 |
||||
|
||||
|
||||
|
||||
Journal of Neuroscience, Vol 7, 1595-1600, Copyright © 1987 by Society for Neuroscience
ARTICLE
Interactions between growth cones and neurites growing from different neural tissues in culture
JP Kapfhammer and JA Raper
We have previously used retinal and sympathetic explants to show that growth cones recognize and retract from specific neurites in culture (Kapfhammer et al., 1986). In an effort to determine the generality of this phenomenon and to see how many different neurite labels can be detected by it, we have studied interactions between individual growth cones and neurites extending from a variety of neural sources in vitro. Using most of the possible pairings between sympathetic, ciliary, dorsal root ganglion (DRG), retinal, and diencephalic neurons, we have found that in most instances: (1) Growth cones do not retract from neurites originating from the same tissue; (2) retinal growth cones do not retract from diencephalic neurites; (3) sympathetic, ciliary, and DRG growth cones, with one possible exception, do not retract from sympathetic, ciliary, or DRG neurites; (4) retinal growth cones retract from sympathetic, ciliary, and DRG neurites; (5) sympathetic, ciliary, and DRG growth cones retract from retinal neurites; and (6) sympathetic growth cones retract from diencephalic neurites. A simple hypothesis consistent with these results is that 2 labels exist--one associated with central neurites and another associated with peripheral neurites-- and that peripheral growth cones are programmed to retract from the central label and central growth cones are programmed to retract from sympathetic, ciliary, and DRG neurites; (5) symevant to the separation of the CNS and PNS during development.
This article has been cited by other articles:
D. Bagnard, N. Chounlamountri, A. W. Puschel, and J. Bolz
Axonal Surface Molecules Act in Combination with Semaphorin 3A during the Establishment of Corticothalamic Projections
Cereb Cortex, March 1, 2001; 11(3): 278 - 285.
[Abstract] [Full Text] [PDF]
X.-M. Xu, D. A. Fisher, L. Zhou, F. A. White, S. Ng, W. D. Snider, and Y. Luo
The Transmembrane Protein Semaphorin 6A Repels Embryonic Sympathetic Axons
J. Neurosci., April 1, 2000; 20(7): 2638 - 2648.
[Abstract] [Full Text] [PDF]
J. C. Glover
Development of Specific Connectivity Between Premotor Neurons and Motoneurons in the Brain Stem and Spinal Cord
Physiol Rev, April 1, 2000; 80(2): 615 - 647.
[Abstract] [Full Text] [PDF]
B. A. de la Houssaye, K. Mikule, D. Nikolic, and K. H. Pfenninger
Thrombin-Induced Growth Cone Collapse: Involvement of Phospholipase A2 and Eicosanoid Generation
J. Neurosci., December 15, 1999; 19(24): 10843 - 10855.
[Abstract] [Full Text] [PDF]
D Bagnard, M Lohrum, D Uziel, A. Puschel, and J Bolz
Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections
Development, January 12, 1998; 125(24): 5043 - 5053.
[Abstract] [PDF]
I. Shepherd, Y Luo, F Lefcort, L. Reichardt, and J. Raper
A sensory axon repellent secreted from ventral spinal cord explants is neutralized by antibodies raised against collapsin-1
Development, January 4, 1997; 124(7): 1377 - 1385.
[Abstract] [PDF]
R Tuttle and W. Matthew
Neurotrophins affect the pattern of DRG neurite growth in a bioassay that presents a choice of CNS and PNS substrates
Development, January 5, 1995; 121(5): 1301 - 1309.
[Abstract] [PDF]
M. E. Selzer
Mechanisms of Functional Recovery in Traumatic Brain Injury
Neurorehabil Neural Repair, January 1, 1995; 9(2): 73 - 82.
[PDF]
J Dodd and T. Jessell
Axon guidance and the patterning of neuronal projections in vertebrates
Science, November 4, 1988; 242(4879): 692 - 699.
[Abstract] [PDF]
|
|
|
|
 |
|