus Context in Primate Auditory Cortex J Neurophysiol, July 1, 2005; 94(1): 83 - 104. [Abstract] [Full Text] [PDF]

				C. Del Negro, K. Lehongre, and J.-M. Edeline Selectivity of Canary HVC Neurons for the Bird's Own Song: Modulation by Photoperiodic Conditions J. Neurosci., May 18, 2005; 25(20): 4952 - 4963. [Abstract] [Full Text] [PDF]

				M. M. Solis and D. J. Perkel Rhythmic Activity in a Forebrain Vocal Control Nucleus In Vitro J. Neurosci., March 16, 2005; 25(11): 2811 - 2822. [Abstract] [Full Text] [PDF]

				R. Mooney and J. F. Prather The HVC Microcircuit: The Synaptic Basis for Interactions between Song Motor and Vocal Plasticity Pathways J. Neurosci., February 23, 2005; 25(8): 1952 - 1964. [Abstract] [Full Text] [PDF]

				B. A. Carlson and M. Kawasaki Nonlinear Response Properties of Combination-Sensitive Electrosensory Neurons in the Midbrain of Gymnarchus niloticus J. Neurosci., September 15, 2004; 24(37): 8039 - 8048. [Abstract] [Full Text] [PDF]

				M. J. Coleman and R. Mooney Synaptic Transformations Underlying Highly Selective Auditory Representations of Learned Birdsong J. Neurosci., August 18, 2004; 24(33): 7251 - 7265. [Abstract] [Full Text] [PDF]

				A. V. Medvedev and J. S. Kanwal Local Field Potentials and Spiking Activity in the Primary Auditory Cortex in Response to Social Calls J Neurophysiol, July 1, 2004; 92(1): 52 - 65. [Abstract] [Full Text] [PDF]

				F. E. THEUNISSEN, S. M.N. WOOLLEY, A. HSU, and T. FREMOUW Methods for the Analysis of Auditory Processing in the Brain Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 187 - 207. [Abstract] [Full Text] [PDF]

				F. E. THEUNISSEN, N. AMIN, S. S. SHAEVITZ, S. M. N. WOOLLEY, T. FREMOUW, and M. E. HAUBER Song Selectivity in the Song System and in the Auditory Forebrain Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 222 - 245. [Abstract] [Full Text] [PDF]

				C. V. MELLO, T. A.F. VELHO, and R. PINAUD Song-Induced Gene Expression: A Window on Song Auditory Processing and Perception Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 263 - 281. [Abstract] [Full Text] [PDF]

				T Q GENTNER Neural Systems for Individual Song Recognition in Adult Birds Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 282 - 302. [Abstract] [Full Text] [PDF]

				M. S. BRAINARD Contributions of the Anterior Forebrain Pathway to Vocal Plasticity Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 377 - 394. [Abstract] [Full Text] [PDF]

				M. KONISHI The Role of Auditory Feedback in Birdsong Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 463 - 475. [Abstract] [Full Text] [PDF]

				R. MOONEY Synaptic Mechanisms for Auditory-Vocal Integration and the Correction of Vocal Errors Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 476 - 494. [Abstract] [Full Text] [PDF]

				A. J. DOUPE, M. M. SOLIS, R. KIMPO, and C. A. BOETTIGER Cellular, Circuit, and Synaptic Mechanisms in Song Learning Ann. N.Y. Acad. Sci., June 1, 2004; 1016(1): 495 - 523. [Abstract] [Full Text] [PDF]

				S. M. N. Woolley and J. H. Casseday Response Properties of Single Neurons in the Zebra Finch Auditory Midbrain: Response Patterns, Frequency Coding, Intensity Coding, and Spike Latencies J Neurophysiol, January 1, 2004; 91(1): 136 - 151. [Abstract] [Full Text]

				D. Suta, E. Kvasnak, J. Popelar, and J. Syka Representation of Species-Specific Vocalizations in the Inferior Colliculus of the Guinea Pig J Neurophysiol, December 1, 2003; 90(6): 3794 - 3808. [Abstract] [Full Text] [PDF]

				J. A. Cardin and M. F. Schmidt Song System Auditory Responses Are Stable and Highly Tuned During Sedation, Rapidly Modulated and Unselective During Wakefulness, and Suppressed By Arousal J Neurophysiol, November 1, 2003; 90(5): 2884 - 2899. [Abstract] [Full Text] [PDF]

				P. J. Drew and L. F. Abbott Model of Song Selectivity and Sequence Generation in Area HVc of the Songbird J Neurophysiol, May 1, 2003; 89(5): 2697 - 2706. [Abstract] [Full Text] [PDF]

				P. A. Faure, T. Fremouw, J. H. Casseday, and E. Covey Temporal Masking Reveals Properties of Sound-Evoked Inhibition in Duration-Tuned Neurons of the Inferior Colliculus J. Neurosci., April 1, 2003; 23(7): 3052 - 3065. [Abstract] [Full Text] [PDF]

				S. C. Kadia and X. Wang Spectral Integration in A1 of Awake Primates: Neurons With Single- and Multipeaked Tuning Characteristics J Neurophysiol, March 1, 2003; 89(3): 1603 - 1622. [Abstract] [Full Text] [PDF]

				P. L. Rauske, S. D. Shea, and D. Margoliash State and Neuronal Class-Dependent Reconfiguration in the Avian Song System J Neurophysiol, March 1, 2003; 89(3): 1688 - 1701. [Abstract] [Full Text] [PDF]

				M. A. Escabi and C. E. Schreiner Nonlinear Spectrotemporal Sound Analysis by Neurons in the Auditory Midbrain J. Neurosci., May 15, 2002; 22(10): 4114 - 4131. [Abstract] [Full Text] [PDF]

				M. A. Farries and D. J. Perkel A Telencephalic Nucleus Essential for Song Learning Contains Neurons with Physiological Characteristics of Both Striatum and Globus Pallidus J. Neurosci., May 1, 2002; 22(9): 3776 - 3787. [Abstract] [Full Text] [PDF]

				M. P. Kilgard and M. M. Merzenich Order-sensitive plasticity in adult primary auditory cortex PNAS, March 5, 2002; 99(5): 3205 - 3209. [Abstract] [Full Text] [PDF]

				G. E. Hough II and S. F. Volman Short-Term and Long-Term Effects of Vocal Distortion on Song Maintenance in Zebra Finches J. Neurosci., February 1, 2002; 22(3): 1177 - 1186. [Abstract] [Full Text] [PDF]

				X. Wang and S. C. Kadia Differential Representation of Species-Specific Primate Vocalizations in the Auditory Cortices of Marmoset and Cat J Neurophysiol, November 1, 2001; 86(5): 2616 - 2620. [Abstract] [Full Text] [PDF]

				K. Sen, F. E. Theunissen, and A. J. Doupe Feature Analysis of Natural Sounds in the Songbird Auditory Forebrain J Neurophysiol, September 1, 2001; 86(3): 1445 - 1458. [Abstract] [Full Text] [PDF]

				T. Lu, L. Liang, and X. Wang Neural Representations of Temporally Asymmetric Stimuli in the Auditory Cortex of Awake Primates J Neurophysiol, June 1, 2001; 85(6): 2364 - 2380. [Abstract] [Full Text] [PDF]

				G. L. Miller and E. I. Knudsen Early Auditory Experience Induces Frequency-Specific, Adaptive Plasticity in the Forebrain Gaze Fields of the Barn Owl J Neurophysiol, May 1, 2001; 85(5): 2184 - 2194. [Abstract] [Full Text] [PDF]

				A. S. Dave and D. Margoliash Song Replay During Sleep and Computational Rules for Sensorimotor Vocal Learning Science, October 27, 2000; 290(5492): 812 - 816. [Abstract] [Full Text]

				M. M. Solis, M. S. Brainard, N. A. Hessler, and A. J. Doupe Song selectivity and sensorimotor signals in vocal learning and production PNAS, October 24, 2000; 97(22): 11836 - 11842. [Abstract] [Full Text] [PDF]

				T. W. Troyer and A. J. Doupe An Associational Model of Birdsong Sensorimotor Learning II. Temporal Hierarchies and the Learning of Song Sequence J Neurophysiol, September 1, 2000; 84(3): 1224 - 1239. [Abstract] [Full Text] [PDF]

				S. Ribeiro and C.V. Mello Gene Expression and Synaptic Plasticity in the Auditory Forebrain of Songbirds Learn. Mem., September 1, 2000; 7(5): 235 - 243. [Full Text]

				R. Mooney Different Subthreshold Mechanisms Underlie Song Selectivity in Identified HVc Neurons of the Zebra Finch J. Neurosci., July 15, 2000; 20(14): 5420 - 5436. [Abstract] [Full Text] [PDF]

				M. J. Rosen and R. Mooney Intrinsic and Extrinsic Contributions to Auditory Selectivity in a Song Nucleus Critical for Vocal Plasticity J. Neurosci., July 15, 2000; 20(14): 5437 - 5448. [Abstract] [Full Text] [PDF]

				P. Marler and A. J. Doupe Singing in the brain PNAS, March 28, 2000; 97(7): 2965 - 2967. [Full Text] [PDF]

				F. E. Theunissen, K. Sen, and A. J. Doupe Spectral-Temporal Receptive Fields of Nonlinear Auditory Neurons Obtained Using Natural Sounds J. Neurosci., March 15, 2000; 20(6): 2315 - 2331. [Abstract] [Full Text] [PDF]

				D. V. Buonomano Decoding Temporal Information: A Model Based on Short-Term Synaptic Plasticity J. Neurosci., February 1, 2000; 20(3): 1129 - 1141. [Abstract] [Full Text] [PDF]

				J. I. Gold and E. I. Knudsen Abnormal Auditory Experience Induces Frequency-Specific Adjustments in Unit Tuning for Binaural Localization Cues in the Optic Tectum of Juvenile Owls J. Neurosci., January 15, 2000; 20(2): 862 - 877. [Abstract] [Full Text] [PDF]

				A. V. Galazyuk, D. Llano, and A. S. Feng Temporal Dynamics of Acoustic Stimuli Enhance Amplitude Tuning of Inferior Colliculus Neurons J Neurophysiol, January 1, 2000; 83(1): 128 - 138. [Abstract] [Full Text] [PDF]

				N. A. Hessler and A. J. Doupe Singing-Related Neural Activity in a Dorsal Forebrain-Basal Ganglia Circuit of Adult Zebra Finches J. Neurosci., December 1, 1999; 19(23): 10461 - 10481. [Abstract] [Full Text] [PDF]

				P. Janata and D. Margoliash Gradual Emergence of Song Selectivity in Sensorimotor Structures of the Male Zebra Finch Song System J. Neurosci., June 15, 1999; 19(12): 5108 - 5118. [Abstract] [Full Text] [PDF]

				M. M. Solis and A. J. Doupe Contributions of Tutor and Bird's Own Song Experience to Neural Selectivity in the Songbird Anterior Forebrain J. Neurosci., June 1, 1999; 19(11): 4559 - 4584. [Abstract] [Full Text] [PDF]

				H. Sakaguchi, K. Wada, M. Maekawa, T. Watsuji, and M. Hagiwara Song-Induced Phosphorylation of cAMP Response Element-Binding Protein in the Songbird Brain J. Neurosci., May 15, 1999; 19(10): 3973 - 3981. [Abstract] [Full Text] [PDF]

				G. L. Miller and E. I. Knudsen Early Visual Experience Shapes the Representation of Auditory Space in the Forebrain Gaze Fields of the Barn Owl J. Neurosci., March 15, 1999; 19(6): 2326 - 2336. [Abstract] [Full Text] [PDF]

				A. S. Dave, A. C. Yu, and D. Margoliash Behavioral State Modulation of Auditory Activity in a Vocal Motor System Science, December 18, 1998; 282(5397): 2250 - 2254. [Abstract] [Full Text]