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The Journal of Neuroscience, January 4, 2006, ():

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Tumor Necrosis Factor {alpha} But Not Interleukin 1{beta} Mediates Neuroprotection in Response to Acute Nitric Oxide Excitotoxicity
J. Neurosci. Turrin and Rivest 26: 143

Supplemental data

Files in this Data Supplement:

  • supplemental material - Supplementary Movies These 3D reconstructions of FluoroJade B(FJB)-positive regions in the brains of wildtype (wildtype.mov), IL-1β knockout (il-1ko.mov), TNF-α knockout (tnfko.mov) and IL-1β / TNF-α double (Dlb) knockout (doubleko.mov) mice treated with SNP were performed using a C-80 Nikon microscope and super high pressure mercury lamp (Nikon, Montréal, QC) fitted with a Retiga EXi Fast digital camera (QImaging, Burnaby, BC) feeding to a Precision 660 workstation (Dell Computers, North York, ON). The FJB positive regions were traced on a Wacom pen tablet (Wacom, Vancouver, WA) using Neurolucida stereological software package (v.6.02.1, Microbrightfield, Williston, VT) and 3D reconstruction and volume determination were compiled using the Neuroexplorer software (v. 4.01.1, Microbrightfield, Williston, VT) and filmed using HyperCam 2 (Hypertronics Technology, Murrysville, PA). Using the slider at the bottom of the movies to rotate the images, please note the larger volumes of the FJB-positive regions in the TNF and Dbl KO animals compared with that of wildtype and IL-1 KO mice.
  • supplemental material - Supplemental movie
  • supplemental material - Supplemental movie
  • supplemental material - Supplemental movie




This Article
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