The Journal of Neuroscience, August 4, 2004, ():
Striatal Neuron Differentiation from Neurosphere-Expanded Progenitors Depends on Gsh2 Expression
J. Neurosci. Jensen et al.
24: 6958
Supplemental data
Files in this Data Supplement:
- supplemental Fig. 1
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Supplemental Figure 1. Effects of BDNF and RA during in vitro differentiation of neurosphere-expanded cells. A, C--F, LGE-derived neurospheres differentiated in the presence of BDNF and/or RA showed the same neurogenic potential, but an increased number of GABAergic neurons were formed in the presence of BDNF and RA (B, G--J). Error bars indicate SEM. *p [lt] 0.05. Scale bars, 50 m.
- supplemental Fig. 2
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Supplemental Figure 2. Lack of striatal neuron differentiation in cells expanded as attached monolayer cultures. A, D, LGE-derived cells expanded in attached monolayer cultures were detected in the cocultures by the transgenic expression of -gal. B, C, Many -gal+ cells coexpressed -III-tubulin, however, only the primary LGE cells expressed ISL1, because ISL1 was never found to be coexpressed with -gal (E, F). Scale bars, 50 m.
