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Journal of Neuroscience, Vol 5, 1062-1075, Copyright © 1985 by Society for Neuroscience
Studies of the earliest generated cells of the cat's visual cortex: cogeneration of subplate and marginal zones
MB Luskin and CJ Shatz
The earliest generated cells of the cat's telencephalon that may play a
role in the formation of the primary visual cortex are the subject of this
study. Using [3H]thymidine autoradiography, we have found that these cells
are generated between embryonic day 24 (E24) and E30 (gestation is 65 days)
and that they are present in very low numbers in the white matter of the
adult brain. These cells are rarely labeled by injections made after E30,
when the cells destined for the cortical layers are generated. Examination
of the labeling pattern in the fetal brain 10 days or more after
administration of [3H]thymidine between E24 and E30 revealed a bistratified
distribution of these early generated cells. Labeled cells were found in
large numbers in two embryonic zones flanking the developing cortical
plate: above in the marginal zone and below in the subplate. (Some if not
all of the marginal zone cells constitute the population of Cajal-Retzius
cells of the cat's telencephalon.). These experiments indicate that cells
of the subplate and marginal zones are cogenerated in time during the days
just preceding the genesis of the cortical plate. We also examined the
distribution of the early generated cells shortly after their genesis-- on
E30, a time when cells of the cortical plate are just being generated at
the ventricular zone. In this case, the labeling pattern at the occipital
pole was not bistratified. Rather, labeled cells were situated within a
single zone extending from the pial surface inward to the border of the
ventricular zone. This finding indicates that the cells of the subplate and
marginal zones are generated as a contiguous population that is
subsequently split apart by the insertion of cells forming the cortical
plate. A comparison between the number of early generated cells found in
fetal and newborn brains with that found in adult brains suggests that
these cells are generated initially in substantial numbers but then largely
disappear during early postnatal life, since injections of [3H]thymidine
between E24 and E30 yielded large numbers of labeled cells in the white
matter and layer 1 at birth, but very few at 2 months postnatal. This
significant loss contrasted with the results from injections made just a
few days later (E33) that resulted in large numbers of labeled cells in
cortical layer 6 not only at birth but also in adulthood.(ABSTRACT
TRUNCATED AT 400 WORDS)
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|
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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B. Finlay and R. Darlington
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268(5217):
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[PDF]
|
|
|
|
|
|
|
D. Emerling and A. Lander
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120(10):
2811 - 2822.
[Abstract]
[PDF]
|
|
|
|
|
|
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A Ghosh and C. Shatz
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January 3, 1993;
117(3):
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[PDF]
|
|
|
|
|
|
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R. Mullen, C. Buck, and A. Smith
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January 9, 1992;
116(1):
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[Abstract]
[PDF]
|
|
|
|
|
|
|
S. McConnell, A Ghosh, and C. Shatz
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September 1, 1989;
245(4921):
978 - 982.
[Abstract]
[PDF]
|
|
|
|
|
|
|
P Rakic
Specification of cerebral cortical areas
Science,
July 8, 1988;
241(4862):
170 - 176.
[Abstract]
[PDF]
|
|
|
|
