supplemental material
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Supplementary Figure S1. Effects of PI3K and Akt on spine density and morphology.
A) Representative micrographs of spines of hippocampal neurons transfected at DIV10 for one week with control vector, constitutively active PI3K (p110*) or Akt (Myr-Akt). Neuron morphology was visualized by cotransfected GFP. B, C and D) Spine density, length and width in neurons transfected as in A. ***, p<0.001; *, p<0.05.