The Journal of Neuroscience, May 4, 2005, ():
Spontaneous Recovery from Extinction Depends on the Reconsolidation of the Acquisition Memory in an Appetitive Learning Paradigm in the Honeybee (Apis mellifera)
J. Neurosci. Stollhoff et al.
25: 4485
Supplemental data
Files in this Data Supplement:
- supplemental material
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Figure 1-1. In an appetitive olfactory learning paradigm, one CS-only trial presented after memory is consolidated did not lead to extinction.
On day 1 all animals were subjected to three CS-US pairings (A1-A3) with an inter-trial interval (ITI) of 10 min (= acquisition). After 24 h, on day 2, one CS-only (C1) trial was presented. At each time point after the CS-only trial a subgroup of animals was tested with one CS-only trial (= test) (A)-(E) Subgroups of all tested time points. (A): 1 h after CS-only trial, (B): 2 h after the CS-only trial, (C): 4 h after the CS-only trial, (D): 24 h after the CS-only trial, (E): 48 h after the CS-only trial. % CR: Percentage of animals that show a proboscis extension response during CS presentation; black circles and bars: retrieved group; grey circles and bars: non-retrieved group. The number of animals tested in the different groups is indicated in parentheses.
- supplemental material
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Figure 2-1. In an appetitive olfactory learning paradigm, two CS-only trials presented after memory is consolidated lead to extinction. On day 1 all animals were subjected to three CS-US pairings (A1-A3) with an ITI of 10 min (= acquisition). After 24 h, on day 2, two CS-only (C1, C2) trials were presented with an ITI of 10 min. At each time point after the last CS-only trial a subgroup of animals was tested with one CS-only trial (= test).
(A)-(E) Subgroups of all tested time points: (A): 1 h after two CS-only trials, (B): 2 h after two CS-only trials, (C): 4 h after two CS-only trials, (D): 24 h after two CS-only trials, (E): 48 h after two CS-only trials. Asterisks indicate significant differences (p < 0.05) in the CRs between retrieved and non-retrieved animals, or a significant difference in the CRs of the retrieved group between the last CS-only trial and the retention test; % CR: Percentage of animals that show a proboscis extension response during CS presentation, black circles and bars = retrieved group; grey circles and bars = non-retrieved group. The number of animals tested in the different groups is indicated in parentheses.
- supplemental material
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Figure 3-1. In an appetitive olfactory learning paradigm, five CS-only trials presented after memory is consolidated lead to extinction and spontaneous recovery. On day 1 all animals were subjected to three CS-US pairings (A1-A3) with an ITI of 10 min (= acquisition). After 24 h, on day 2, five CS-only trials (C1-C5) were presented with an ITI of 10 min. At each time point after the last CS-only trial a subgroup of animals was tested with one CS-only trial (= test).
(A)-(E) Subgroups of all tested time points: (A): 1 h after five CS-only trials, (B): 2h after five CS-only trials, (C): 4h after five CS-only trials, (D) 24 h after five CS-only trials, (E) 48 h after five CS-only trials. Asterisks indicate significant differences (p < 0.05) in the CRs between retrieved and non-retrieved animals or a significant difference in the CRs of the retrieved group between the last CS-only trial and the retention test. % CR: Percentage of animals that show a proboscis extension response during CS presentation, black circles and bars = retrieved group; grey circles and bars = non-retrieved group; The number of animals tested in the different groups is indicated in parentheses
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