The Journal of Neuroscience, February 9, 2005, ():
Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival
J. Neurosci. Jaillard et al.
25: 1459
Supplemental data
Files in this Data Supplement:
- Adobe PDF - Supplementary_Table_1.pdf
- supplementary material
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Supplementary Figure S1: Comparative sagittal sections of 21 day postnatal brain from Edg8/S1P5+/+ (A-B) and Edg8/S1P5-/- ( (C-D), showing no clear difference in myelin phenotype usint anti-PLP mAb. A, C illustrate myelinated tracts running through the striatum and B, D isolated myelinated fibers. Arrows point to interruption of labeling suggestive of nodes of Ranvier. Scale bars: 200 mm in A, C; 15mm in B, D.
- supplemental material
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Supplementary Figure S2: Characterization of anti-Edg8 polyclonal antibody. Western blotting of brain extracts with anti Edg8/S1P5 antibody, showing a 37 kDa band in extracts from wild type (+/+) mouse brain and no staining on extracts from Edg8/S1P5-/- brain (-/-)
