The Journal of Neuroscience, July 13, 2005, ():
Fibroblast Growth Factor 8 Regulates Neocortical Guidance of Area-Specific Thalamic Innervation
J. Neurosci. Shimogori and Grove
25: 6550
Supplemental data
Files in this Data Supplement:
- supplemental material
-
Supplementary Figure 1.
Fate mapping the electroporation site confirms a location confined to dorsal telencephalon. (A) Medial view of an E13.5 R26R hemisphere electroporated with Cre two days earlier. Anterior is to the left. Arrowheads indicate the site of electroporation (blue cells), in the cortical primordium. (B, C) Serial coronal sections through a P6 R26R brain, electroporated with Cre at E11.5. CO staining shows the position of the VB (B). The outline of VB can faintly be seen in (C). Blue cells indicating the electroporation site appear in the dorsomedial cortex (white arrowhead); none are seen in thalamus.
- supplemental material
-
Supplementary Figure 2.
FGF8/17 manipulations shift regional expression of p75. (A – C) Sagittal sections of P1 brains, anterior to left. An arrow indicates the anterior boundary of p75 expression. The normally posterior regional expression of p75 (A), is pulled towards the anterior pole of the cortex by Fgfr3c electroporation at E11.5 (B), and pushed further posterior by electroporation of Fgf8 (C). In (C), a faint line of p75 expression in the subplate (between arrowhead and arrow) extends anterior to expression in the cortical plate.
.gif?ad=17923&adview=true)
