The Journal of Neuroscience, August 20, 2003, ():
Developmental Modulation of Retinal Wave Dynamics: Shedding Light on the GABA Saga
J. Neurosci.
Sernagor et al. 23 (20): 7621.
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Files in this Data Supplement:
- Supplementary Movie 1
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Spontaneous wave of activity in the RGC layer in a S23 retina. Cells were back-labeled with CGD. The background fluorescence has been subtracted from the images, so that only increases in fluorescence, associated with Ca2+ and electrical activity are visible (played back in real time). The wave is fast and widespreading.
- Supplementary Movie 2
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Spontaneous wave of activity in the RGC layer in a S25 retina. The wave is much slower and more winding than at S23.
- Supplementary Movie 3
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GABA-induced wave of activity in the RGC layer in a S25 retina. Here the activity is not spontaneous, but rather induced by a puff of GABA (50 µM) in the chamber. The activity is played back 4 times faster than real time.
- Supplementary Movie 4
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Spontaneous activity in the RGC layer in a DR4 retina. The activity exhibits both patches and propagation. In normal rearing conditions, there is no correlated spontaneous activity anymore at this stage.
