The Journal of Neuroscience, August 1, 2002, 22(15):6835-6835
ERRATUM
In the article "Dopamine Modulates
Excitability of Spiny Neurons in the Avian Basal Ganglia," by Long
Ding and David J. Perkel, which appeared on pages 5210-5218 of the
June 15, 2002 issue, Figures 5 and 10 were
inadvertently switched, although the legends are correct as shown. The
correct version of each figure, as well as its legend, is printed in
this issue.
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Figure 5.
The D1-like DA receptor antagonist
SCH-23390 blocked the excitatory effect of SKF-38393 and DA. All data
were collected from the same spiny neuron. A, SKF-38393
(10 µM) enhanced excitability. B,
SCH-23390 (20 µM) blocked the effect of SKF-38393 (10 µM). C, DA (50 µM) enhanced excitability.
D, In the presence of SCH-23390 (20 µM),
DA (50 µM) reduced evoked firing.
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Figure 10.
The slope of the initial ramp is
modulated by quinpirole, SKF-38393, and TTX. A, The
percentage change in the slope of the initial ramp as a function of the
percentage change in evoked firing induced by quinpirole
(n = 15) (median value,  28.6%; the slope was not
measured in one cell held at 62 mV, which fired action potentials
with very short latency). Solid line, Linear regression,
r2 = 0.738; dotted
line, 95% confidence interval of the regression line.
Horizontal dashed line indicates 0%. Data
points in shaded box were obtained in the
presence of 1 µM TTX (n = 7; median
value 12.5%). B, The percentage change in the slope
of the initial ramp as a function of the percentage change in evoked
firing induced by SKF-38393 (n = 14; median value
3.3%). Solid line, Linear regression,
r2 = 0.531; dotted
line, 95% confidence interval of the regression line. Note:
the rightmost data point was included for all analyses except the
linear regression. Horizontal dashed line indicates 0%.
Data points in shaded box were obtained
in the presence of 1 µM TTX (n = 5;
median value 1.0%). C, Example traces from a spiny
neuron. The baseline voltage response (thin line) had a
steeper ramp before action potential and an earlier onset of the
first spike, compared with the response in the presence of quinpirole
(thick line). Membrane potential: 65 mV.
D, TTX reduced the slope of the ramp but did not block
the quinpirole-induced decrease. Example traces from another spiny
neuron. Quinpirole (10 µM) was applied in the presence of
1 µM TTX. Membrane potential: 88 mV. The control trace
(PRE) is shifted by 1.9 mV to facilitate comparison.
The TTX and QUIN traces shown are
averages of three traces each.
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