 |
 Previous Article | Next Article 
Journal of Neuroscience, Vol 8, 3757-3769, Copyright © 1988 by Society for Neuroscience
Effects of lesions of temporal-parietal junction on perceptual and attentional processing in humans
LC Robertson, MR Lamb and RT Knight
Department of Psychiatry, University of California, Davis.
When stimuli with larger forms (global) containing smaller forms (local)
are presented to subjects with large lesions in the right hemisphere, they
are more likely to miss the global form than the local form, whereas
subjects with large lesions in the left are more likely to miss the local
than the global form. The present study tested whether the global/local
impairment in subjects with posterior lesions was due to deficits in
controlled attentional processes, passive perceptual processes, or both.
Attentional control was examined by measuring reaction time changes when
the probability of a target appearing at either the global or local level
was varied. Patients with unilateral right or left lesions centered in
temporal-parietal regions and age-matched controls served as subjects.
Because neurophysiological and neuropsychological evidence have implicated
temporal regions in visual discrimination and inferior parietal regions in
the allocation of attention to locations in the visual field, patients with
left hemisphere lesions were further subdivided into those with lesions
centered in the superior temporal gyrus (LSTG) or rostral inferior parietal
lobule (LIPL). Patients with right hemisphere injury could not be
analogously subdivided. The results revealed that the LSTG group was able
to control the allocation of attention to global and local levels normally,
while the LIPL group was not. In contrast, the LSTG group showed a strong
baseline reaction time advantage toward global targets, while normals and
the LIPL group showed no advantage toward one level or the other. Finally,
the perceptual component was affected differentially by lesions in the
right hemisphere and LSTG, with lesions in the left favoring global targets
and lesions in the right favoring local targets. These findings indicate
that the hemispheric global/local asymmetry is due to a perceptual
mechanism with a critical anatomical locus centered in the STG.
This article has been cited by other articles:
|
|
|
|
 
Q. Chen, J. C. Marshall, R. Weidner, and G. R. Fink
Zooming In and Zooming Out of the Attentional Focus: An fMRI Study
Cereb Cortex,
August 9, 2008;
(2008)
bhn128v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Gronau, M. Neta, and M. Bar
Integrated contextual representation for objects' identities and their locations.
J. Cogn. Neurosci.,
March 1, 2008;
20(3):
371 - 388.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Cicek, D. Gitelman, R. S. E. Hurley, A. Nobre, and M. Mesulam
Anatomical Physiology of Spatial Extinction
Cereb Cortex,
December 1, 2007;
17(12):
2892 - 2898.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. W. Nordahl, D. Dierker, I. Mostafavi, C. M. Schumann, S. M. Rivera, D. G. Amaral, and D. C. Van Essen
Cortical Folding Abnormalities in Autism Revealed by Surface-Based Morphometry
J. Neurosci.,
October 24, 2007;
27(43):
11725 - 11735.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Rotshtein, J. J. Geng, J. Driver, and R. J. Dolan
Role of Features and Second-order Spatial Relations in Face Discrimination, Face Recognition, and Individual Face Skills: Behavioral and Functional Magnetic Resonance Imaging Data.
J. Cogn. Neurosci.,
September 1, 2007;
19(9):
1435 - 1452.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Rose, T. Sommer, and C. Buchel
Integration of Local Features to a Global Percept by Neural Coupling
Cereb Cortex,
October 1, 2006;
16(10):
1522 - 1528.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D.H. Weissman and M.G. Woldorff
Hemispheric Asymmetries for Different Components of Global/Local Attention Occur in Distinct Temporo-parietal Loci
Cereb Cortex,
June 1, 2005;
15(6):
870 - 876.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. K. Mannan, D. J. Mort, T. L. Hodgson, J. Driver, C. Kennard, and M. Husain
Revisiting Previously Searched Locations in Visual Neglect: Role of Right Parietal and Frontal Lesions in Misjudging Old Locations as New
J. Cogn. Neurosci.,
February 1, 2005;
17(2):
340 - 354.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Pavlova, W. Lutzenberger, A. Sokolov, and N. Birbaumer
Dissociable Cortical Processing of Recognizable and Non-recognizable Biological Movement: Analysing Gamma MEG Activity
Cereb Cortex,
February 1, 2004;
14(2):
181 - 188.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A Parton, P Malhotra, and M Husain
Hemispatial neglect
J. Neurol. Neurosurg. Psychiatry,
January 1, 2004;
75(1):
13 - 21.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. W. Schrimsher, R. L. Billingsley, E. F. Jackson, and B. D. Moore
Caudate Nucleus Volume Asymmetry Predicts Attention-Deficit Hyperactivity Disorder (ADHD) Symptomatology in Children
J Child Neurol,
December 1, 2002;
17(12):
877 - 884.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. M. Murray, G. R. Wylie, B. A. Higgins, D. C. Javitt, C. E. Schroeder, and J. J. Foxe
The Spatiotemporal Dynamics of Illusory Contour Processing: Combined High-Density Electrical Mapping, Source Analysis, and Functional Magnetic Resonance Imaging
J. Neurosci.,
June 15, 2002;
22(12):
5055 - 5073.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. Simmers and P. J. Bex
Deficit of Visual Contour Integration in Dyslexia
Invest. Ophthalmol. Vis. Sci.,
October 1, 2001;
42(11):
2737 - 2742.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A.-J. Wegner, A. Gunthner, and M. Fahle
Visual performance and recovery in recently detoxified alcoholics
Alcohol Alcohol.,
March 1, 2001;
36(2):
171 - 179.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Sasaki, N. Hadjikhani, B. Fischl, A. K. Liu, S. Marrett, A. M. Dale, and R. B. H. Tootell
Local and global attention are mapped retinotopically in human occipital cortex
PNAS,
February 13, 2001;
98(4):
2077 - 2082.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. J. Perry and S. Zeki
The neurology of saccades and covert shifts in spatial attention: An event-related fMRI study
Brain,
November 1, 2000;
123(11):
2273 - 2288.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Driver and A. Pouget
Object-Centered Visual Neglect, or Relative Egocentric Neglect?
J. Cogn. Neurosci.,
May 1, 2000;
12(3):
542 - 545.
[Full Text]
|
|
|
|
|
|
|
G. R. Fink, J. C. Marshall, P. W. Halligan, and R. J. Dolan
Neuronal Activity in Early Visual Areas during Global and Local Processing: A Comment on Heinze, Hinrichs, Scholz, Burchert, and Mangun
J. Cogn. Neurosci.,
March 1, 2000;
12(2):
355 - 356.
[Full Text]
|
|
|
|
|
|
|
B. S. Oken, S. S. Kishiyama, J. A. Kaye, and D. E. Jones
Age-Related Differences in Global- Local Processing: Stability of Laterality Differences but Disproportionate Impairment in Global Processing
J Geriatr Psychiatry Neurol,
July 1, 1999;
12(2):
76 - 81.
[Abstract]
[PDF]
|
|
|
|
|
|
|
S. Yamaguchi, S. Yamagata, and S. Kobayashi
Cerebral Asymmetry of the "Top-Down" Allocation of Attention to Global and Local Features
J. Neurosci.,
May 1, 2000;
20(9):
RC72 - RC72.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
