QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Boulis, N. M. Articles by Sahley, C. L. Search for Related Content PubMed PubMed Citation Articles by Boulis, N. M. Articles by Sahley, C. L.

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 8, 4621-4627, Copyright © 1988 by Society for Neuroscience

ARTICLE

A behavioral analysis of habituation and sensitization of shortening in the semi-intact leech

NM Boulis and CL Sahley
Department of Biology, Yale University, New Haven, Connecticut 06511.

We have previously demonstrated that the shortening reflex of the leech Hirudo medicinalis displays habituation, dishabituation, and sensitization. In this paper we demonstrate that the shortening reflex of the semi-intact animal also displays these phenomena. In the first experiment we found that the magnitude of the touch-elicited shortening reflex decreased as a result of repeated stimulations of the skin every 2 min. The second experiment examined the change in this reflex as a function of the interstimulus interval (ISI). The reflex failed to decrease when the ISI was 10 sec, but decreased significantly when the ISI was either 45 or 360 sec. Finally, in a third experiment we found that the presentation of noxious stimuli prior to habituation training prevented habituation. Thus, as we have observed previously in the intact animal, the semi-intact animal displays habituation, dishabituation, and sensitization.

This article has been cited by other articles:

				B. G. Schreurs Classical Conditioning and Modification of the Rabbit's (Oryctolagus Cuniculus) Unconditioned Nictitating Membrane Response Behav Cogn Neurosci Rev, June 1, 2003; 2(2): 83 - 96. [Abstract] [PDF]

				J. E. Engel, X.-J. Xie, M. B. Sokolowski, and C.-F. Wu A cGMP-Dependent Protein Kinase Gene, foraging, Modifies Habituation-Like Response Decrement of the Giant Fiber Escape Circuit in Drosophila Learn. Mem., September 1, 2000; 7(5): 341 - 352. [Abstract] [Full Text]

				S. A. Baccus, B. D. Burrell, C. L. Sahley, and K. J. Muller Action Potential Reflection and Failure at Axon Branch Points Cause Stepwise Changes in EPSPs in a Neuron Essential for Learning J Neurophysiol, March 1, 2000; 83(3): 1693 - 1700. [Abstract] [Full Text] [PDF]

				B. D. Burrell and C. L. Sahley Generalization of Habituation and Intrinsic Sensitization in the Leech Learn. Mem., November 1, 1998; 5(6): 405 - 419. [Abstract] [Full Text]

				J. E. Engel and C.-F. Wu Genetic Dissection of Functional Contributions of Specific Potassium Channel Subunits in Habituation of an Escape Circuit in Drosophila J. Neurosci., March 15, 1998; 18(6): 2254 - 2267. [Abstract] [Full Text] [PDF]

				B. K. Modney, C. L. Sahley, and K. J. Muller Regeneration of a Central Synapse Restores Nonassociative Learning J. Neurosci., August 15, 1997; 17(16): 6478 - 6482. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help