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Next Article 
Journal of Neuroscience, Vol 6, 1-13, Copyright © 1986 by Society for Neuroscience
A functional organization of ON and OFF pathways in the rabbit retina
SA Bloomfield and RF Miller
Intracellular electrophysiological recordings were obtained from amacrine
and ganglion cells in an isolated, superfused retina-eyecup preparation of
the rabbit. Cells were characterized physiologically, after which
cell-staining was accomplished by intracellular iontophoresis of HRP. A
computer-assisted image-processing system was used to study the dendritic
stratification pattern of HRP-labeled neurons within the inner plexiform
layer (IPL). Our results support the concept that the IPL is functionally
divided into a distal OFF region and proximal ON layer. ON and OFF ganglion
and amacrine cells show dendritic arborizations consistent with this
division and ON-OFF ganglion cells have processes in both portions of the
IPL. It appears that these functional subdivisions of the IPL reflect
excitatory, but not necessarily inhibitory, inputs. Thus, the pattern of
dendritic arborization of a cell appears to predict its physiological
response polarity, regardless of the type of inhibition it receives.
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H.-A. Hsueh, A. Molnar, and F. S. Werblin
Amacrine-to-Amacrine Cell Inhibition in the Rabbit Retina
J Neurophysiol,
October 1, 2008;
100(4):
2077 - 2088.
[Abstract]
[Full Text]
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J. Petit-Jacques and S. A. Bloomfield
Synaptic Regulation of the Light-Dependent Oscillatory Currents in Starburst Amacrine Cells of the Mouse Retina
J Neurophysiol,
August 1, 2008;
100(2):
993 - 1006.
[Abstract]
[Full Text]
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J. M. Ackert, S. H. Wu, J. C. Lee, J. Abrams, E. H. Hu, I. Perlman, and S. A. Bloomfield
Light-induced changes in spike synchronization between coupled ON direction selective ganglion cells in the mammalian retina.
J. Neurosci.,
April 19, 2006;
26(16):
4206 - 4215.
[Abstract]
[Full Text]
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J. Petit-Jacques, B. Volgyi, B. Rudy, and S. Bloomfield
Spontaneous Oscillatory Activity of Starburst Amacrine Cells in the Mouse Retina
J Neurophysiol,
September 1, 2005;
94(3):
1770 - 1780.
[Abstract]
[Full Text]
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A. Ozaita, J. Petit-Jacques, B. Volgyi, C. S. Ho, R. H. Joho, S. A. Bloomfield, and B. Rudy
A Unique Role for Kv3 Voltage-Gated Potassium Channels in Starburst Amacrine Cell Signaling in Mouse Retina
J. Neurosci.,
August 18, 2004;
24(33):
7335 - 7343.
[Abstract]
[Full Text]
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E. H. Hu and S. A. Bloomfield
Gap Junctional Coupling Underlies the Short-Latency Spike Synchrony of Retinal {alpha} Ganglion Cells
J. Neurosci.,
July 30, 2003;
23(17):
6768 - 6777.
[Abstract]
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J.-J. Pang, F. Gao, and S. M. Wu
Light-Evoked Excitatory and Inhibitory Synaptic Inputs to ON and OFF {alpha} Ganglion Cells in the Mouse Retina
J. Neurosci.,
July 9, 2003;
23(14):
6063 - 6073.
[Abstract]
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E. Gunhan-Agar, D. Kahn, and L. M. Chalupa
Segregation of On and Off Bipolar Cell Axonal Arbors in the Absence of Retinal Ganglion Cells
J. Neurosci.,
January 1, 2000;
20(1):
306 - 314.
[Abstract]
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G. Chechik, I. Meilijson, and E. Ruppin
Neuronal Regulation: A Mechanism for Synaptic Pruning During Brain Maturation
Neural Comput.,
November 15, 1999;
11(8):
2061 - 2080.
[Abstract]
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E. S. Simon
Involvement of glycine and GABAA receptors in the pathogenesis of spinal myoclonus: In vitro studies in the isolated neonatal rodent spinal cord
Neurology,
October 1, 1995;
45(10):
1883 - 1892.
[Abstract]
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