The Journal of Neuroscience, August 3, 2005, ():
The Human Hippocampus: Cognitive Maps or Relational Memory?
J. Neurosci. Kumaran and Maguire
25: 7254
Supplemental data
Files in this Data Supplement:
- supplemental material
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Fig. 1. Example stimulus and results of relational task comparisons.
(A) Schematic representation (never seen by subjects) of one subject’s network of friends. Lines between names indicate two people know each other (see Methods). The spatial arrangement of names represents their relative locations in London.
(B) Cues for relational tasks and an example stimulus array. (C) Brain areas significantly more active when subjects mentally navigated within London (see Results). PHG=parahippocampal gyrus. (D) Brain areas significantly more active when subjects navigated their social network (see Results). MPFC=medial prefrontal cortex; STS=superior temporal sulcus; IFG=inferior frontal gyrus. ‘Glass brain’ figures (displayed above). Activations shown on the averaged structural MRI scan of the 18 participants (displayed below). R=right side of brain. Colours correspond to z-scores (orange/yellow/white in increasing order). Threshold set at p<0.001 uncorrected.
- supplemental material
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Fig. 2. Interaction effect of domain and task.
(A) Sagittal section from the structural MRI scan of one subject chosen at random. The yellow box outlines the region displayed in panel C. The red line indicates the location of the coronal section in the next panel. Threshold set at p<0.001 uncorrected. (B) Coronal section at the level of the peak in right posterior hippocampus. Smaller left hippocampal activation is also evident. (C) Sagittal view showing the extent of activation in the posterior and body of the right hippocampus. (D) Condition-specific parameter estimates (betas) in arbitrary units averaged across subjects, relative to the baseline task at a representative voxel in the centre of cluster in righthippocampus. Bars represent the standard error. Soc R=social relational, Spa R=spatial relational, Soc NR=social non-relational, Spa NR=spatial non-relational.
