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Figure 6. The middle degeneration stage. A, The PVM nucleus (labeled with the cell name) is highly indented, invaded by a cytoplasmic vacuole (vac), and its chromatin is condensed. Several very large whorls of membrane cause cell swelling. The cytoplasm is slightly less electron-dense than that of nearby tissues. B, A different section of the same cell as in A, showing the mild swelling of the Golgi apparatus (G). C, A degenerating AVM cell has a huge vacuole (vac) invading the nucleus (labeled with the cell name), which is pushed to the edge of the soma. Cytoplasm of AVM is lighter than that of surrounding tissues. D, PVC soma in a late L1 stage (12 hr after hatching) deg-1(u38) larva is filled with large and small membrane whorls and vacuoles. The nucleus (not shown) was distorted in shape but otherwise normal in appearance. Magnification is the same in A-C.



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