The Journal of Neuroscience, March 3, 2004, ():
Corticospinal System Development Depends on Motor Experience
J. Neurosci. Martin et al.
24: 2122
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Files in this Data Supplement:
- Supplementary video
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This video shows the end of the reach, the grasp, and food withdrawal during prehension in the cat. Initially 2 sample movements made by the non-injected limb (control; see Methods) are shown. This is followed by 3 movements made by the BTX-injected limb, which was prevented from moving during early postnatal development. For the non-injected limb, the paw enters the tube accurately, lands on the food morsel, grasps and withdraws. During withdrawal there is forearm supination. Compare the pronated position of the paw just after it contacts the food (i.e., horizontal) with the supinated position of the paw as it withdraws the food (i.e., vertical). The food is scooped into the paw. For the limb that received BTX injections, all three responses show that the paw enters the tube accurately, contacts and grasps the food, just like the non-injected limb. The principal difference is that the food is dragged out of the tube without corresponding forearm supination. Compare the protracted position of the paw just after it contacts the food with the same protracted position as it withdraws the food. The food is quickly raked out of the tube. As the food is raked from the tube, it drops out of the paw.
