QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

HOME  |   SEARCH  |   ARCHIVE  |   SUBSCRIBE  |   CONTACT  |   HELP

This Article Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Maioli, C. Search for Related Content PubMed PubMed Citation Articles by Maioli, C.

 Previous Article  |  Next Article 

Journal of Neuroscience, Vol 8, 821-832, Copyright © 1988 by Society for Neuroscience

ARTICLE

Optokinetic nystagmus: modeling the velocity storage mechanism

C Maioli
Istituto di Fisiologia dei Centri Nervosi-C.N.R., Milano, Italy.

To account for the oscillatory behavior of the optokinetic after- nystagmus (OKAN), a nonlinear model of the optokinetic system is proposed here that includes 2 first-order storage elements interconnected in a negative feedback loop. The adequacy of the model is tested by comparing its predictions with experimental data available in the literature. In addition, the question of the contribution of the storage element responsible for secondary OKAN (OKAN II) to the dynamic properties of the optokinetic nystagmus (OKN) is addressed. The results show that the model is compatible with all modifications of the OKAN time course observed under various experimental situations. By comparing computer simulations and experimental data, it is inferred that (1) the dynamic properties of the optokinetic system during OKN and during OKAN are different; (2) the switching in velocity storage dynamics is not determined by the light-dark transition, but is induced whenever nystagmic slow phase velocity (SPV) is not sustained by an appropriate retinal slip error signal; (3) although no signs of adaptation are seen during OKN, the storage element responsible for OKAN II becomes charged during optokinetic stimulation; and (4) the time constants of the integrators are affected by the parameters of the preceding optokinetic stimulation.

This article has been cited by other articles:

				V. E. Pettorossi, P. Errico, A. Ferraresi, and N. H. Barmack Optokinetic and Vestibular Stimulation Determines the Spatial Orientation of Negative Optokinetic Afternystagmus in the Rabbit J. Neurosci., February 15, 1999; 19(4): 1524 - 1531. [Abstract] [Full Text] [PDF]

Home  |   Search  |   Archive  |   Subscribe  |   Contact  |   Help