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The Journal of Neuroscience, February 2, 2005, ():

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G-Protein-Coupled Receptor Modulation of Striatal CaV1.3 L-Type Ca2+ Channels Is Dependent on a Shank-Binding Domain
J. Neurosci. Olson et al. 25: 1050

Supplemental data

Files in this Data Supplement:

  • supplemental material - Supplemental figure:  The voltage dependence of current blocked by M1 receptor activation is similar to that of Cav1.3 channels.  A. Activation curves fit with first-order Boltzman functions show the activation of current blocked by muscarine compared to pharmacologically defined Cav1.3 current.  B. Statistical summary of half-activation voltage shows current blocked by muscarine is activated at a low-threshold (median Vh=-20 mV, n=6); resembling Cav1.3 activation (median -22 mV, n=6, p>0.2, Kruskal-Wallis).



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