The Journal of Neuroscience, May 1, 2003, ():
The Basement Membrane Components Nidogen and Type XVIII Collagen Regulate Organization of Neuromuscular Junctions in Caenorhabditis elegans
J. Neurosci.
Ackley et al. 23 (9): 3577.
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Files in this Data Supplement:
- Movie 1
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Video of cle-1(cg120) animal in thrashing assay. The animal’s head is to the left and ventral is down. These mutants display a reduced frequency of thrashing and the movements are often uncoordinated. The animal first moves the tail and then the head, rather than the coordinated movement observed in wild-type animals. These mutants also occasionally display an over-bending behavior, in which the head crosses the tail.
- Movie 2
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Video of nid-1(cg119) animal in thrashing assay. At the beginning of the movie the animal’s head is to the left and is pointing up. The nidogen null mutant displays a frequent over-bending behavior, in which the animal’s head crosses over the tail. This behavior is only very infrequently observed in wild-type animals.
- Movie 3
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Video of nid-1(cg118) animal in thrashing assay. The animals head is to the left and ventral is down. The nidogen DG2 mutants frequently display a reduced amplitude of bending, leading to a shorter distance traveled during the movement. These mutants also occasionally over-bend, as seen frequently in the nidogen null mutants.
- Movie 4
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Video of wild-type, N2, animal in thrashing assay. In this movie the animals head is to the left and ventral is up. The animals flex about the midbody, bringing the head and tail towards each other. The frequency and amplitude of the movement appear consistent throughout the behavior.
